Antimetabolites: all 8,294 studies that test it

Page 10 of 83. Open to participants first (1,149), then studies with results posted, then the rest; newest registration first within each.

• Neoadjuvant Chemotherapy for Pancreatic Cancer Followed by GS and GnPRecruitingNCT05268692Phase 2/3
• Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver CancerRecruitingNCT05265208Phase 2
• Perioperative FLOT vs Adjuvant XELOX for CA StomachRecruitingNCT05264896Phase 3
• Microtransplantation Combined With Azacytidine to Improve the Efficacy of EAMLRecruitingNCT05262465Not applicable
• R-CDOP Combined With Intrathecal Methotrexate for DLBCL Patients With High-risk of CNS RelapseRecruitingNCT05257018Phase 2
• Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic AdenocarcinomaRecruitingNCT05241249Phase 2
• Envafolimab Combined With Chemotherapy in Metastatic or Recurrent Gastric AdenocarcinomaRecruitingNCT05237349Phase 2
• PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal CancerRecruitingNCT05236972Phase 3
• Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian CancerRecruitingNCT05225363Phase 1
• A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCCRecruitingNCT05221658Phase 2
• Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic CancerRecruitingNCT05218889Phase 1/2
• Efficacy of Supplement Adjuvant Capecitabine in HR+/HER2- Breast Cancer Patients With High RisksRecruitingNCT05212454Phase 3
• Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System LymphomaRecruitingNCT05209620Phase 2
• A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)RecruitingNCT05190471Phase 1
• Study of Neoadjuvant Chemotherapy Versus Definite Concurrent Chemoradiotherapy for Locally Advanced Bulk Cervical CancerRecruitingNCT05189028Phase 3
• First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural MesotheliomaRecruitingNCT05188859Phase 2
• Penpulimab Plus R2-GemOx Regimen in Relapsed or Refractory DLBCLNot yet recruitingNCT05186558Phase 2
• SHR6390 Plus Nab-paclitaxel and Gemcitabine in Advanced/Metastatic Pancreatic CancerNot yet recruitingNCT05185869Phase 2
• Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AMLRecruitingNCT05184842Phase 2Results posted
• A Phase 2 Study of Neoadjuvant Docetaxel, Oxaliplatin, S-1 in Patients With Unresectable Locally Advanced or Distant Metastasis Limited to Lymph Node Gastric CancerRecruitingNCT05184803Phase 2
• Clinical Study on Anti-PD-1 Plus Lenalidomide and Azacitidine in Relapsed/Refractory Peripheral T-cell LymphomaRecruitingNCT05182957Phase 2
• Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin LymphomaRecruitingNCT05180097Phase 2
• Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer (AuspiCiOus)RecruitingNCT05177133Phase 2
• The Neoadjuvant Treatment of Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma.RecruitingNCT05170542Phase 2
• SALIRI Based Regimen as First-line Treatment for Advanced Metastatic Colorectal CancerRecruitingNCT05160896Phase 2
• Induction Chemotherapy and Tazemetostat for Locally Advanced SMARCB1-deficient Sinonasal CarcinomaNot yet recruitingNCT05151588Phase 2
• A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic SyndromeRecruitingNCT05140811Phase 1/2
• A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)RecruitingNCT05139017Phase 2/3
• Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal CancerRecruitingNCT05136326Phase 2
• Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System LymphomaRecruitingNCT05135858Phase 1
• AZA Combined With NAC for PIT After HSCTNot yet recruitingNCT05126004Phase 2
• Recombinant Human Adenovirus Type 5 Plus HAIC of FOLFOX for Intrahepatic CholangiocarcinomaRecruitingNCT05124002Phase 4
• New Clinical End-points in Patients With Primary Sjögren's SyndromeRecruitingNCT05113004Phase 2
• Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other CancersRecruitingNCT05098132Phase 1/2
• A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Capecitabine in Patients with Metastatic Colorectal CancerRecruitingNCT05093907Phase 1/2
• Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological MalignancesRecruitingNCT05092451Phase 1/2
• Trifluridine/Tipiracil Combined With Oxaliplatin and Bevacizumab Versus XELOX Plus Bevacizumab in mCRCRecruitingNCT05077839Phase 2
• Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative NeoplasmsRecruitingNCT05074355Phase 2
• Investigator-initiated Clinical Trial of MIKE-1RecruitingNCT05064618Phase 1/2
• Adjuvant Metronomic Capecitabine Plus Endocrine Therapy for HR+/HER2- Primary Breast CancerRecruitingNCT05063136Phase 3
• ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver MetastasesRecruitingNCT05062317Phase 2
• Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung CancerRecruitingNCT05061550Phase 2
• Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone TumorsRecruitingNCT05057130Phase 2/3
• Efficacy and Biomarker Development for Lung Cancer Treated With Immune Checkpoint InhibitorsRecruitingNCT05055908Phase 3
• Intermediate Dose of IV MTX as CNS Prophylaxis for High Risk DLBCLRecruitingNCT05054426Phase 3
• Peri-operative SLOG for Localized Pancreatic CancerRecruitingNCT05048524Phase 2
• Single-agent Capecitabine as Metronomic Chemotherapy in LAHNSCC (CMHN)RecruitingNCT05044117Phase 3
• Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)RecruitingNCT05041907Phase 2
• Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled TrialRecruitingNCT05040464Phase 3
• Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine TumorsRecruitingNCT05040360Phase 2
