Bupropion: all 215 studies that test it

Page 1 of 3. Open to participants first (13), then studies with results posted, then the rest; newest registration first within each.

• The BAARD Study : Evaluating a Computerized Approach to Treatment Selection in Older Adults With Treatment Resistant Depression.Not yet recruitingNCT07810738Phase 2
• Lifestyle Changes, Mushroom Supplementation, and Bupropion to Reduce Adiposity and Cardiometabolic RiskNot yet recruitingNCT07806279Phase 3
• Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)RecruitingNCT07766655Phase 3
• A Phase 1, First-in-human Study of VX-433RecruitingNCT07584434Phase 1
• Individualized Pharmacological Approach to Obesity in Patients With Bipolar DisorderRecruitingNCT07213466Phase 4
• Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)Enrolling by invitationNCT06845345Phase 4
• Improving Efficacity of Sleeve Gastrectomy With Naltrexone/Bupropion Extended-release TabletRecruitingNCT06620562Phase 4
• Bupropion for Fatigue in End-stage Kidney Disease Patients on HemodialysisNot yet recruitingNCT06609343Phase 1/2
• Effectiveness of Combined Tobacco Treatment in Hospitalized SubjectsRecruitingNCT06254001Phase 4
• The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.RecruitingNCT05973786Phase 3
• Improving Smoking Abstinence Outcomes in the African American Community Through Extended TreatmentRecruitingNCT05732272Phase 3
• Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment FailureRecruitingNCT05603104Phase 3
• Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive DisorderNot yet recruitingNCT02129751Phase 4
• A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the BloodCompletedNCT06367153Phase 1Results posted
• A Study in Healthy Men and Women to Test Whether BI 1358894 Influences the Amount of Bupropion in the BloodCompletedNCT04899674Phase 1Results posted
• EMI-EHP Weight Management and Type 2 Diabetes Pragmatic TrialTerminatedNCT04531176Phase 4Results posted
• eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes RiskCompletedNCT04437485Phase 2Results posted
• Zonisamide/Bupropion Effects on Switching to Electronic CigarettesCompletedNCT04388319Phase 3Results posted
• Bupropion Versus Escitalopram on Reward Circuitry and Motivational DeficitsCompletedNCT04352101Phase 4Results posted
• Varenicline and Bupropion for Alcohol Use DisorderCompletedNCT04167306Phase 2Results posted
• Mobile Evidence-Based Smoking Cessation for Veterans Living With HIV (MESH)CompletedNCT04135937Phase 4Results posted
• Promoting Enhanced Pharmacotherapy Choice Through Immunomarkers Evaluation in DepressionTerminatedNCT03993457Phase 4Results posted
• Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-RespondersCompletedNCT03946111Phase 2/3Results posted
• Investigation of Genetic Predictors of the Response to Selective Serotonin Re-uptake Inhibitors (SSRI) TreatmentCompletedNCT03927950Phase 4Results posted
• Individualizing Pharmacotherapy for African American SmokersCompletedNCT03897439Phase 3Results posted
• Smoking Cessation Interventions for People Living With HIV in Nairobi, KenyaCompletedNCT03342027Phase 3Results posted
• Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic CancerCompletedNCT03180294Phase 2Results posted
• Buproprion for Binge DrinkingCompletedNCT03169244Phase 2Results posted
• Optimizing Outcomes of Treatment-Resistant Depression in Older AdultsCompletedNCT02960763Phase 4Results posted
• Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)CompletedNCT02873754Not applicableResults posted
• Mobile Contingency Management for Marijuana and Tobacco CessationCompletedNCT02869451Not applicableResults posted
• An Open Label Trial of Bupropion and Naltrexone for Binge DrinkingCompletedNCT02842073Phase 2Results posted
