An interventional study of Levobupivacaine(chirocaine) plus dexmedetomidine(precedex) in Acquired Deformity of Elbow, Forearm and Hand, sponsored by Aswan University Hospital. Completed at 1 site in Egypt. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2021-01-29.
Sponsored by Aswan University Hospital · Not applicable, Interventional, and Other
To evaluate the efficacy of levo-bupivacaine alone and with dexmedetomidine in Ultrasound guided infraclavicular brachial plexus block for hand and forearm surgeries as regard:
Onset of sensory and motor blockade. Duration of sensory and motor blockade.
Analgesic pain scores using the verbal rating scale (VRS) for pain. Duration of analgesia postoperative complications.
Technique for ultrasound guided infraclavicular brachial plexus block:
Preliminary scan
Ultrasound settings
980 studies on the registry are indexed under Congenital Abnormalities; 177 are open to participants now.
This study's enrollment of 60 is above the median of 49 across 491 interventional studies indexed under Congenital Abnormalities.
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Exclusion Criteria:
Group A (20 patients): Anesthesia will be performed with 35 ml of 0.5% levo-bupivacaine plus 1ml normal saline under the guidance of ultrasound for infraclavicular brachial plexus block.
Drug: Levobupivacaine(chirocaine) plus dexmedetomidine(precedex)
Group B (20 patients): Anesthesia will be performed with 35 ml of 0.5% levo-bupivacaine plus 50µg dexmedetomidine under the guidance of ultrasound for infraclavicular brachial plexus block.
Drug: Levobupivacaine(chirocaine) plus dexmedetomidine(precedex)
Group C (20 patients): Anesthesia will be performed with 35 ml of 0.5% levo-bupivacaine plus 100µg dexmedetomidine under the guidance of ultrasound for infraclavicular brachial plexus block.
Drug: Levobupivacaine(chirocaine) plus dexmedetomidine(precedex)
evaluate the efficacy of levo-bupivacaine alone and with dexmedetomidine in Ultrasound guided infraclavicular brachial plexus block for hand and forearm surgeries
Also known as: the efficacy of levo-bupivacaine alone and with dexmedetomidine in Ultrasound guided infraclavicular brachial plexus block for hand and forearm surgeries
Onset time of sensory block in minutes
After the injection of the solution, every patient was checked for the onset of sensory blockade using goose soaked with iced normal saline by the following scale (three-point scale): Grade 0= perceived as normal sensation, Grade 1 = loss of cold sensation (analgesia), Grade 2= loss of sensation of touch (anesthesia).
Time frame: 45 minutes
onset time of motor blockade in minutes using the modified Bromage scale (Three-point scale)
the modified Bromage scale (Three-point scale): Grade 0: Normal motor function, Grade 1: Decreased motor strength with the ability to move the fingers only, Grade 2: Complete motor block with an inability to move the fingers.
Time frame: 24 hours
Duration of sensory block in hours
It's the time from sensory block onset to the time of restoration of sensation at the surgical site
Time frame: 24 hours
Duration of motor block in hours
It's the time from motor block onset to the restoration of global mobility in the hand and the wrist.
Time frame: 24 hours
Visual analog scale (VAS)
the VAS consisted of a straight, vertical 10-cm line; the bottom point represented "no pain" = (0 cm) and the top "the worst pain you ever have" = (10 cm)
Time frame: 24 hours
Postoperative first analgesic request time in hours
was taken from the time of complete sensory block to the request to rescue analgesia when VAS \> 4 cm.
Time frame: 24 hours
Mean blood pressure in mmHg
was measured before the block (0 min) and at 5, 10, 15, 30 min then 1, 2, 3, 6, 12,18and 24 h after the block
Time frame: 24 hours
heart rate in beats / minute
was measured before the block (0 min) and at 5, 10, 15, 30 min then 1, 2, 3, 6, 12,18and 24 h after the block.
Time frame: 24 hours
peripheral oxygen saturation
was measured before the block (0 min) and at 5, 10, 15, 30 min then 1, 2, 3, 6, 12,18and 24 h after the block.
Time frame: 24 hours
This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
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Aswan University Hospital