• TAS-102 and Anlotinib in ≥3 Lines mGCRecruitingNCT05029102Phase 2
• Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AMLRecruitingNCT05024552Phase 1
• GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor MalignanciesRecruitingNCT05003895Phase 1
• Perioperative Leucovorin, Oxaliplatin, Docetaxel and S-1 (LOTS) For Locally Advanced Gastric or Gastroesophageal Junction CancerRecruitingNCT04999332Phase 2
• Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies and HER2 Negative Breast CancerRecruitingNCT04997993Phase 1
• Phase IB/II of CPX-351 for Relapse Prevention in AMLRecruitingNCT04990102Phase 1/2
• Bisantrene Combination for Resistant AMLRecruitingNCT04989335Phase 2
• Using ctDNA to Determine Therapies for Lung CancerRecruitingNCT04966663Phase 2
• HAIC With FOLFOX Versus Systemic Chemotherapy With GP for Unresectable ICCRecruitingNCT04961970Phase 3
• Outcomes of Patients After Allo-HSCT With Decitabine and NACNot yet recruitingNCT04945096Phase 3
• Combination of Metronomic Capecitabine With Camrelizumab for Treatment of Refractory Solid Tumor Trial (Cohort 3)RecruitingNCT04932187Phase 1
• Stage I HER2 Positive Invasive Breast Cancer De-escalation Study(IRIS-C/D)Not yet recruitingNCT04922008Phase 2
• Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon AdenocarcinomasRecruitingNCT04920032Phase 1
• Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent FailureRecruitingNCT04905810Phase 2
• Induction Versus Adjuvant Gemcitabine/Cisplatin in Locally Advanced Non-metastatic Nasopharyngeal CarcinomaRecruitingNCT04898374Phase 3
• Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic CancerRecruitingNCT04894643Not applicable
• Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With SurgeryRecruitingNCT04891289Phase 2
• BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast CancerRecruitingNCT04891068Phase 2
• An Open-label, Multicentre, Phase II/III RCT of PFLL Versus GP Combined With JS001 as the First-line Therapy for mNPCNot yet recruitingNCT04890522Phase 2/3
• Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ LeukemiaRecruitingNCT04881240Phase 1
• Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin LymphomaRecruitingNCT04871607Phase 2
• Efficacy of Hyperthermic Intraperitoneal ChemotherapyRecruitingNCT04861558Phase 3
• Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingNCT04847063Phase 1
• Penpulimab-based Combination Neoadjuvant/Adjuvant Therapy for Patients With Resectable Locally Advanced Non-small Cell Lung Cancer: a Phase II Clinical Study (ALTER-L043)Not yet recruitingNCT04846634Phase 2
• Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel ObstructionRecruitingNCT04840264Phase 2
• Clinical Study of ssCART-19 Cells in Patients With CD19 Positive Relapsed or Refractory Acute Lymphoblastic LeukemiaRecruitingNCT04825496Phase 1
• A Prospective, Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After Adjuvant Chemotherapy in TNBCRecruitingNCT04803539Phase 2/3
• Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell LymphomaRecruitingNCT04803201Phase 2
• Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion SyndromeRecruitingNCT04802707Phase 2
• Efficacy, Safety and Costs of Methotrexate, Adalimumab, or Their Combination in Non-infectious Non-anterior UveitisRecruitingNCT04798755Phase 3
• Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid NeoplasmsRecruitingNCT04797767Phase 1/2
• Optimal Duration of Oxaliplatin in Adjuvant XELOX for Gastric Cancer Patients (EXODOX)RecruitingNCT04787354Phase 3
• A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained ProtocolRecruitingNCT04773366Phase 3
• Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast CancerRecruitingNCT04768426Phase 2
• Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour ResectionEnrolling by invitationNCT04762459Phase 3
• Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)RecruitingNCT04747912Phase 2
• Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCLRecruitingNCT04747236Phase 2
• Evaluating the Efficacy and Safety of Bevacizumab, Carboplatin, Gemcitabine and Atezolizumab in Breast CancerRecruitingNCT04739670Phase 2
• Rituximab, Lenalidomide Combined With Methotrexate and Temozolomide For Primary Central Nervous System LymphomaRecruitingNCT04737889Phase 2
• Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal CancerRecruitingNCT04703101Phase 1
• 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.RecruitingNCT04689347Phase 1/2
• PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration SamplesRecruitingNCT04683315Phase 2
• A Multicenter Clinical Study on the Safety and Efficacy of CAR-T in the Treatment of Relapsed / Refractory Non Hodgkin's LymphomaRecruitingNCT04666168Not applicable
• Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Plasma Cell TumorsRecruitingNCT04665076Not applicable
• A Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Hodgkin's LymphomaRecruitingNCT04665063Not applicable
• Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal CancerNot yet recruitingNCT04663763Phase 2
• Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction CancerRecruitingNCT04660760Phase 2
• Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant DisordersRecruitingNCT04644016Phase 2
• Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract CancerRecruitingNCT04628767Phase 2/3
• GVHD Prophylaxis With Methotrexate in Haploidentical HCT Using Posttransplant CyclophosphamideRecruitingNCT04622956Phase 1/2

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