Drug
CDX-301 clinical trials
Also written CDX-301.
A product of flt3 ligand protein; its studies count on that page too.
- studies test it
- 10
- open now
- 2
- in phase 3
- 0
- first study started
- 2011
Keep track of what changes. Save the CDX-301 studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
10 studies that test it; most in 2014 (3)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2014 | 3 |
| 2016 | 1 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 6
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 3 · Other 7
Celldex Therapeutics (3) · Ashutosh Kumar Tewari (1) · Montefiore Medical Center (1) · Parker Institute for Cancer Immunotherapy (1) · Joshua Brody (1) · University of Texas Southwestern Medical Center (1) · Weill Medical College of Cornell University (1) · Washington University School of Medicine (1)
Often tested with
Tested in the same studies.
Poly ICLC (2) · Bempegaldesleukin (1) · DNA Plasmid-encoding Interleukin-12 INO-9012/PSA/PSMA DNA Plasmids INO-5150 Formulation INO-5151 (1) · CDX-1140 (1) · Glembatumumab vedotin (1) · Varlilumab (1) · Plerixafor (1)
Studies
Open first, then newest update. How each study uses CDX-301 is read from its arms, and is right about nine times in ten.
Testing it · 10
- CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast CancerRecruitingPhase 1University of Texas Southwestern Medical CenterNCT05029999Written as CDX-301
- Converting HR+ Breast Cancer Into an Individualized VaccineRecruitingPhase 2Weill Medical College of Cornell UniversityNCT03804944Written as CDX-301
- FLT3 Ligand Immunotherapy and Stereotactic Radiotherapy for Advanced Non-small Cell Lung CancerCompletedPhase 2Montefiore Medical CenterNCT02839265Written as FLT3 Ligand Therapy (CDX-301)
- The Safety and Tolerability of PGV001-based Personalized Multi-peptide Vaccines in the Adjuvant Setting.Active, not recruitingPhase 1Ashutosh Kumar TewariNCT05010200Written as CDX-301
- Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer PatientsTerminatedPhase 2Washington University School of MedicineNCT04536077Written as CDX-301
- Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel CombinationsCompletedPhase 1Parker Institute for Cancer ImmunotherapyNCT03835533Written as CDX-301 (Cohort B and C)
- In Situ Vaccine for Low-Grade Lymphoma: Combination of Intratumoral Flt3L and Poly-ICLC With Low-Dose RadiotherapyCompletedPhase 1/2Joshua BrodyNCT01976585Written as rhuFlt3L/CDX-301
- A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced MelanomaTerminatedPhase 2Celldex TherapeuticsNCT02302339Written as glembatumumab vedotin and CDX-301
- A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy VolunteersCompletedPhase 1Celldex TherapeuticsNCT01465139Written as CDX-301
- A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant PairsTerminatedPhase 2Celldex TherapeuticsNCT02200380Written as CDX-301
Given in every arm · 2 — CDX-301 is usual care beside what is tested
- NeoVax + CDX-301 and Nivolumab or Pembrolizumab in MelanomaActive, not recruitingPhase 1Dana-Farber Cancer InstituteNCT04930783Written as CDX-301
- A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesCompletedPhase 1Celldex TherapeuticsNCT03329950Written as CDX-301