Bardoxolone methyl: all 34 studies that test it

Page 1 of 1. Open to participants first (0), then studies with results posted, then the rest; newest registration first within each.

• A Trial of Bardoxolone Methyl in Patients With CKD at Risk of Rapid Progression (MERLIN)CompletedNCT04702997Phase 2Results posted
• BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19)CompletedNCT04494646Phase 2Results posted
• A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCONTerminatedNCT03918447Phase 3Results posted
• An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)TerminatedNCT03749447Phase 3Results posted
• A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIXCompletedNCT03366337Phase 2Results posted
• Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGERTerminatedNCT03068130Phase 3Results posted
• A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINALCompletedNCT03019185Phase 2/3Results posted
• Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYSTTerminatedNCT02657356Phase 3Results posted
• Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIATCompletedNCT02036970Phase 2Results posted
• A Clinical Pharmacology Study of Bardoxolone Methyl in Healthy AdultsCompletedNCT04023903Phase 1
• A Study of RTA 402 in Obese AdultsCompletedNCT04018339Phase 1
• A Phase 3 Study of Bardoxolone Methyl in Patients With Diabetic Kidney Disease; AYAME StudyTerminatedNCT03550443Phase 3
• Effect of Itraconazole on the Pharmacokinetics of Bardoxolone Methyl in Healthy AdultsCompletedNCT03264079Phase 1
• The Phase II Study of Bardoxolone Methyl in Patients With Chronic Kidney Disease and Type 2 Diabetes; TSUBAKI StudyCompletedNCT02316821Phase 2
• Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval VolunteersCompletedNCT01689116Phase 1
• A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Effects of Bardoxolone Methyl on Body Composition in Patients With Stage 4 Chronic Kidney Disease and Type 2 Diabetes MellitusWithdrawnNCT01655186Phase 2
• A Double-Blind, Randomized, Placebo-Controlled Safety Study Evaluating the Effects of Residual Renal Function (RFF) in Patients With End-Stage Renal Disease and Type 2 Diabetes Mellitus on Peritoneal DialysisWithdrawnNCT01576887Phase 2
• A Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes MellitusTerminatedNCT01574365Phase 2
• A Glomerular Filtration Rate (GFR) Measuring Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes MellitusTerminatedNCT01572610Phase 2
• Single-Dose, Open-Label Pharmacokinetic Study of Bardoxolone Methyl in Subjects With Mild, Moderate, and Severe Hepatic Impairment and Normal Hepatic FunctionCompletedNCT01563562Phase 1
• Pilot Assessment of the Effects of Bardoxolone Methyl on Renal Perfusion, Systemic Haemodynamics and Cardiac Function in Patients With Chronic Kidney Disease and Type 2 DiabetesWithdrawnNCT01551446Phase 1
• Pharmacokinetic and Pharmacodynamic Study of Bardoxolone Methyl in Patients With Chronic Kidney Disease and Type 2 DiabetesTerminatedNCT01549769Phase 1
• A Phase I Study to Investigate the Absorption, Metabolism and Excretion in Healthy Male SubjectsCompletedNCT01503866Phase 1
• A Pharmacodynamic Study of Measured Glomerular Filtration Rate in Patients With Chronic Kidney Disease and Type 2 DiabetesTerminatedNCT01500798Phase 1
• A Single-Dose, Open-Label, Randomized, Food Effect and Blinded, Randomized, Dose Proportionality Study in Healthy Volunteers With Bardoxolone MethylCompletedNCT01461161Phase 1
• Bardoxolone Methyl Evaluation in Patients With Chronic Kidney Disease and Type 2 DiabetesTerminatedNCT01351675Phase 3
• Phase II Pharmacodynamic Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney DiseaseCompletedNCT01053936Phase 2
• Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney DiseaseCompletedNCT00811889Phase 2
• Phase IIa Trial to Determine the Effects of Bardoxolone Methyl on Renal Function in Patients With Diabetic NephropathyCompletedNCT00664027Phase 2
• Study to Assess the Safety, Tolerability, and Pharmacodynamics of RTA 402 in Patients With Hepatic DysfunctionTerminatedNCT00550849Phase 1/2
• Study of Two Dose Levels of RTA 402 in Patients With Advanced Malignant MelanomaWithdrawnNCT00535314Phase 2
• RTA 402 in Patients With Advanced Solid Tumors or Lymphoid MalignanciesCompletedNCT00529438Phase 1
• Study With Gemcitabine and RTA 402 for Patients With Unresectable Pancreatic CancerTerminatedNCT00529113Phase 1
• RTA 402 in Advanced Solid Tumors or Lymphoid MalignanciesCompletedNCT00508807Phase 1

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