Chelating Agents: all 161 studies that test it
Page 1 of 2. Open to participants first (10), then studies with results posted, then the rest; newest registration first within each.
- Benfotiamine Versus Vitamin B1-6-12 for Diabetic Peripheral NeuropathyRecruitingNCT07708233Phase 4
- Intravenous Chelators in Lead-Burdened Type 2 Diabetic NephropathyNot yet recruitingNCT07706946Not applicable
- Trial of Oral Community SVMP INhibitors for SnakebiteNot yet recruitingNCT07500233Phase 2
- Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized StudyRecruitingNCT06811233Phase 2
- A Crossover Clinical Study to Evaluate the Effect of Chitosan Mouthwash on Recurrence of Black Stains in Pediatric PatientsRecruitingNCT06714695Not applicable
- Calcium-Phosphorus Regulation Therapy on Heart Valve DiseaseRecruitingNCT06660524Phase 4
- A Study of Tetrathiomolybdate (TM) Plus CapecitabineRecruitingNCT06134375Phase 1/2
- Safety and Superiority of Penicillamine in Radiosensitization of Recurrent Head and Neck CancerRecruitingNCT06103617Phase 2
- NBMI Treatment in Patients With Mercury ToxicityRecruitingNCT04183595Phase 2/3
- Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing ChemotherapyRecruitingNCT03630991Phase 1
- Pharmacokinetic Study of Oral ALXN1840 in Japanese and Non-Japanese Adult Healthy ParticipantsCompletedNCT05641311Phase 1Results posted
- A Study of ALXN1840 (Coated and Non-coated) Administered With And Without Omeprazole In Healthy AdultsCompletedNCT05319912Phase 1Results posted
- A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy AdultsCompletedNCT05319899Phase 1Results posted
- Study of Oral ALXN1840 at 2 Dose Strengths in Healthy AdultsCompletedNCT05303324Phase 1Results posted
- Study of ALXN1840 Versus Standard of Care in Pediatric Participants With Wilson DiseaseTerminatedNCT05047523Phase 3Results posted
- Bioavailability Study of 2 Oral Formulations of ALXN1840CompletedNCT04610580Phase 1Results posted
- Copper Balance in Healthy Participants Administered ALXN1840CompletedNCT04594252Phase 1Results posted
- Comparison of Potassium Binders in the ERTerminatedNCT04585542Phase 4Results posted
- Copper and Molybdenum Balance in Participants With Wilson Disease Treated With ALXN1840CompletedNCT04573309Phase 2Results posted
- A Study of the Cardiac Effects of ALXN1840 in Healthy AdultsCompletedNCT04560816Phase 1Results posted
- Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy ParticipantsCompletedNCT04526210Phase 1Results posted
- Phase 1 Study of ALXN1840 on the Metabolism of a CYP2C9 Substrate in Healthy Participants.CompletedNCT04526197Phase 1Results posted
- Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840CompletedNCT04422431Phase 2Results posted
- Study of Chitosan for Pharmacologic Manipulation of AGE Levels in Prostate Cancer PatientsTerminatedNCT03712371Phase 1/2Results posted
- Trial of Trientine Plus Pegylated Liposomal Doxorubicin and Carboplatin in Epithelial Ovarian CancerCompletedNCT03480750Phase 1/2Results posted
- Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Participants With Wilson DiseaseTerminatedNCT03403205Phase 3Results posted
- Evaluation of Renvela in Patients With Chronic Kidney Disease Not On Dialysis And Hyperphosphatemia In ChinaCompletedNCT03001011Phase 3Results posted
- Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition DiseaseTerminatedNCT02947022Phase 1/2Results posted
- Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot UlcersCompletedNCT02789033Phase 3Results posted
- Evaluation of Gadoterate in Patients With Renal DysfunctionTerminatedNCT02382380Phase 4Results posted
- Benfotiamine in Alzheimer's Disease: A Pilot StudyCompletedNCT02292238Phase 2Results posted
- Efficacy and Safety Study of WTX101 (ALXN1840) in Adult Wilson Disease PatientsCompletedNCT02273596Phase 2Results posted
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)CompletedNCT02127125Phase 2Results posted
- Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1)CompletedNCT02124759Phase 2Results posted
