Local anesthetics: all 3,142 studies that test it

Page 17 of 32. Open to participants first (432), then studies with results posted, then the rest; newest registration first within each.

• Single-shot Adductor Canal Block With Levobupivacaine and Dexmedetomidine in Total Knee ArthroplastyCompletedNCT04968392Phase 2/3
• Rectal Indomethacin Versus Intraperitoneal Lidocaine for Analgesia After Laparoscopic CholecystectomyCompletedNCT04964180Not applicable
• To Compare the Pulpal Oxygen Saturation Level After Administering Mepivacaine With and Without VasoconstrictorCompletedNCT04947267Phase 2
• Comparison of Different Local Anesthetic Dose in Suprascapular and Axillary Blocks in Shoulder ArthroscopiesCompletedNCT04947007Not applicable
• Erector Spinae Plane Block Impact on Quality of Recovery After Lumbar Spinal DecompressionCompletedNCT04943549Phase 4
• U/s Guided Oblique Subcostal Transversus Abdominis Plane Block Versus Erector Spinae Plane Block as Preemptive AnalgesiaCompletedNCT04941170Phase 4
• Effect of Transversus Abdominis Plane Block With Compound Lidocaine on Pain After Gynecological SurgeryCompletedNCT04938882Not applicable
• The Treatment of Acute Gastrointestinal Injury Via Ultrasound-guided Erector Spinae Plane BlockCompletedNCT04934904Not applicable
• Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis SurgeryCompletedNCT04931433Phase 4
• Continuous vs Liposomal Bupivacaine Interscalene Block for Proximal Humeral Fracture (CLIP)CompletedNCT04928664Phase 4
• Effect of Perioperative Lidocaine on Gastrointestinal Function Recovery After Lumbar Spine Surgery in AdultsStatus unknownNCT04922359Not applicable
• Effect of Pretreatment of Lignocaine Versus Midazolam in Prevention of Etomidate Induced Myoclonus.CompletedNCT04921046Phase 4
• iPACK Block With Dexamethasone For Total Knee ReplacementTerminatedNCT04917055Phase 4
• Ultrasound-guided Erector Spinae Plane BlocksCompletedNCT04916691Early Phase 1
• Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac SurgeryCompletedNCT04916418Phase 4
• HTX-011 in Spinal SurgeryCompletedNCT04911062Phase 2
• Efficacy of Preventive Ketamine on Postoperative PainCompletedNCT04908579Phase 4
• the Effect of Dexmedetomidine and Licodaine on Acute Postoperative Pain in Gynecological LaparoscopyWithdrawnNCT04906889Not applicable
• Xylocaine to Freeze During Unpleasant Nasopharyngeal SwabsCompletedNCT04901065Phase 2/3
• Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement OperationsCompletedNCT04900116Not applicable
• Efficacy of Corticosteroid and Local Anesthetic Injections Patients With Concomitant Pes Anserine BursitisCompletedNCT04887844Not applicable
• Diltiazem Ointment With Lidocaine vs. Nifedipine Ointment With Lidocaine Ointment for Treatment of Chronic Anal FissureStatus unknownNCT04887818Phase 2/3
• Topical Lidocaine Anesthesia for Nasopharyngeal SamplingCompletedNCT04885777Not applicable
• EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies TrialStatus unknownNCT04879004Not applicable
• Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)Active, not recruitingNCT04874038Phase 3
• Effect of Ropivacaine During Popliteal Nerve Block in Foot and Ankle SurgeryStatus unknownNCT04872322Phase 3
• The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular TrappingWithdrawnNCT04868747Not applicable
• Serratus Anterior or Erector Spinae Block for Hybrid Arrhythmia Ablation SurgeryTerminatedNCT04868058Not applicable
• Does a ThoracoLumbar Interfacial Plane (TLIP) Block With Liposomal Bupivacaine Provide TLIP Block in Spinal SurgeryStatus unknownNCT04865211Phase 2
• Efficacy of Hematoma Block on Postoperative Pain After Femoral Intramedullary Rodding: A Randomized TrialCompletedNCT04860856Phase 4
• Sedation for Patients Undergoing Endoscopic Retrograde CholangiopancreatographyCompletedNCT04860167Not applicable
