Phenylketonurias: all 187 studies
Page 1 of 2. Open to participants first (38), then studies with results posted, then the rest; newest registration first within each.
- The Impact of Frequency of Home Phenylalanine Measurements on Metabolic Control in a Population of Patients With Classic PhenylketonuriaRecruitingNCT07825883Not applicable
- Market Research of a Slow Release Protein Substitute for the Dietary Management of PKUNot yet recruitingNCT07802366Not applicable
- Impact Of A Phe-Restricted Diet On Gut Health In Children With PKURecruitingNCT07728032
- A Trial to Examine if Repinatrabit is Processed Differently in Adults With Reduced Liver or Kidney Function Compared to Adults With Normal Liver and Kidney FunctionRecruitingNCT07713758Phase 1
- Prevalence and Determinants of Obesity in PKU PatientsEnrolling by invitationNCT07703020
- Eating Disorders in Patients With PhenylketonuriaRecruitingNCT07698743
- A Study of MZE782 in Adults With PKURecruitingNCT07694440Phase 2
- GenSci144 Tablets Phase I Clinical TrialRecruitingNCT07685210Phase 1
- A Clinical Study on the Safety and Tolerability of PL54 Injection in Adult Patients With Phenylketonuria (PKU)RecruitingNCT07672756Phase 1
- PKU Microtablets Case StudiesNot yet recruitingNCT07671859Not applicable
- PheCheck™ Validation StudyRecruitingNCT07551921
- Multiomics Approach in Adult Patients With PhenylketonuriaRecruitingNCT07484945
- Immune Modulation During Palynziq® Treatment in Adults (IMPALA)RecruitingNCT07477691Phase 4
- A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered TogetherRecruitingNCT07446400Phase 1
- The Psychosocial Functioning of Adults With Phenylketonuria.Not yet recruitingNCT07406009
- To Evaluate the Safety and Efficacy of GS1168 Injection in Adult PhenylketonuriaNot yet recruitingNCT07318909Early Phase 1
- A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With PhenylketonuriaRecruitingNCT07241234Phase 1
- A Study of JNT-517 in Participants With Phenylketonuria (PKU)RecruitingNCT06971731Phase 3
- Brain Aging in PhenylketonuriaRecruitingNCT06969209
- GMP Powdered Substitutes in PKU and TYRRecruitingNCT06941532Not applicable
- A Self-test Home-use Blood Phenylalanine Monitoring System Under the Brand Name Egoo Phe System Has Been Developed for Measurement of Phenylalanine (Phe) in Individuals Diagnosed With Phenylketonuria (PKU): The Study Purpose is to Evaluate Accuracy and UsabilityEnrolling by invitationNCT06940193
- Walking Program in Fatty Liver Children With PhenylketonuriaRecruitingNCT06718842Not applicable
- Safety and Efficacy Study of NGGT002 in Adult Patients With PhenylketonuriaRecruitingNCT06687733Phase 1/2
- A Long-Term Study of JNT-517 in Participants With PhenylketonuriaRecruitingNCT06628128Phase 3
- Development of Novel Psychological Assessment Tools and Anxiety Intervention for PhenylketonuriaRecruitingNCT06560736Not applicable
- Effect of Large Neutral Amino Acids in Adults With Classical PhenylketonuriaRecruitingNCT06337864Not applicable
- AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)RecruitingNCT06332807Phase 1/2
- A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)RecruitingNCT06305234
- A Study of Sepiapterin in Participants With Phenylketonuria (PKU)RecruitingNCT06302348Phase 3
- Announcement of Rare Metabolic Diseases in Systematic Newborn Screening: the Phenylketonuria Experience.RecruitingNCT06289348
- Evaluation of Capillary Blood Collection Devices (Mitra® and HemaPEN®)RecruitingNCT05894122
- A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)RecruitingNCT05813678
- Metabolic Control and Patient Well-being in Phenylketonuria: do Guidelines Make a Difference?RecruitingNCT05128149
- Comparison of Atherogenic Risk Factors and Efficacy of Nutritional Treatment Among Adult Phenylketonuria PatientsNot yet recruitingNCT04969809Not applicable
- Phenylalanine-free Diet for Patients With Secondary Hyperphenylalaninemia in ICURecruitingNCT04896281Not applicable
- Nutritional Impacts of Palynziq on Patients With Phenylketonuria (PKU)RecruitingNCT04404530
- Long-Term Follow Up Study of Subjects Previously Administered HMI 102Enrolling by invitationNCT04348708
- Educational, Social Support, and Nutritional Interventions and Their Cumulative Effect on Pregnancy Outcomes and Quality of Life in Teen and Adult Women With PhenylketonuriaRecruitingNCT01659749Not applicable
- Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.TerminatedNCT05827536Not applicableResults posted
- Efficacy and Safety of SYNB1934 in Patients With PKU (SYNPHENY-3)TerminatedNCT05764239Phase 3Results posted
- Evaluation of Phe Fluctuation in PKU Pts Treated With PKU GOLIKE Versus Standard Amino Acid Protein Substitute.CompletedNCT05487378Not applicableResults posted
- Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With PhenylketonuriaActive, not recruitingNCT05270837Phase 3Results posted
