Rectal Fistula clinical trials
The registry lists 169 studies for Rectal Fistula across more than 10 countries. 45 are recruiting or about to start. 147 of them are mainly about Rectal Fistula (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
Mansoura University (11) · Assiut University (8) · Cook Group Incorporated (5) · University of Southern Denmark (4) · Region Skane (4) · Zhen Jun Wang (3) · Zagazig University (3) · Sixth Affiliated Hospital, Sun Yat-sen University (3)
What is being tested here
Drugs under test in Rectal Fistula studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Effect of Platelet-Rich Plasma Injection on Wound Healing After Fistulotomy for Simple Anal Fistula Randomized Controlled Trial (RCT) · Assiut University
- Dec 2026E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas · Weill Medical College of Cornell University
- Dec 2026Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's Disease · CryoCord Sdn Bhd
- Jan 2027Determining the Effect of Education Given to Patients Undergoing Outpatient Anal Fistula Surgery · Muğla Sıtkı Koçman University
- Jan 2027FISTULA-RFA Trial: Radiofrequency Ablation for Perianal Fistula · Korea University Ansan Hospital
- Feb 2027Study Evaluating the Safety and Efficacy of an ECM Hydrogel for the Treatment of Anorectal Fistulas · ECM Therapeutics, Inc.
- Mar 2027Laser Ablation Versus Conventional Fistulectomy for Uncomplicated Perianal Fistula · PNS Hafeez - Naval Hospital
- Apr 2027Impact of Preoperative Bowel Preparation on Healing Outcomes in FiLaC · Acibadem Kent Hospital
- Apr 2027Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery · Clinique Saint-Vincent
- Apr 2027IFOC Compared With LIFT in High Anal Fistula · Cairo University
Who these studies take
Of the 26 Rectal Fistula studies recruiting now, 18 (69%) set no upper age limit and 7 (27%) stop at 75 or younger. 2 (8%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (4%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (8%) | 2 (8%) |
| 18 | 26 (100%) | 26 (100%) |
| 30 | 25 (96%) | 25 (96%) |
| 40 | 25 (96%) | 25 (96%) |
| 50 | 25 (96%) | 25 (96%) |
| 65 | 24 (92%) | 24 (92%) |
| 75 | 21 (81%) | 21 (81%) |
| 85 | 18 (69%) | 18 (69%) |
Across all 169 studies, recruiting or not: 31% stop at 75 or younger and 16% at 65; 12% take children; 2% are for women only and 2% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Rectal Fistula studies take
Of 57 interventional studies with no phase under Rectal Fistula, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo11–38 · 57 studies | — | 23 mo11–36 · 53 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 169. Browse all 169 → or search them.
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT017931681 country
- Mechanical Bowel Preparation Prior To Sphincter-Sparing Surgery For Complex Anal FistulaeNot yet recruitingNCT07897539Not applicable1 country
- The Use of Electronic Bidets Compared to Water Rinsing After Surgery for Anal Fistula or Haemorrhoidal Disease: a Pilot StudyRecruitingNCT07874711Not applicable1 country
- Seton Re-routing for High Perianal FistulaNot yet recruitingNCT07850440Not applicable
- Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal AbscessNot yet recruitingNCT07704359Phase 41 country
- Patient-Reported Outcomes Following Loose Seton Material Replacement in Complex Anal FistulaNot yet recruitingNCT078186421 country
- Fistura® Procedure for the Treatment of Complex Anal FistulasRecruitingNCT06113068Not applicable1 country
- Impact of Preoperative Bowel Preparation on Healing Outcomes in FiLaCNot yet recruitingNCT07800065
- Open Fistulectomy vs. Laser Closure for Low Perianal FistulaNot yet recruitingNCT07797842Not applicable
- Myriad™ Augmented Soft Tissue Reconstruction RegistryRecruitingNCT052439661 country
- Laser Ablation Versus Conventional Fistulectomy for Uncomplicated Perianal FistulaNot yet recruitingNCT07681531Not applicable1 country
- Female Sexual Function After Surgery for Benign Perianal DiseasesNot yet recruitingNCT07666035
- Study on the Treatment of Anal Fistulas Using Alofisel Versus Fat Autologous Stem CellsRecruitingNCT059742801 country
- BioHealx® Anal Fistula Device Post Market Surveillance StudyRecruitingNCT070217421 country
- TROPIS Versus Coring Out Fistulectomy in High Anal FistulaRecruitingNCT07334678Not applicable1 country