• Naltrexone and Bupropion Combination on Obese,Smoking Patients With SchizophreniaCompletedNCT02736474Phase 4Results posted
• Naltrexone/Bupropion Cardiovascular Outcomes StudyTerminatedNCT02638129Phase 4Results posted
• Drug-Drug Interaction Study: ASP2151 and BupropionCompletedNCT02369172Phase 1Results posted
• Bupropion for Depression in ESRD Patients on HemodialysisTerminatedNCT02238977Phase 4Results posted
• Clinical Study of Generic and Brand Bupropion in DepressionCompletedNCT02209597Phase 4Results posted
• Study to Evaluate the Efficacy, Safety and Tolerability of Bupropion Hydrochloride Extended-release Tablet, and Escitalopram Oxalate Capsule in Subjects With Major Depressive DisorderCompletedNCT02191397Phase 3Results posted
• Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant WomenCompletedNCT02188459Phase 2Results posted
• Treating Disrupted Sleep in Individuals With Inflammatory Bowel DiseaseCompletedNCT02162862Phase 4Results posted
• Bupropion-Enhanced Contingency Management (CM) for Cocaine DependenceCompletedNCT02111798Phase 2/3Results posted
• Pharmacokinetic Study of Bupropion Hydrochloride Products With Different Release PatternsCompletedNCT02078180Phase 4Results posted
• Accelerated Development of Additive Pharmacotherapy Treatment for Methamphetamine Use DisorderCompletedNCT01982643Phase 1/2Results posted
• Combination Bupropion / Varenicline for Smoking Cessation in Male SmokersCompletedNCT01806779Phase 2Results posted
• An Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich AtaxiaCompletedNCT01716221Phase 4Results posted
• Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.CompletedNCT01574703Phase 4Results posted
• Tailored Smoking Cessation Treatment for LIVE FOR LIFE® ParticipantsTerminatedNCT01560507Phase 2/3Results posted
• Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric DisordersCompletedNCT01456936Phase 4Results posted
• Mechanistic Evaluations of Pre-Cessation Therapies for Smoking CessationCompletedNCT01406223Phase 3Results posted
• Bupropion for Smoking Cessation During PregnancyCompletedNCT01390246Phase 4Results posted
• Extended Treatment for Smoking CessationCompletedNCT01330043Phase 4Results posted
• Concurrent Bupropion / Varenicline for Smoking CessationCompletedNCT01303861Phase 3Results posted
• Double-blind, Placebo-Controlled Pilot Study of Bupropion to Promote Smoking Cessation During PregnancyCompletedNCT01286402Phase 2Results posted
• Efficacy Of Bupropion For Attention Deficit Hyperactivity Disorder (ADHD) In AdultsCompletedNCT01270555Not applicableResults posted
• Symptom Burden in Head and Neck CancerTerminatedNCT01219673Phase 1/2Results posted
• Nicotine Replacement Therapy (NRT) and Bupropion Mechanisms of Effectiveness in SmokersCompletedNCT01048944Phase 4Results posted
• Distribution of Bupropion and Varenicline to Increase Smoking Cessation AttemptsCompletedNCT01023659Phase 4Results posted
• STOP Study: Effectiveness of Zyban in a Clinical PopulationCompletedNCT01015170Phase 4Results posted
• Pilot Trial of Bupropion Versus Placebo for Methamphetamine Abuse in AdolescentsCompletedNCT00994448Phase 2Results posted
• Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar Disorder.TerminatedNCT00958633Phase 3Results posted
• Combining Varenicline and Bupropion for Smoking CessationCompletedNCT00943618Phase 3Results posted
• Bupropion for ADHD in Adolescents With Substance Use DisorderCompletedNCT00936299Phase 4Results posted
• Varenicline and Bupropion for Smoking CessationCompletedNCT00935818Phase 2/3Results posted
• Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and GenotypeCompletedNCT00894166Phase 3Results posted
• Study of Medical Treatment for Methamphetamine AddictionCompletedNCT00833443Phase 2Results posted
