Status Asthmaticus clinical trials
The registry lists 35 studies for Status Asthmaticus across more than 10 countries. 1 are recruiting or about to start. 31 of them are mainly about Status Asthmaticus (how this is decided). Per ClinicalTrials.gov, last updated 2026-08-12.
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Who runs them
Southern Illinois University (2) · Northwell Health (2) · Connecticut Children's Medical Center (2) · Erasmus Medical Center (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Corrie Fletcher (1) · Akron Children's Hospital (1) · Boston Medical Center (1)
What is being tested here
Drugs under test in Status Asthmaticus studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Methylprednisolone | 1 | 0 | 1 |
| Montelukast | 0 | 2 | 4 |
| Dexamethasone | 0 | 0 | 2 |
| Magnesium Sulfate | 0 | 0 | 2 |
| Ipratropium | 0 | 0 | 1 |
| Budesonide | 0 | 1 | 1 |
| Terbutaline | 0 | 0 | 1 |
| Ketamine | 0 | 1 | 1 |
Drug classes tested here Corticosteroids 1 open
Who these studies take
Of the 1 Status Asthmaticus studies recruiting now, 0 (0%) set no upper age limit and 1 (100%) stop at 75 or younger. 1 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (100%) | 1 (100%) |
| 18 | 0 (0%) | 0 (0%) |
| 30 | 0 (0%) | 0 (0%) |
| 40 | 0 (0%) | 0 (0%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 35 studies, recruiting or not: 97% stop at 75 or younger and 94% at 65; 89% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 35 of 35. search them.
- Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical AsthmaRecruitingNCT07455396Phase 21 country
- IV DEXAMETHASONE VS. METHYLPREDNISOLONE IN CHILDREN WITH SEVERE ASTHMA EXACERBATIONCompletedNCT07731217Phase 41 country
- Treating Exacerbations of Asthma With Oral Montelukast in ChildrenCompletedNCT05819541Phase 21 country
- The Role of Ketamine as an Adjuvant Therapy for Children With Acute Status AsthmaticusWithdrawnNCT03338205Phase 3
- B2-Adrenergic Receptor PolymorphismsCompletedNCT002797861 country
- High Flow Nasal Cannula in Children With Status AsthmaticusCompletedNCT03157102Not applicable1 country
- Different Doses of Nebulized Magnesium Sulphate in Status AsthmaticusCompletedNCT04929626Phase 11 country
- NiPPV in the Treatment of Acute Asthma ExacerbationsWithdrawnNCT03219736Not applicable1 country
- BPAP in Pediatric Asthma Pilot StudyWithdrawnNCT04656587Not applicable
- Pilot Simulation RCT of Telemedical Support for ParamedicsCompletedNCT03742167Not applicable1 country
- Intramuscular Epinephrine as an Adjunctive Treatment for Severe Pediatric Asthma ExacerbationCompletedNCT01705964Phase 41 country
- Comparison of Albuterol for Status AsthmaticusTerminatedNCT02966184Phase 41 country
- Status Asthmaticus on the PICU; Intravenous SalbutamolCompletedNCT03493503Phase 41 country
- Steroids in Children Hospitalized With AsthmaTerminatedNCT02780479Phase 41 country
- Status Asthmaticus on the Intensive Care Prospective - STATIC PROCompletedNCT029367781 country
- Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status AsthmaticusCompletedNCT02872597Phase 11 country
- Optimizing Vitamin D Status in Children With Wheeze / Asthma (OPTIVIT)CompletedNCT02880930Not applicable1 country
- Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.TerminatedNCT01025648Phase 1/21 country
- Bilevel Positive Airway Pressure (BiPAP) for the Treatment of Moderate to Severe Acute Asthma ExacerbationsWithdrawnNCT02347462Not applicable1 country
- HFCWO in Hospitalized Asthmatic ChildrenCompletedNCT00722020Not applicable1 country
- Pleth Variability and Asthma Severity in ChildrenCompletedNCT023022611 country
- A Prospective Trial of BiPAP Administration vs. Non-positive Pressure Therapy for Pediatric Status AsthmaticusWithdrawnNCT02539420Not applicable
- Extra-fine Formoterol/Beclomethasone in Asthmatic CrisisStatus unknownNCT02345993Phase 41 country
- Effectiveness and Cost Study Comparing Two Ways to Deliver Albuterol for the Treatment of Asthma in the HospitalCompletedNCT00623688Not applicable1 country
- Early Noninvasive Positive Pressure Ventilation in Children With Status AsthmaticusWithdrawnNCT01188473Phase 11 country
- Non Invasive Positive Pressure Ventilation in Status AsthmaticusWithdrawnNCT01403428Phase 21 country
- Compare Efficacy Nebulized and Intravenous Magnesium Sulphate in Thai ChildrenStatus unknownNCT02112305Not applicable1 country
- The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency RoomCompletedNCT01524198Phase 2/31 country
- Evaluation Montelukast in the Treatment of Status AsthmaticusStatus unknownNCT01770899Not applicable1 country
- Trial of Terbutaline for the Treatment of Status Asthmaticus in ChildrenCompletedNCT00124995Phase 41 country
- Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of AsthmaTerminatedNCT00683449Phase 21 country
- Heliox-Powered Albuterol Therapy in the Treatment of Children Admitted With Acute Asthma ExacerbationTerminatedNCT00410150Phase 21 country
- Montelukast With Status Asthmaticus, Ages 6-18Status unknownNCT00494572Phase 2/31 country
- Montelukast With Status Asthmaticus, Ages 2-5Status unknownNCT00491790Phase 2/31 country
- Intravenous Terbutaline in Severe Status AsthmaticusStatus unknownNCT007505681 country