Retinal Dystrophies: all 60 studies
Page 1 of 1. Open to participants first (20), then studies with results posted, then the rest; newest registration first within each.
- Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Gene Therapy (SPVN20) in Subjects With Rod-Cone DystrophyRecruitingNCT07807111Phase 1/2
- Safety and Efficacy Study of PUMCH-E111 Injection in Subjects With RLBP1 Related Inherited Retinal DystrophyRecruitingNCT07656753Early Phase 1
- Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual PerformanceRecruitingNCT07548944
- Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic QualityEnrolling by invitationNCT07529041Not applicable
- Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)RecruitingNCT07502664
- Natural History Study of Inherited Retinal DiseasesRecruitingNCT07085533
- A Study of LX107 Gene Therapy in AIPL1-IRD PatientsRecruitingNCT07063030Early Phase 1
- Functional Assessments in Vision ImpairmentNot yet recruitingNCT06908161
- Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome PatientsRecruitingNCT06395285Phase 1
- Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal DegenerationRecruitingNCT06375239
- The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal DegenerationRecruitingNCT06319872Phase 1
- Coloured-light in Retinitis Pigmentosa.Not yet recruitingNCT06224114Not applicable
- Gene Therapy in Subjects With Biallelic RPE65 Mutation-associated Retinal DystrophyRecruitingNCT05858983Phase 1/2
- Disulfiram for Treatment of Retinal DegenerationRecruitingNCT05626920Phase 1/2
- EyeConic: Qualification for Cone-OptogeneticsRecruitingNCT05294978
- VIsual Cerebral ConnecTivity On Functional Magnetic Resonance Imaging in Patients With Hereditary REtinal DystrophiesRecruitingNCT04648124
- Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.RecruitingNCT03990727
- Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable
- Evaluation of Objective Perimetry Using Chromatic Multifocal PupillometerRecruitingNCT02014389
- Familial Mediterranean Fever and Related Disorders: Genetics and Disease CharacteristicsRecruitingNCT00001373
- Optical Head-Mounted Display Technology for Low Vision RehabilitationCompletedNCT02983305Not applicableResults posted
- Personalized Antisense Oligonucleotide Therapy for a Single Participant With PRPH2 Mutation Associated With Retinal DystrophyActive, not recruitingNCT07177196Phase 1/2
- Efficacy and Safety of LX101 for Inherited Retinal Dystrophy Associated With RPE65 MutationsActive, not recruitingNCT07054632Phase 3
- A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001Active, not recruitingNCT06852963Phase 1/2
- MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)CompletedNCT06455826Phase 1
- Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis PigmentosaActive, not recruitingNCT06323772
- Fellow-eye Study (FE) of LX101 in Subjects With Inherited Retinal DystrophyActive, not recruitingNCT06212297Phase 1/2
- Safety and Tolerability of LX101 for Inherited Retinal Dystrophy Associated With RPE65 MutationsActive, not recruitingNCT06196827Phase 1
- SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)CompletedNCT06177977Not applicable
- Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE StudyActive, not recruitingNCT06162585
- Non-interventional Long Term Follow-up Study of Participants Previously Enrolled in the STARLIGHT StudyActive, not recruitingNCT06048185
- SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy SubjectsCompletedNCT05902962Phase 1
- Observational Study to Assess the Reliability and Validity of the MLYMT and MLSDTCompletedNCT05820100
- Promising ROd-cone DYstrophy Gene therapYActive, not recruitingNCT05748873Phase 1/2
- Natural History of PRPF31 Mutation-Associated Retinal DystrophyActive, not recruitingNCT05573984
- Safety and Effects of a Single Intravitreal Injection of vMCO-010 Optogenetic Therapy in Subjects With Stargardt DiseaseCompletedNCT05417126Phase 2
- High Resolution Optical Coherence TomographyStatus unknownNCT05130385
- Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]CompletedNCT04945772Phase 2
- An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.Status unknownNCT04855045Phase 2/3
- BEOVU in the Treatment of Dystrophy-related Macular Neovascular DegenerationStatus unknownNCT04690062Phase 4
- Study of New Mutations in Cone DisordersTerminatedNCT04658251
- Oral Metformin for Treatment of ABCA4 RetinopathyActive, not recruitingNCT04545736Phase 1/2
- Study of Efficacy and Safety of Voretigene Neparvovec in Japanese Patients With Biallelic RPE65 Mutation-associated Retinal DystrophyCompletedNCT04516369Phase 3
- Establishment of the National Registry for Inherited Retinal Dystrophy in IranStatus unknownNCT04131400
- A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO GeneActive, not recruitingNCT04123626Phase 1/2
- iPS Cells of Patients for Models of Retinal DystrophiesCompletedNCT03853252Not applicable
- Dual Wavelength OCTCompletedNCT03843840
- Intravitreal Ranibizumab (Lucentis®) in the Treatment of Non-leaking Macular Cysts in Retinal DystrophyCompletedNCT03763227Phase 2
- Multi-center Observation of the Natural Course of Inherited Retinal DystrophiesStatus unknownNCT03691168
- Prospective Analysis of "Genotype-phenotype" Correlations Observed in a Large Cohort of Patients With Hereditary Retinal Dystrophies - GEPHIRDTerminatedNCT03662386
- Study on the Effects of Mutations Under Inherited Retinal Disease in KoreanCompletedNCT03613948
- Performance of Long-wavelength Autofluorescence ImagingCompletedNCT03592017Not applicable
- Natural History of the Progression of Choroideremia StudyCompletedNCT03359551
- Safety and Efficacy Study in Patients With Retinitis Pigmentosa Due to Mutations in PDE6B GeneTerminatedNCT03328130Phase 1/2
- Stem Cell Ophthalmology Treatment StudyStatus unknownNCT01920867Not applicable
- Novel Quantification Methods for Fluorescence to Detect Progression in Stargardt DiseaseTerminatedNCT01676766
- Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General DiseasesCompletedNCT01546181
- The Natural History of Mucolipidosis Type IVTerminatedNCT01067742
- Safety Study of RPE65 Gene Therapy to Treat Leber Congenital AmaurosisCompletedNCT00643747Phase 1/2
- Genetic Study of Patients Suffering From Congenital Amaurosis of Leber or From an Early Severe Retinal DystrophyCompletedNCT00422721Not applicable