• Human Laboratory Study of Varenicline and Bupropion for Nicotine DependenceCompletedNCT00749658Phase 2/3Results posted
• Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA TrialCompletedNCT00689611Phase 3Results posted
• Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine DependenceCompletedNCT00687713Phase 2Results posted
• Health Education Counseling With or Without Bupropion in Helping African Americans Stop SmokingCompletedNCT00666978Phase 4Results posted
• Bupropion and Restless Legs SyndromeCompletedNCT00621517Phase 2/3Results posted
• Effect of Antidepressants on Sex Hormone Levels and Sexual FunctioningCompletedNCT00611975Phase 4Results posted
• Combining Medications to Enhance Depression OutcomesCompletedNCT00590863Phase 4Results posted
• Chantix & Bupropion for Smoking CessationCompletedNCT00587769Phase 3Results posted
• The Effect of Varenicline (Chantix) and Bupropion (Zyban) on Smoking Lapse BehaviorCompletedNCT00580853Phase 2Results posted
• Bupropion in the Treatment of Methamphetamine DependenceCompletedNCT00572234Not applicableResults posted
• Bupropion in Helping Adults Stop SmokingCompletedNCT00534001Phase 2Results posted
• Early Detection and Intervention for the Prevention of PsychosisCompletedNCT00531518Not applicableResults posted
• Does Dual Therapy Hasten Antidepressant Response?CompletedNCT00519428Phase 4Results posted
• Pharmacogenetics, Emotional Reactivity and SmokingCompletedNCT00507728Phase 2/3Results posted
• Fluoxetine and Bupropion to Treat Patients With Depression and AlcoholismTerminatedNCT00449007Phase 4Results posted
• Paroxetine/Bupropion in Suicide Attempters/Ideators With Major DepressionTerminatedNCT00429169Phase 4Results posted
• Craving, Binge Eating and ObesityCompletedNCT00414167Phase 2/3Results posted
• Dichotic Listening as a Predictor of Medication Response in DepressionCompletedNCT00404755Phase 4Results posted
• Smoking Cessation Medications: Efficacy, Mechanisms and AlgorithmsCompletedNCT00332644Phase 4Results posted
• Combined Pharmaco/Behavior Therapy in Adolescent SmokersCompletedNCT00330187Phase 2Results posted
• Acceptability of Pharmacologic Treatment for Methamphetamine Dependence Among MSMCompletedNCT00318409Phase 2Results posted
• Effectiveness of Bupropion for Smokers Recovering From Alcohol DependenceCompletedNCT00304707Phase 3Results posted
• Smoking Cessation Intervention: Effectiveness in Primary CareCompletedNCT00296647Phase 4Results posted
• Bupropion For Reducing High-Risk Behaviors in Depressed Men Who Have Sex With Men (MSM)CompletedNCT00285584Phase 1Results posted
• Wellbutrin XL for Dysthymic DisorderCompletedNCT00225251Phase 4Results posted
• Contingent Incentives Plus Bupropion for Smoking in People With SchizophreniaCompletedNCT00136760Phase 2Results posted
• Study Of 323U66 SR In Major Depressive DisorderCompletedNCT00135512Phase 2Results posted
• The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated DepressionCompletedNCT00125957Phase 3Results posted
• Comparing Smoking Treatment Programs for Lighter Smokers - 1CompletedNCT00086411Phase 2Results posted
• Maintaining Nonsmoking: Older Smokers - 1CompletedNCT00086385Phase 3Results posted
• Bupropion and Weight Control for Smoking Cessation - 1CompletedNCT00006170Phase 4Results posted
• Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult ParticipantsCompletedNCT07235748Phase 1
• Smoking Cessation Trial in Recurrent Acute Pancreatitis and Chronic PancreatitisWithdrawnNCT07171112Phase 2
• A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy ParticipantsCompletedNCT06973005Phase 1
• A Study to Test Whether BI 456906 (Survodutide) Influences the Amount of Bupropion, Caffeine and Midazolam in the Blood in People With Overweight or ObesityCompletedNCT06564441Phase 1

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