An interventional study of isotonic magnesium sulphate and 50% magnesium sulphate in Acute Severe Asthma, sponsored by Queen Sirikit National Institute of Child Health. Status unknown at 1 site in Thailand. Open to participants aged 2 Years to 15 Years. Per ClinicalTrials.gov, last updated 2014-11-18.
Sponsored by Queen Sirikit National Institute of Child Health · Not applicable, Interventional, and Treatment
The purpose of this study is to determine whether nebulized magnesium sulphate is effective in the treatment of acute severe asthma when comparison with intravenous magnesium sulphate
Intervention: At randomization eligible patients were allocated to receive 2.5ml of isotonic magnesium sulphate (150 mg,245 mmol/L) on three occasional at 20 minutes interval or standard treatment 50 mg/kg intravenous magnesium sulphate. The asthma severity score was record at 0,20,40,60,120,180,240 minutes post randomization. Adverse event were assessed at each assessment point. Patients were followed up until discharge from hospital to collect secondary outcome data.
3,921 studies on the registry are indexed under Asthma; 507 are open to participants now.
This study's planned enrollment of 40 is below the median of 83 across 2,752 interventional studies indexed under Asthma.
Browse Asthma studies →Queen Sirikit National Institute of Child Health is the lead sponsor of 7 studies on the registry; none are open to participants now.
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Exclusion Criteria:
2.5 ml of isotonic magnesium sulphate (150 mg, 245 mmol/L) on three occasional at 20 minutes interval
Drug: isotonic magnesium sulphate
magnesium sulphate 50mg/kg/dose intravenous drip in 20 minutes for one dose
Drug: 50% magnesium sulphate
2.5 ml of isotonic magnesium sulphate (150 mg, 245 mmol/L) NB on three occasional at 20 minutes interval
Also known as: magnesium sulfate
magnesium sulphate 50mg/kg/dose intravenous drip in 20 minutes for one dose
Also known as: magnesium sulfate
Asthma severity score
Time frame: 60 minute
Length of stay in the hospital
Time frame: within 2 weeks
This study is status unknown, as verified in Nov 2014. You cannot join it, but the record below documents what was studied.
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Queen Sirikit National Institute of Child Health