Crinecerfont clinical trials
Also written NBI-74788 and Crenessity.
How each study uses crinecerfont is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- 13 Dec 2024 · CRENESSITY · NDA 218808 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
7 studies that test it; most in 2010 (1)
| Year | Studies |
|---|---|
| 2010 | 1 |
| 2018 | 1 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 7 · Other 0
Neurocrine Biosciences (4) · Neurocrine Switzerland GmbH (2) · Sanofi (1)
Studies
Open first, then newest update. How each study uses crinecerfont is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 7
- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years OldRecruitingPhase 2Neurocrine Switzerland GmbHNCT07536269Written as Crinecerfont
- Pharmacokinetics, Safety and Tolerability of Crinecerfont in Participants With Congenital Adrenal Hyperplasia Who Are Less Than 2 Years OldActive, not recruitingPhase 2Neurocrine Switzerland GmbHNCT07187375Written as Crinecerfont
- Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal HyperplasiaActive, not recruitingPhase 3Neurocrine BiosciencesNCT04490915Written as Crinecerfont
- Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Participants With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study)Active, not recruitingPhase 3Neurocrine BiosciencesNCT04806451Written as Crinecerfont
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 (Crinecerfont) in Pediatric Participants With Congenital Adrenal HyperplasiaCompletedPhase 2Neurocrine BiosciencesNCT04045145Written as Crinecerfont
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 in Adults With Congenital Adrenal HyperplasiaCompletedPhase 2Neurocrine BiosciencesNCT03525886Written as NBI-74788
- A Trial Evaluating the Efficacy and Tolerability of SSR125543 in Outpatients With Major Depressive DisorderCompletedPhase 2SanofiNCT01034995Written as SSR125543
Codes
What other systems call crinecerfont · ClinicalTrials.gg INT001928
- MeSH (NLM) C000723083crinecerfontConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) MFT24BX55ICRINECERFONTConfirmed FDA, NLM, Wikidata
- Wikidata Q27088874crinecerfontConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C174708CrinecerfontOne source FDA
- DrugBank DB18518One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000723083 | crinecerfont | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | MFT24BX55I | CRINECERFONT | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q27088874 | crinecerfont | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C174708 | Crinecerfont | One source FDA |
| DrugBank | DB18518 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.