Sexual Infantilism clinical trials

The registry lists 23 studies for Sexual Infantilism across more than 10 countries. 5 are recruiting or about to start. 14 of them are mainly about Sexual Infantilism (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.

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Status

Completed: 12
Recruiting: 3
Active, not recruiting: 3
Withdrawn: 2
Not yet recruiting: 1
Status unknown: 1

Phase

Phase 2: 10
Phase 3: 6
Phase 1: 2
Phase 4: 2
Early Phase 1: 1

Where

United States: 14
United Kingdom: 4
Canada: 3
France: 2
Germany: 1
Netherlands: 1

Who runs them

Rhythm Pharmaceuticals, Inc. (7) · Seattle Children's Hospital (2) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Grace Kim (1) · Children's Hospitals and Clinics of Minnesota (1) · Seoul National University Hospital (1) · University Hospital, Bordeaux (1) · Huashan Hospital (1)

What is being tested here

Drugs under test in Sexual Infantilism studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Setmelanotide	1	3	4
Bivamelagon	1	0	2
Semaglutide	1	1	1
Tirzepatide	1	0	1
Liraglutide	1	0	1
Exenatide	0	2	5
Qsymia	0	0	1
Melatonin	0	0	1
Oxytocin	0	0	1
Diazoxide	0	0	1

Drug classes tested here GLP-1 receptor agonists 3 open

Coming up

3phase 3 studies under way

2studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 2, phase 3 first

Mar 2027A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756) · Phase 3 · Rhythm Pharmaceuticals, Inc.
May 2027A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment · Rhythm Pharmaceuticals, Inc.

Who these studies take

Of the 3 Sexual Infantilism studies recruiting now, 2 (67%) set no upper age limit and 1 (33%) stop at 75 or younger. 1 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 3
Age	Women	Men
10	1 (33%)	1 (33%)
18	2 (67%)	2 (67%)
30	2 (67%)	2 (67%)
40	2 (67%)	2 (67%)
50	2 (67%)	2 (67%)
65	2 (67%)	2 (67%)
75	2 (67%)	2 (67%)
85	2 (67%)	2 (67%)

Across all 23 studies, recruiting or not: 65% stop at 75 or younger and 61% at 65; 61% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 14, 2026.

Results posted1

A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic ObesityOct 30, 2026NCT06046443

Studies

Recruiting first, then most recently updated. Showing 23 of 23. search them.