Sarcoma: all 1,691 studies

Page 8 of 17. Open to participants first (393), then studies with results posted, then the rest; newest registration first within each.

• The Clinical Application Value of SPECT Imaging Targeting LRRC15 in Malignant TumorsCompletedNCT07651020
• Multicentre Retrospective Cohort Study of Palliative Care Pathways in Patients Who Died From SarcomaCompletedNCT07532668
• CD70.CAR for CD70+ Lymphoma, Myeloma and Solid TumorsWithdrawnNCT07297160Phase 1
• Machine Learning Applied to EHRs Data of Patients With SarcomaCompletedNCT07215728
• Phase I Study of Safety and Feasibility of Transarterial Embolization of Incurable Hypervascular Pediatric Soft Tissue SarcomasWithdrawnNCT07136571Not applicable
• Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic CancersActive, not recruitingNCT07118176Phase 1
• A Study to Determine the Safety and Effectiveness of the Investigational Cellular Therapy GCAR1 in a Patient With Alveolar Soft Part SarcomaActive, not recruitingNCT07104682Early Phase 1
• Saving Limbs After Cancer: Blood Vessel and Soft Tissue Reconstruction Following Sarcoma Surgery in the LegsCompletedNCT07093320
• Biopsy Needle Size in Soft Tissue SarcomaCompletedNCT07066774Not applicable
• Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue SarcomasSuspendedNCT07052383Phase 1
• Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue SarcomaSuspendedNCT06968988Phase 1
• Β3-adrenoreceptor As Prognostic Marker in Neuroblastoma and Ewing SarcomaCompletedNCT06851221Not applicable
• Exploring the Expression Level of Cadherin 6 Protein (CDH6) in Primary Malignant Bone Tumor Specimens and Its Clinical Application in Prognosis AssessmentActive, not recruitingNCT06850506
• CAR T Therapy With GCAR1 for Relapsed Alveolar Soft Part SarcomaActive, not recruitingNCT06813417Early Phase 1
• The Safety and Efficacy of Combined Microwave Ablation During Limb-sparing Surgery in High-risk Soft Tissue Sarcoma PatientsCompletedNCT06802510Not applicable
• The Exploration of OX40 (CD134) Expression Levels in Sarcoma Specimens and Its Clinical Application in Prognosis DeterminationActive, not recruitingNCT06751251
• Prehabilitation in Childhood Soft Tissue or Bone SarcomasActive, not recruitingNCT06743958Not applicable
• Distinguishing Retroperitoneal Fibrosis and Sarcoma from Other Retroperitoneal Diseases Via RadiomicsActive, not recruitingNCT06741423
• Functional and Structural Outcomes Following Childhood Bone or Soft Tissue Sarcomas of the Lower ExtremityActive, not recruitingNCT06737172
• Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue SarcomaWithdrawnNCT06670976Phase 1
• Neoadjuvant Intralesional Injection of Talimogene LaherparepvecActive, not recruitingNCT06660810Phase 2
• Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 2
• Treatment Outcomes of Retroperitoneal SarcomaActive, not recruitingNCT06612671
• Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult ParticipantsTerminatedNCT06566092Phase 1
• Descriptive Cohort of French Patients Treated With Carbonetherapy Since October 2010 Outside PHRC-ETOILECompletedNCT06535997
• Cardiotoxic Effects of Chemotherapy in Patients With Sarcomas: A Two and Three-dimensional Echocardiographic Speckle Tracking Imaging StudyTerminatedNCT06511388
• A Phase 2 Study Using Aliya PEF Plus Pembro for SarcomaWithdrawnNCT06494787Phase 2
• Risk Stratification Oriented Treatment of Pediatric Ewing Sarcoma: a Prospective Multicenter Cohort StudyActive, not recruitingNCT06451302Not applicable
• Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient MalignanciesActive, not recruitingNCT06444880Phase 2
• A Study Of Naxitamab , Granulocyte Macrophage Colony Stimulating Factor For Patients With Relapsed /Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory NeuroblastomaCompletedNCT06438614Phase 2
• PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STSCompletedNCT06413095Early Phase 1
