Trypanosomiasis clinical trials
The registry lists 31 studies for Trypanosomiasis across more than 10 countries. 2 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-08-27.
Status
- Completed
- 22
- Terminated
- 3
- Status unknown
- 2
- Withdrawn
- 2
- Recruiting
- 1
- Not yet recruiting
- 1
Phase
- Phase 3
- 13
- Phase 2
- 10
- Phase 1
- 6
- Phase 4
- 1
Where
- Congo, The Democratic Republic of the
- 11
- Congo
- 5
- Guinea
- 4
- France
- 4
- Côte D'Ivoire
- 3
- Uganda
- 3
Who runs them
Drugs for Neglected Diseases (16) · Institut de Recherche pour le Developpement (4) · Institute of Tropical Medicine, Belgium (3) · Immtech Pharmaceuticals, Inc (2) · Epicentre (2) · University Hospital, Geneva (1) · Population Health Research Institute (1) · Universidad Autónoma de Bucaramanga (1)
Studies
Recruiting first, then most recently updated. Showing 31 of 31 — search for more.
- Stop Transmission of Gambiense Human African TrypanosomiasisRecruitingNCT07789743Phase 31 country
- Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)Not yet recruitingNCT06356974Phase 3
- Safety and Tolerability Study of Acoziborole in g-HAT Seropositive SubjectsCompletedNCT05256017Phase 2/32 countries
- Fexinidazole in Human African Trypanosomiasis Due to T. b. RhodesienseCompletedNCT03974178Phase 2/32 countries
- Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any StageCompletedNCT03025789Phase 32 countries
- Prospective Evaluation of the Specificity of Serological Tests for Human African TrypanosomiasisCompletedNCT05466630Not applicable2 countries
- Screen and Treat Implementation for HAT ControlWithdrawnNCT05645822
- Prospective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum MalariaWithdrawnNCT03394976
- Assessment of Recombinant HAT-RDT SpecificityCompletedNCT056376321 country
- DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and DextromethorphanCompletedNCT05947604Phase 11 country
- Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP3 Post Elimination MonitoringCompletedNCT04099628Not applicable3 countries
- ADME Study of Acoziborole in Healthy SubjectsCompletedNCT04270981Phase 11 country
- Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case DetectionCompletedNCT03356665Not applicable3 countries
- Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cureCompletedNCT03112655Not applicable1 country
- Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal StudyCompletedNCT02169557Phase 2/31 country
- Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal StudyCompletedNCT02184689Phase 2/31 country
- BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' DiseaseCompletedNCT00123916Phase 35 countries
- Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2CompletedNCT01685827Phase 2/33 countries
- CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)Status unknownNCT02369978Phase 2/31 country
- Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the FexinidazoleCompletedNCT00982904Phase 11 country
- Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With FoodTerminatedNCT01483170Phase 11 country
- Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)CompletedNCT01766830Not applicable4 countries
- Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African TrypanosomiasisCompletedNCT00146627Phase 32 countries
- Bioequivalence Study - Reference Clinical Fexinidazole Tablet Versus Proposed Market FormulationCompletedNCT02571062Phase 11 country
- Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158CompletedNCT01533961Phase 11 country
- Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas DiseaseStatus unknownNCT02498782Phase 21 country
- Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic PhaseCompletedNCT00906880Phase 41 country
- Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00803933Phase 21 country
- A Trial of DB289 for the Treatment of Stage I African TrypanosomiasisCompletedNCT00802594Phase 22 countries
- Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, UgandaTerminatedNCT00489658Phase 2/31 country
- Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African TrypanosomiasisTerminatedNCT00330148Phase 31 country