Antiandrogens: all 479 studies that test it

Page 2 of 5. Open to participants first (92), then studies with results posted, then the rest; newest registration first within each.

• Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate CancerCompletedNCT04736199Phase 3Results posted
• Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate GlandCompletedNCT04530552Phase 2Results posted
• A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for MetastasesCompletedNCT04523207Phase 2Results posted
• Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or EnzalutamideCompletedNCT04335682Phase 2Results posted
• A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland CarcinomaActive, not recruitingNCT04325828Phase 2Results posted
• Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate CancerActive, not recruitingNCT04262154Phase 2Results posted
• A Study Comparing ARB With Radium-223 vs ARB Therapy With Placebo and the Effect Upon Survival for mCRPC PatientsTerminatedNCT04237584Phase 3Results posted
• A Study of Tazemetostat With Enzalutamide or Abiraterone/Prednisone in Participants With Advanced Prostate CancerTerminatedNCT04179864Phase 1/2Results posted
• Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC)TerminatedNCT04157088Phase 2Results posted
• A Study of Apalutamide in Chinese Participants With Non Metastatic Castration Resistant Prostate Cancer (NM-CRPC)CompletedNCT04108208Phase 4Results posted
• An Efficacy and Safety Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Chinese Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)Active, not recruitingNCT04076059Phase 3Results posted
• Erdafitinib and Abiraterone Acetate or Enzalutamide in Treating Patients With Double Negative Prostate CancerTerminatedNCT03999515Phase 2Results posted
• A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following SurgeryActive, not recruitingNCT03809000Phase 2Results posted
• Conventional Androgen Deprivation Therapy (ADT) With or Without Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADTTerminatedNCT03777982Phase 3Results posted
• A Safety and Efficacy Study of Enzalutamide in Indian Patients With Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel-Based ChemotherapyCompletedNCT03641560Phase 4Results posted
• Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen SuppressionCompletedNCT03507608Early Phase 1Results posted
• Apalutamide With or Without Stereotactic Body Radiation in Treating Castration-Resistant Prostate CancerCompletedNCT03503344Phase 2Results posted
• ProSTAR: A Study Evaluating CPI-1205 in Patients With Metastatic Castration Resistant Prostate CancerCompletedNCT03480646Phase 1/2Results posted
• Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single Dose Administration Under Fasting Conditions in Prostate CancerTerminatedNCT03478904Phase 1Results posted
• Apalutamide in Treating Patients With Prostate Cancer Before Radical ProstatectomyActive, not recruitingNCT03412396Phase 2Results posted
• Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE TrialActive, not recruitingNCT03371719Phase 2Results posted
• An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate CancerCompletedNCT03338790Phase 2Results posted
• A Salvage Trial of AR Inhibition With ADT and Apalutamide With Radiation Therapy Followed by Docetaxel in Men With PSA Recurrent Prostate Cancer After Radical Prostatectomy (STARTAR)CompletedNCT03311555Phase 2Results posted
• Systemic and Tumor-Directed Therapy for Oligometastatic Prostate CancerCompletedNCT03298087Phase 2Results posted
• Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate CancerCompletedNCT03279250Phase 2Results posted
• A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate CancerActive, not recruitingNCT03246347Phase 2Results posted
• Apalutamide and Abiraterone Acetate in African American and Caucasian Men With Metastatic Castrate Resistant Prostate CancerCompletedNCT03098836Phase 2Results posted
• A Study of Docetaxel + ARN-509 in Castration-Resistant Prostate CancerTerminatedNCT03093272Phase 2Results posted
• A Study of Definitive Therapy to Treat Prostate Cancer After ProstatectomyCompletedNCT03043807Phase 2Results posted
• A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate CancerCompletedNCT03009981Phase 3Results posted
• A Study to Evaluate Changes in Human Breast Cancer Tissue Following Short-Term Use of DarolutamideCompletedNCT03004534Early Phase 1Results posted