• Survival and Prognostic Factors of Primary Retroperitoneal Sarcomas After Surgery: a Single-center ExperienceCompletedNCT06396962
• Blood and Tissue Extraction for Immunological Examinations During Neoadjuvant Therapy of Soft Tissue SarcomasActive, not recruitingNCT06385288Not applicable
• Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue SarcomaWithdrawnNCT06370871Phase 3
• A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid TumorsTerminatedNCT06336148Phase 1
• Outcomes Comparison Between Bone Resection and Subperiosteal Dissection for Specific Type of Soft Tissue SarcomaCompletedNCT06317480
• A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or DeletionsActive, not recruitingNCT06308419Phase 1
• YASU Research Registry: For Young Adults With CancerTerminatedNCT06275854
• Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES)WithdrawnNCT06252727Phase 1
• Neoadjuvant Lurbinectedin and Preoperative Radiation for Treating Soft Tissue SarcomasWithdrawnNCT06217536Phase 1/2
• Metastatic or Refractory Soft Tissue Sarcomas and Metronomic Cyclophosphamide: Further Assessment of Efficacy and SafetyCompletedNCT06216990
• SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GISTActive, not recruitingNCT06208748Phase 2
• Fruquintinib-based Treatment for Refractory Bone and Soft Tissue Sarcomas After Several Lines of TKIs' ResistanceCompletedNCT06202599
• WeCanManage. An mHealth Self-management ToolCompletedNCT06185738Not applicable
• Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer SurvivorsCompletedNCT06171945Not applicable
• Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO TrialActive, not recruitingNCT06128863Phase 2
• Study Evaluating Pembrolizumab +/- Olaparib in TLS Positive Selected Resectable STS Followed by Adjuvant PembrolizumabWithdrawnNCT06116578Phase 2
• Efficacy and Safety Study of Cardunilizumab in Soft Tissue SarcomaActive, not recruitingNCT06114173Early Phase 1
• Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid StructuresWithdrawnNCT06084689Phase 2
• Novel Applications for Sarcoma AssessmentCompletedNCT06073314
• Prospective Study to Evaluate Patient Reported Outcomes (PRO) During Rechallenge With Trabectedin in Sarcoma PatientsTerminatedNCT06050434
• A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue SarcomaSuspendedNCT05941325Phase 2
• Preoperative Moderately Fractionated IMRT for Locally Extremity or Trunk Sarcoma (SPARE-03)CompletedNCT05938374Phase 2
• A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated LiposarcomaActive, not recruitingNCT05886634Phase 2
• Evaluation of Autologous Natural Killer Cell Activity in Primary Cancer Cell CulturesWithdrawnNCT05869994
• A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid TumorsCompletedNCT05864144Phase 1/2
• Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue SarcomaCompletedNCT05858710Phase 1
• Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue SarcomaActive, not recruitingNCT05836571Phase 2
• A Checklist (Advanced Care Planning) for The Assessment of Mobility Needs in Patients With SarcomaCompletedNCT05835154Not applicable
• An Adequate Cost Effective Follow Up Protocol For Bone and Soft Tissue SarcomasCompletedNCT05827458
• Study Evaluating the Safety and Efficacy of MEDI5752 in Combination With Stereotactic Radiotherapy in Patients With Metastatic SarcomaCompletedNCT05821231Phase 1
• Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision TherapeuticsTerminatedNCT05819827
• Low-dose Computer Tomography in Follow-up of Soft Tissue SarcomasCompletedNCT05813808Not applicable
• Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue SarcomaTerminatedNCT05813327Phase 1
• A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid TumorsActive, not recruitingNCT05812027
• Phase I/II of LB-100 Plus Doxorubicin vs. Doxorubicin Alone in First Line of Advanced Soft Tissue SarcomasActive, not recruitingNCT05809830Phase 1/2