- Safety and Efficacy of Sodium Polystyrene Sulfonate in HyperkalemiaTerminatedNCT01866709Phase 4Results posted
- An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney DiseaseCompletedNCT01574326Phase 2Results posted
- Sevelamer for Reducing Endotoxemia and Immune ActivationCompletedNCT01543958Phase 2Results posted
- Single Daily Dosage of Trientine for Maintenance Treatment for Wilson DiseaseCompletedNCT01472874Not applicableResults posted
- The Effect(s) of Sevelamer Carbonate (Renvela) on Atherosclerotic Plaque Inflammation Judged by FDG-PET ScanTerminatedNCT01238588Not applicableResults posted
- Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney DiseaseCompletedNCT01191762Phase 3Results posted
- FGF-23 (Fibroblast Growth Factor 23) Regulation in Chronic Kidney DiseaseCompletedNCT00999037Not applicableResults posted
- The Pharmacokinetics of Rocaltrol When Administered Alone or in Combination With Fosrenol or Renvela in Healthy VolunteersCompletedNCT00925704Phase 1Results posted
- Study of Phosphate Levels in Patients With Chronic Kidney DiseaseCompletedNCT00824460Phase 2Results posted
- A Double Blind Randomized Placebo Trial of Maintenance of Normal Serum Phosphorus in CKDCompletedNCT00785629Not applicableResults posted
- High Dose Vitamin B1 to Reduce Abusive Alcohol UseCompletedNCT00680121Phase 4Results posted
- Phase II Study of Tetrathiomolybdate (TM) in Patients With Breast CancerTerminatedNCT00195091Phase 2Results posted
- Chemoradiation and Tetrathiomolybdate (TM) in Patients With Esophageal CarcinomaCompletedNCT00176800Phase 2Results posted
- A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Japanese Healthy Pregnant WomenActive, not recruitingNCT07596199Phase 3
- Effectiveness of Hydroxyapatite Reinforced Chitosan Hydrogel in Modulation of OsseointegrationCompletedNCT06758440Not applicable
- Clinical Assessment of Chitosan Nanoparticles on Periodontal Problems Post Steroidal Inhalation in Asthmatic Patients: Phase I TrialCompletedNCT06525363Phase 1
- Comparison of Chitosan, Ankaferd and Tranexamic Acid in Dental Extraction in Liver Pre-Transplant ChildrenCompletedNCT06457360Early Phase 1
- A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)Active, not recruitingNCT06223360Phase 2
- The Anti-fungal Effect of Miconazol Versus Miconazol-Loaded Chitosan NanoparticlesCompletedNCT06072716Phase 1
- SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis PatientsCompletedNCT06029179Not applicable
- Amino Acid Kinetics of GMP-AA in Healthy Human VolunteersCompletedNCT05971563Not applicable
- Use of Chitosan Powder in Loop Electrosurgical Excision ProcedureCompletedNCT05661708Phase 4
- DTPA (Diethylenetriaminepenta-acetate) Chelation for Symptoms After Gadolinium-assisted MRI ExposureWithdrawnNCT05359835Early Phase 1
- The Efficacy and Mechanism of Trientine in Patients With Hypertrophic CardiomyopathyCompletedNCT04706429Phase 2
- MicroFIBERgut: Effects of Lifestyle Changes and Chitosan on Gut Microbiota and Weight ManagementCompletedNCT04551365Not applicable
- Study of NBMI Treatment in Patients With Atypical Parkinsons (PSP or MSA)CompletedNCT04184063Phase 2
- Phase 2a Pilot Study of NBMI Treatment in Patients With Beta Thalassemia Major, Requiring Iron ChelationCompletedNCT04092205Phase 2
- The Individual Therapy for Patients With Wilson's DiseaseStatus unknownNCT03957720Early Phase 1
- GLP-1-mediated Gluco-metabolic Effects of Bile Acid SequestrationCompletedNCT03739268Not applicable
- Effect of Using Nanochitosan Versus Calcium Hydroxide as Disinfectant on Pain and Apical Bone HealingStatus unknownNCT03724266Not applicable
- Assessment of Pain and Antibacterial Activity of Chitosan Versus Sodium Hypochlorite as Irrigant in Infected CanalStatus unknownNCT03719261Phase 2/3
- The Effect of Sevelamer Carbonate on Serum Trimethylamine-n-Oxide (TMAO) Level in Patients With Chronic Kidney Disease (CKD) Stage 3b-4Status unknownNCT03596749Phase 3