• Preoperative Fulvestrant With or Without Enzalutamide in ER+/Her2- Breast CancerActive, not recruitingNCT02955394Phase 2Results posted
• Fulvestrant Plus Enzalutamide in ER+/Her2- Advanced Breast CancerCompletedNCT02953860Phase 2Results posted
• Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate CancerCompletedNCT02918968Phase 4Results posted
• Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing ProstatectomyCompletedNCT02903368Phase 2Results posted
• Prostate Cancer Intensive, Non-Cross Reactive Therapy (PRINT) for Castration Resistant Prostate Cancer (CRPC)CompletedNCT02903160Phase 2Results posted
• A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomyCompletedNCT02849990Phase 2Results posted
• A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active SurveillanceCompletedNCT02799745Phase 2Results posted
• Darolutamide in Addition to Standard Androgen Deprivation Therapy and Docetaxel in Metastatic Hormone-Sensitive Prostate CancerCompletedNCT02799602Phase 3Results posted
• AASUR in High Risk Prostate CancerCompletedNCT02772588Phase 2Results posted
• Apalutamide and Leuprolide in Intermediate and High-risk Prostate CancerCompletedNCT02770391Phase 2Results posted
• Enzalutamide for Patients With Androgen Receptor Positive Salivary CancersActive, not recruitingNCT02749903Phase 2Results posted
• Apalutamide in Treating Patients With Prostate Cancer Who Are in Active SurveillanceTerminatedNCT02721979Phase 2Results posted
• A Study of Definitive Therapy to Treat Prostate CancerCompletedNCT02716974Phase 2Results posted
• Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast CancerCompletedNCT02689427Phase 2Results posted
• Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate CancerTerminatedNCT02685267Phase 2Results posted
• Enzalutamide, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrioid Endometrial CancerCompletedNCT02684227Phase 2Results posted
• A Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)CompletedNCT02677896Phase 3Results posted
• Bicalutamide With or Without Metformin for Biochemical Recurrence in Overweight or Obese Prostate Cancer PatientsCompletedNCT02614859Phase 2Results posted
• Enzalutamide for Bladder Cancer ChemopreventionTerminatedNCT02605863Phase 2Results posted
• A Study to Assess the Efficacy and Safety of Enzalutamide in Subjects With Advanced Hepatocellular CarcinomaCompletedNCT02528643Phase 2Results posted
• Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate CancerActive, not recruitingNCT02522715Phase 1/2Results posted
• Trial of Radiotherapy With Leuprolide and Enzalutamide in High Risk Prostate CancerTerminatedNCT02508636Phase 2Results posted
• Dexamethasone Prior to Re-treatment With Enzalutamide in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Enzalutamide and DocetaxelTerminatedNCT02491411Not applicableResults posted
• A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPCActive, not recruitingNCT02489318Phase 3Results posted
• Enzalutamide in Treating Patients With Relapsed or Refractory Mantle Cell LymphomaTerminatedNCT02489123Phase 2Results posted
• Cabazitaxel Versus the Switch to Alternative AR-targeted Agent (Enzalutamide or Abiraterone) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients Previously Treated With Docetaxel and Who Rapidly Failed a Prior AR-targeted AgentCompletedNCT02485691Phase 4Results posted
• Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate CancerActive, not recruitingNCT02452008Phase 2Results posted
• A Study of Enzalutamide Re-treatment in Metastatic Castration-resistant Prostate Cancer After Docetaxel and/or Cabazitaxel TreatmentTerminatedNCT02441517Phase 4Results posted
• Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate CancerCompletedNCT02430480Phase 2Results posted
• A Positron Emission Tomography/Computed Tomography (PET/CT) Bone Imaging Study in Patients Receiving Enzalutamide for Castration-Resistant Prostate Cancer (CRPC)CompletedNCT02384382Phase 2Results posted
• Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)Active, not recruitingNCT02319837Phase 3Results posted
• Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder CancerCompletedNCT02300610Phase 1Results posted
• An Asian Study to Evaluate Efficacy and Safety of Oral Enzalutamide in Progressive Metastatic Prostate Cancer ParticipantsCompletedNCT02294461Phase 3Results posted
• A Study to Assess the Benefit of Treatment Beyond Progression With Enzalutamide in Men Who Are Starting Treatment With Docetaxel After Worsening of Their Prostate Cancer When Taking Enzalutamide AloneCompletedNCT02288247Phase 3Results posted
• Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide ResistanceCompletedNCT02286921Phase 2Results posted
• Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate CancerCompletedNCT02278185Phase 2Results posted
• Enzalutamide/Leuprolide +/- Abiraterone/Pred in ProstateCompletedNCT02268175Phase 2Results posted
• An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)Active, not recruitingNCT02257736Phase 3Results posted
• EXTEND Exercise TrialCompletedNCT02256111Phase 2Results posted
• Randomized Salvage Radiation Therapy Plus Enzalutamide Post ProstatectomyCompletedNCT02203695Phase 2Results posted
• Efficacy and Safety Study of Darolutamide (ODM-201) in Men With High-risk Non-metastatic Castration-resistant Prostate CancerCompletedNCT02200614Phase 3Results posted
• Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious DistressCompletedNCT02196506Phase 3Results posted
• A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate CancerCompletedNCT02116582Phase 4Results posted
• Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide TherapyCompletedNCT02099864Phase 2Results posted
• A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) Metastatic or Locally Advanced Breast CancerCompletedNCT02091960Phase 2Results posted
• RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)CompletedNCT02090114Phase 2Results posted
• Enzalutamide and Hormone Therapy Before, During, and After Radiation for High Risk Localized Prostate CancerCompletedNCT02064582Phase 2Results posted
• LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate CancerCompletedNCT02058706Phase 2Results posted
• Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)CompletedNCT02057939Phase 2Results posted
• Enzalutamide + External Beam Rt For ProstateCompletedNCT02028988Phase 2Results posted
• Efficacy and Safety Study of Enzalutamide in Combination With Exemestane in Patients With Advanced Breast CancerCompletedNCT02007512Phase 2Results posted
• Safety and Efficacy Study of Enzalutamide in Patients With Nonmetastatic Castration-Resistant Prostate CancerCompletedNCT02003924Phase 3Results posted
• Safety Study of Continued Enzalutamide Treatment In Prostate Cancer PatientsCompletedNCT01995513Phase 4Results posted
• A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate CancerCompletedNCT01981122Phase 2Results posted
• A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With EnzalutamideCompletedNCT01977651Phase 4Results posted
• Enzalutamide in Patients With Androgen Receptor Positive (AR+) Ovarian, Primary Peritoneal or Fallopian Tube Cancer and One, Two or Three Prior TherapiesCompletedNCT01974765Phase 2Results posted
• Enzalutamide With or Without Abiraterone and Prednisone in Treating Patients With Castration-Resistant Metastatic Prostate CancerActive, not recruitingNCT01949337Phase 3Results posted
• A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate CancerActive, not recruitingNCT01946204Phase 3Results posted
• Study of Enzalutamide in Patients With Castration-resistant Prostate CancerCompletedNCT01942837Phase 2Results posted
• Enzalutamide in Patients With High-risk Prostate CancerCompletedNCT01927627Phase 2Results posted
• Safety and Efficacy Study of Enzalutamide in Patients With Advanced, Androgen Receptor-Positive, Triple Negative Breast CancerCompletedNCT01889238Phase 2Results posted
• Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS WomenCompletedNCT01889199Phase 2Results posted
• Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate CancerCompletedNCT01875250Phase 2Results posted
• Enzalutamide With or Without Vaccine Therapy for Advanced Prostate CancerCompletedNCT01867333Phase 2Results posted
• The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate CancerCompletedNCT01790126Phase 2Results posted
• Safety and Efficacy Study of Enzalutamide Versus Bicalutamide in Men With Prostate CancerCompletedNCT01664923Phase 2Results posted
• A Study to Determine Safety and Tolerability of Enzalutamide (MDV3100) in Combination With Abiraterone Acetate in Bone Metastatic Castration-Resistant Prostate Cancer PatientsCompletedNCT01650194Phase 2Results posted
• Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast CancerCompletedNCT01597193Phase 1Results posted
• Safety and Tolerability Study of MDV3100 in Combination With Docetaxel in Men With Advanced Prostate CancerCompletedNCT01565928Phase 1Results posted

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