- IFOC Compared With LIFT in High Anal FistulaRecruitingNCT07520500Not applicable1 country
- Effect of Anal Lift Exercise on Rehabilitation After Anal Fistula SurgeryNot yet recruitingNCT07250711Not applicable1 country
- The Impact of Perianal Disease on Patient's Sex LifeRecruitingNCT075198501 country
- Study Evaluating the Safety and Efficacy of an ECM Hydrogel for the Treatment of Anorectal FistulasRecruitingNCT07035925Not applicable1 country
- Impact of Surgical Timing on Anal Fistula OutcomesNot yet recruitingNCT07482241
- Recurrence and Anal Fistula Patient Reported Outcomes TrialRecruitingNCT074774961 country
- FISTULA-RFA Trial: Radiofrequency Ablation for Perianal FistulaNot yet recruitingNCT07452666Not applicable
- Application Effects of Wrist-Ankle Acupuncture in Patients With Different Types of Pain Following Perianal SurgeryRecruitingNCT07340307Not applicable1 country
- Determining the Effect of Education Given to Patients Undergoing Outpatient Anal Fistula SurgeryNot yet recruitingNCT07323160Not applicable
- Effect of Platelet-Rich Plasma Injection on Wound Healing After Fistulotomy for Simple Anal Fistula Randomized Controlled Trial (RCT)Not yet recruitingNCT07248007Phase 1
- A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal FistulasRecruitingNCT05641844Not applicable2 countries
- Fistula-in-ano in Infants and ChildrenRecruitingNCT05666609Not applicable1 country
- Study on the Mechanism of Zuoqing San Promoting Postoperative Wound Healing of Anal Fistula by Inhibiting ROS-dependent NETosisEnrolling by invitationNCT07128953Early Phase 11 country
- Study on Repeat Liposomal Bupivacaine for Post-Surgery Pain in Anal Fistula Patients.RecruitingNCT07081373Not applicable1 country
- Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic SurgeryRecruitingNCT06798155Not applicable1 country
- Machine Learning-Based Risk Stratification for Fistula Formation After Perianal Abscess DrainageNot yet recruitingNCT07019532
- Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's DiseaseRecruitingNCT05039411Phase 11 country
- Cross-cultural Adaptation of the Chinese Version of QoLAF-Q (Quality of Life in Patients With Anal Fistula Questionnaire) :A Multi-center StudyNot yet recruitingNCT06962228
- Efficacy and Safety of Upatinib in the Treatment of Active Anal Fistulas in Crohn's DiseaseRecruitingNCT06902987Phase 11 country
- Effect of Enhanced Recovery After Surgery for Benign Anorectal ConditionsRecruitingNCT06803550Not applicable1 country
- Tissue Therapy of Transsphincteric Anal FistulaRecruitingNCT06303752Phase 1/21 country
- Factors Influencing Wound Healing After Anal Fistula SurgeryNot yet recruitingNCT06592157
- Patient's Quality of Life and Functional Changes After Fistula SurgeryRecruitingNCT065487241 country
- Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal FistulaRecruitingNCT06429241Phase 11 country
- Collagen Paste vs Mucosal Advancement Flap for FIARecruitingNCT06386835Not applicable1 country
- Multicenter Study for Diagnosis and Treatment of Perianal AbscessesRecruitingNCT02306382Not applicable1 country
- Role of Autologous Platelet Rich Plasma(PRP) Injection and Platelet Rich Fibrin Glue(PRFG) Interposition for Treatment of Anal FistulaNot yet recruitingNCT06092398Not applicable
- Could Preoperative Assessment of Physical and Psychological Status Help Predict Pain After Anorectal Surgery?Not yet recruitingNCT060495241 country
- Oral Antibiotics for Anal AbscessRecruitingNCT03643198Not applicable1 country
- BIOlogic Augmented Repair of Complex Anal Fistula Using Acellular Matrix and/or Autologous Platelet-rich PlasmaRecruitingNCT05805449Not applicable1 country
- E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal FistulasActive, not recruitingNCT04190862Phase 11 country
- A Study Of Cryptoglandular Fistula-in-ano And Associated Non-healing Draining Wounds With Kerecis SurgiCloseActive, not recruitingNCT07098715Not applicable1 country
- Evaluating an rhPDGF-BB-enhanced Collagen Plug for Perianal Fistula HealingCompletedNCT06632418Phase 21 country
- Autologous Stem Cells in the Management of Fistulating Perianal Crohn's DiseaseWithdrawnNCT06822686Not applicable
- Comparison Of Surgical Outcomes Between Ligation Of Intersphincteric Fistula Tract And Fistulotomy With Seton In Perianal FistulaCompletedNCT07579715Not applicable1 country