- Chitosan,Chitosan Nanoparticles,and Chlorhexidine Gluconate, as Intra Canal Medicaments in Primary TeethStatus unknownNCT03588351Not applicable
- Real-time Amino Acid ProfilingCompletedNCT03547362Not applicable
- Different Effects of Non-calcium Phosphate Binders on Serum CalciumCompletedNCT03451019Phase 4
- Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute DiseaseCompletedNCT03319550Not applicable
- DS2330b Alone and With Sevelamer in Patients on Chronic HemodialysisCompletedNCT03305471Phase 1
- Hyperphosphatemia in Children With Chronic Kidney DiseaseStatus unknownNCT03202407Phase 3
- NBMI - Clinical Study on COPDCompletedNCT03123692Phase 2
- Delivery of Inhibitors of Lysyl Oxidase (LysoLox) on Serial Angioplasty and Time to RestenosisStatus unknownNCT03106948Phase 2
- Efficacy of Dotarem® (Gd-DOTA) Versus Gadovist® (Gd-DO3A-butrol) for Late Gadolinium Enhancement Cardiac Magnetic ResonanceCompletedNCT03057561Not applicable
- Phosphate in Blood Pressure RegulationCompletedNCT02822131Not applicable
- Benfotiamine Effect on Advanced Glycation End Products(AGEs) and Soluble Receptor for AGEs(sRAGE) in Diabetes Mellitus.CompletedNCT02772926Not applicable
- Comparison of Oral Morphine Versus Nasal Ketamine Spray With Chitosan in Cancer Pain OutpatientsTerminatedNCT02591017Phase 3
- Pilot Proof of Concept Study of NBMI Treatment of Mercury IntoxicationCompletedNCT02486289Phase 2
- Effect of Bile Acid Secretion and Sequestration on GLP-1 SecretionCompletedNCT02445508Not applicable
- Study to Assess Long-Term Outcomes of Trientine in Wilson Disease Patients Withdrawn From Therapy With d-PenicillamineStatus unknownNCT02426905Phase 4
- An Open Label, Dose Titration Study of Sevelamer Carbonate Tablets & Powder in Hyperphosphatemic CKD PatientsCompletedNCT02332811Phase 3
- Validation of New Markers of Glomerular Filtration Rate: Dota Gadolinium and Calcium EDTA (MultiGFR)TerminatedNCT02286258Phase 1/2
- Effect of Sevelamer on P-cresol Levels in CKDStatus unknownNCT02199444Phase 3
- A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic MelanomaWithdrawnNCT02068079Phase 1
- Efficacy of Sodium Polystyrene Sulfonate in the Treatment of Hyperkaliemia in Pre-dialysis PatientsCompletedNCT02065076Phase 4
- Effect of Bile Acid Sequestration on Postprandial GLP-1 Secretion, Glucose Homeostasis and Gut MicrobiotaCompletedNCT02061124Not applicable
- Sevelamer in Proteinuric CKDCompletedNCT01968759Phase 2
- A Phase 1 Study to Assess the Effects in the Body of a Single Dose of Trientine Dihydrochloride in Wilson's Disease PatientsCompletedNCT01874028Phase 1
- Effects of Benfotiamine on Intraepidermal Nerve Fiber Density (IENFD)Status unknownNCT01868191Phase 3
- Phase I Study of Tetrathiomolybdate in Combination With Carboplatin/Pemetrexed in Metastatic Non-small Cell Lung CancerCompletedNCT01837329Phase 1
- Long Term Evaluation of Sevelamer HCl vs. Calcium-based Phosphate Binder in the Treatment of Hyperphosphatemia in Hemodialysis PatientsCompletedNCT01755078Phase 4
- Dose-Titration Study of Sevelamer Carbonate in Chronic Kidney Disease (CKD) Patients on HemodialysisCompletedNCT01736150Phase 3
- The Effect of Different Macronutrients on Ileal Brake ActivationCompletedNCT01509469Not applicable
- The Effects of Sevelamer Carbonate on Diabetic NephropathyCompletedNCT01493050Phase 2
- Dairy Lipids, Proteins, and the Metabolic Syndrome - "DairyHealth"CompletedNCT01472666Not applicable
- Disturbances in BCAA Metabolism and the Effects of Feeding and Exercise in COPDCompletedNCT01418469Not applicable
- Effects of a Non-Calcium Based Phosphate Binder on FGF23 Levels in Chronic Kidney DiseaseCompletedNCT01308242Early Phase 1
- Trientine Hydrochloride for the Prevention of Macular Edema After Cataract Surgery in Patients With Type 2 Diabetes MellitusWithdrawnNCT01295073Phase 2
- Effect of Phosphate Binders on Markers of Vascular Health in Chronic Kidney Disease Stages 3 and 4TerminatedNCT01277497Phase 4