• The Effect of Lidocaine and Benzocaine on Pain and Injection Satisfaction in Peripheral Intravenous Catheter ApplicationCompletedNCT04859738Phase 3
• Lidocaine Gel 2% and Muscle Traction Pain During Squint Surgery in PediatricsCompletedNCT04859062Not applicable
• Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKACompletedNCT04854395Phase 4
• Morphine Versus Ketamine as Adjuvants in Paravertebral BlocksActive, not recruitingNCT04852484Not applicable
• Pilot Study of Liposomal Bupivacaine Redosing in Patients Undergoing Major Gynecologic ProceduresTerminatedNCT04849858Phase 3
• Regional Anesthesia for Totally Awake Upper Limb Surgery in PEDiatric PopulationCompletedNCT04846855Phase 4
• The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular TrappingActive, not recruitingNCT04840511Not applicable
• Analgesia Management in Bariatric SurgeryCompletedNCT04836819Not applicable
• Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.CompletedNCT04835116Phase 4
• Ropivacaine Use in Femoral Nerve Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)Status unknownNCT04834440Phase 4
• Ropivacaine Use in Interscalene Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)Status unknownNCT04833296Phase 4
• ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer SurgeryCompletedNCT04827030Phase 4
• Bupivacaine in TonsillectomyCompletedNCT04825704Phase 3
• Anaesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine With Symptomatic Irreversible PulpitisCompletedNCT04822415Not applicable
• Intrathecal Morphine for Radical Robot Assisted Prostatectomy (TORNADO)CompletedNCT04814745Not applicable
• Trans Abdominis Plane (TAP) Block in Patients With Cesarean SectionStatus unknownNCT04809532Not applicable
• PK/PD Levobupivacaine with and Without Epinephrine After Ultrasound Guided ESP BlockCompletedNCT04799184Phase 4
• Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid InjectionActive, not recruitingNCT04794842Early Phase 1
• Comparison of Lateral and Medial Approaches to Costoclavicular Brachial Plexus Block in PediatricsCompletedNCT04786756Not applicable
• Transversus Abdominis Plane Catheter Following Kidney TransplantationStatus unknownNCT04786470Phase 3
• An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue SurgeriesCompletedNCT04785638Phase 3
• Efficacy and Safety Study of Postsurgical Analgesia With INL-001 in AbdominoplastyCompletedNCT04785625Phase 3
• Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% With Water ExposureCompletedNCT04784728Phase 1
• Dexamethasone Plus Bupivacaine Versus Bupivacaine in Bilateral Trans-incisional Paravertebral Block in Lumbar Spine Surgeries .CompletedNCT04783194Not applicable
• Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in PediatricsCompletedNCT04782778Not applicable
• Ketamine vs Lidocaine in Traumatic Rib FracturesCompletedNCT04781673Phase 4
• Modified TAP (Transverse Abdominis Plane) Block in Colorectal SurgeryCompletedNCT04781075Phase 4
• Effectiveness of Combined Erector Spinae and Pecto-intercostal Fascial Plane Blocks Versus Thoracic Paravertebral Block in Perioperative Pain in Modified Radical MastectomyCompletedNCT04778267Phase 4
• Effectiveness of Saline Water and Lidocaine Injections for the Treatment of Intractable Plantar KeratomaCompletedNCT04777227Not applicable
• Effect of Lidocaine Versus Magnesium on Postoperative Pain in Spine SurgeryStatus unknownNCT04776369Phase 4
• Hip Denervation in Juvenile Idiopathic Arthritis With Hip ArthritisCompletedNCT04775225Phase 3
• Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL ReconstructionStatus unknownNCT04764916Phase 3
• The Significance of Peripheral InputStatus unknownNCT04764045Not applicable
• Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paravertebral Block for Lobectomy: A Prospective, Randomized, Triple-blind StudyStatus unknownNCT04763434Phase 4