• Study on Dynamic CtDNA Analysis in Pediatric Soft Tissue SarcomaStatus unknownNCT05778955
• Feasibility Trial of Preoperative 5-Day Hypofractionated Radiotherapy for Primary Soft Tissue SarcomaActive, not recruitingNCT05776667Not applicable
• Anrotinib Hydrochloride Combined With Adriamycin for Neoadjuvant Treatment of High-grade Soft Tissue SarcomaStatus unknownNCT05747521Not applicable
• The Value of a Risk Prediction Tool (PERSARC) for Effective Treatment Decisions of Soft-tissue Sarcomas PatientsActive, not recruitingNCT05741944Not applicable
• Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)TerminatedNCT05712694Phase 3
• A Clinical Trial of KVA12123 [TBS-2025] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)CompletedNCT05708950Phase 1/2
• Pilot Study to Determine Pro-Inflammatory Cytokine Kinetics During Immune Checkpoint Inhibitor TherapyCompletedNCT05707286
• PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision MedicineCompletedNCT05697198
• Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STSActive, not recruitingNCT05688280Phase 1/2
• Irinotecan and Anlotinib for Epithelioid SarcomaWithdrawnNCT05656222Not applicable
• TAS-116 Plus Palbociclib in Breast and Rb-null CancerWithdrawnNCT05655598Phase 1
• Undifferentiated Embryonal Sarcoma of the Liver: Evaluation of the Relapse Profile According to the Therapies AdministeredCompletedNCT05640960
• Influence of Nutritional Status on Oncologic and Operative Outcome in Patients Operated for Retroperitoneal SarcomaCompletedNCT05631379
• A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone SarcomaActive, not recruitingNCT05621668Phase 1
• Anlotinib and Radiotherapy in Resectable Soft Tissue SarcomaStatus unknownNCT05602415Phase 2
• The Effects of Observer Presence and Type on Patients' Perception of Exercise in Patients With Soft Tissue SarcomaStatus unknownNCT05596565Not applicable
• Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable CancersWithdrawnNCT05582031Phase 2
• 89Zr-girentuximab for PET Imaging of CAIX Positive Solid TumorsTerminatedNCT05563272Phase 2
• An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue SarcomasCompletedNCT05560009
• Phase II Study of TAEST16001 in Soft Tissue SarcomaTerminatedNCT05549921Phase 2
• A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid TumorsCompletedNCT05538572Phase 1
• PSMA Expression and PSMA PET Imaging in Soft Tissue Sarcomas and Urothelial Cell CarcinomasCompletedNCT05522257Not applicable
• A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNAActive, not recruitingNCT05515575Phase 2
• Chiauranib for Advanced or Unresectable Soft Tissue Sarcoma(STS)CompletedNCT05497843Phase 2
• Immunotherapy Combined With Radiotherapy for Metastatic SarcomaActive, not recruitingNCT05488366Early Phase 1
• YH001 Plus Envafolimab With or Without Doxorubicin in Patients With Advanced or Metastatic SarcomaActive, not recruitingNCT05448820Phase 1/2
• Adjuvant Versus Neo-adjuvant Radiotherapy in Patients With Resectable Soft Tissue Sarcoma in Extremities : Wound ComplicationsActive, not recruitingNCT05442333Not applicable
• FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)TerminatedNCT05432193Phase 1
• Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption ApproachCompletedNCT05420727Phase 1
• Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def TumorsActive, not recruitingNCT05407441Phase 1/2
• A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null TumorsTerminatedNCT05355753Phase 1
• Neoadjuvant Short-course Hypofractionated PBT for Non-metastatic RPSWithdrawnNCT05302570Phase 2
• A Study of LVGN6051 Combined With Anlotinib in Patient With Soft Tissue SarcomaCompletedNCT05301764Phase 1/2
• Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient TumorsActive, not recruitingNCT05286801Phase 1/2

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