• The Optimal Dosage of Ropivacaine for Arthroscopic Knee SurgeryCompletedNCT04759742Early Phase 1
• Comparison Between Platelet-rich Fibrin and Steroid for Intra-articular Injection for Sacroiliac Joint DysfunctionCompletedNCT04757740Phase 4
• Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot SurgeryStatus unknownNCT04751344Phase 4
• Amitriptyline vs GON and SON Blocks in MigraineCompletedNCT04750967Not applicable
• Dexmedetomidine as an Adjuvant to Local Anesthesia in Quadratus Lumborum Block After Cesarean DeliveryCompletedNCT04748224Not applicable
• Peripheral Nerve Injections for CRPSActive, not recruitingNCT04744675Phase 2
• Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial)Status unknownNCT04741880Phase 2/3
• Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff RepairCompletedNCT04737980Phase 4
• Stem Cells vs. Steroids for Discogenic Back PainWithdrawnNCT04735185Not applicable
• Preoperative Analgesia by Infiltration of the Pudendal Nerve Prior to Sacrospinous Ligament SuspensionStatus unknownNCT04733560Not applicable
• Ultrasound Guided Infraclavicular Brachial Plexus Block Using Levo-bupivacaine Alone or Combined With Dexmedetomidine for Hand and Forearm SurgeriesCompletedNCT04729868Not applicable
• Bupivacaine Infiltration and Postoperative PainStatus unknownNCT04728308Early Phase 1
• Stellate Ganglion Block for Major Depressive Disorder.CompletedNCT04727229Phase 4
• Respiratory Impact of LA Volume After IS BlockCompletedNCT04726280Phase 4
• Systemic and Local Levels of Lidocaine During Surgery for the Removal of GlioblastomaCompletedNCT04716699Phase 1
• Effect of Introperative Ketamine and Lidocaine Infusion on Postoperative Opioid Consumption in Posterior Spinal Fusion SurgeryCompletedNCT04711668Not applicable
• Fascia Iliaca Compartment Block Versus Anterior Quadratus Lumborum BlockCompletedNCT04709211Not applicable
• Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological SurgeryCompletedNCT04706897Phase 4
• Effect of Co-administration Lidocaine and Dexmedetomidine on Quality of RecoveryCompletedNCT04706767Not applicable
• Erector Spinae Plane Block With Ropivacaine for Major Upper Abdominal SurgeryStatus unknownNCT04702685Phase 3
• Effect of Different Concentrations of Lidocaine in Relieving Pain in Wide Awake Hand Surgery Using TumescenceCompletedNCT04692896Phase 1
• Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular AnaesthesiaCompletedNCT04691726Phase 4
• Liposomal Bupivacaine Pharmacokinetic Study After Median Sternotomy Incision Infiltration in a Pediatric Cardiac SurgeryTerminatedNCT04685421Phase 1
• Efficacy of CPPLAI in Laparoscopic Sleeve Gastrectomy PatientsCompletedNCT04680923Not applicable
• Stopping Opioid Overuse in Obstetrics to Halt Exposure TrialActive, not recruitingNCT04680221Phase 4
• Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly PatientsCompletedNCT04673812Not applicable
• Regional Anesthesia in Pediatric Orthopaedic PatientsCompletedNCT04669145Phase 2/3
• Postoperative Analgesia With a Catheter Under the Erector Spinae Muscle for Videothoracoscopic Lung SurgeryCompletedNCT04665531Not applicable
• Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy SurgeryCompletedNCT04659057Phase 4
• Intraperitoneal Magnesium Sulphate and Bupivacaine Versus Intravenous Analgesia in Laparoscopic Surgeries in PediatricsCompletedNCT04651556Phase 4
• Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)CompletedNCT04650074Phase 2/3
• REDUCE Trial: Perineural Dexamethasone on Scalp Nerve BlocksCompletedNCT04648358Not applicable
• Compartment Psoas Block Efficacy and SafetyCompletedNCT04648332Not applicable
• Pilot Trial: Comparing Buzzy to Intradermal Lidocaine for Peripheral IV Cannulation in AdultsWithdrawnNCT04647084Phase 4
• Ethyl Chloride for NPWTCompletedNCT04635696Phase 4

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