- A Study of PTC923 in Participants With PhenylketonuriaCompletedNCT05099640Phase 3Results posted
- Safety and Efficacy of Self Administered Injections of Pegvaliase (>40mg/Day Dose) in Adults With PKUCompletedNCT03694353Phase 3Results posted
- A Study of PTC923 (CNSA-001) in Primary Tetrahydrobiopterin (BH4) Deficient Participants With HyperphenylalaninemiaCompletedNCT03519711Phase 1/2Results posted
- The Effectiveness of Kuvan in Amish PKU PatientsCompletedNCT02677870Phase 4Results posted
- A Phase 3 Substudy to Evaluate Executive Function in Adults With PKU Who Are Participating in the Phase 3 Study, 165-302CompletedNCT02468570Results posted
- Sapropterin on Cognitive Abilities in Young Adults With PhenylketonuriaTerminatedNCT01977820Phase 2Results posted
- The Brain, Neurological Features and Neuropsychological Functioning in Adults With Phenylketonuria: A Pilot StudyCompletedNCT01917344Not applicableResults posted
- Phase 3 Study to Evaluate the Efficacy & Safety of Self-Administered Injections of BMN165 by Adults With PKUCompletedNCT01889862Phase 3Results posted
- An Open-Label Phase 3 Study of BMN 165 for Adults With PKU Not Previously Treated w/ BMN 165CompletedNCT01819727Phase 3Results posted
- A Pilot Study on Diurnal VariationTerminatedNCT01806051Not applicableResults posted
- Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With PhenylketonuriaCompletedNCT01732471Phase 3Results posted
- Effects of Kuvan on Melatonin SecretionCompletedNCT01617070Phase 4Results posted
- A Study to Evaluate Subcutaneously Administered rAvPAL-PEG in Patients With Phenylketonuria for 24 WeeksCompletedNCT01560286Phase 2Results posted
- Bone Mineral Density in Adults With Hyperphenylalaninemia on Kuvan TherapyTerminatedNCT01541397Not applicableResults posted
- Phase 2 Study of Glycomacropeptide Versus Amino Acid Diet for Management of PhenylketonuriaCompletedNCT01428258Not applicableResults posted
- Phenylketonuria, Oxidative Stress, and BH4TerminatedNCT01395394Phase 2Results posted
- Kuvan® in Phenylketonuria Patients Less Than 4 Years OldCompletedNCT01376908Phase 3Results posted
- Safety, Tolerability, and Efficacy Study of rAvPAL-PEG Administered Daily in Subjects With Phenylketonuria (PKU)CompletedNCT01212744Phase 2Results posted
- Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Phenylketonuria (PKU) PatientsCompletedNCT01114737Phase 3Results posted
- Response to Kuvan® in Subjects With Phenylketonuria (PKU) in a 4 Weeks Testing PeriodCompletedNCT01082328Phase 4Results posted
- Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN TherapyCompletedNCT00986973Not applicableResults posted
- Dose-Finding Study to Evaluate the Safety, Efficacy, & Tolerability of Multiple Doses of rAvPAL-PEG in Subjects With PKUCompletedNCT00925054Phase 2Results posted
- Long-Term Extension of Previous rAvPAL-PEG Protocols in Subjects With PKU (PAL-003)CompletedNCT00924703Phase 2Results posted
- Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan ResponseCompletedNCT00841100Phase 2Results posted
- Effect of Kuvan on Neurocognitive Function, Blood Phenylalanine Level, Safety, and Pharmacokinetics in Children With PKUCompletedNCT00838435Phase 3Results posted
- Nutritional and Neurotransmitter Changes in PKU Subjects on BH4CompletedNCT00688844Results posted
- Safety and Efficacy Study of Phenoptin in Subjects With Hyperphenylalaninemia Due to BH4 DeficiencyCompletedNCT00355264Phase 2Results posted
- Study of Phenoptin in Subjects With Phenylketonuria Who Participated in Protocols PKU-004 or PKU-006CompletedNCT00332189Phase 3Results posted
- Study of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted DietCompletedNCT00272792Phase 3Results posted
- Study to Evaluate the Safety and Efficacy of Phenoptin™ in Subjects With Phenylketonuria Who Have Elevated Phenylalanine LevelsCompletedNCT00104247Phase 3Results posted
- Effect of Different Meal Types Given Before Exercise on Plasma Amino Acid Levels and Metabolic Control Parameters in Classical Phenylketonuria Patients Undergoing Aerobic and Resistance ExercisesCompletedNCT07526909Not applicable
- Evaluation of BH4 Responsiveness in Our PKU PatientsActive, not recruitingNCT07255599Phase 1
- Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With PhenylketonuriaActive, not recruitingNCT06901323Phase 4
- Iron Supplements Effect on B-Phe Levels in PKU Patients During 3 Years StudyCompletedNCT06792240Phase 2
- Rapid Drug Desensitization Study in Adults Experiencing Hypersensitivity Reactions to PalynziqCompletedNCT06780332Phase 4
- PKU EASY Microtabs Plus - Acceptability and ToleranceCompletedNCT06694662Not applicable
- A Phase 2 Study of JNT-517 in Adolescent Participants With PhenylketonuriaCompletedNCT06637514Phase 2
- Evaluation of Low Phenylalanine FormulasStatus unknownNCT06332105Not applicable
- The Struggle That Is Phenylketonuria : What Do The Patients and Caregivers Suffer FromCompletedNCT06280261
- A Dose-finding Study to Evaluate mRNA-3210 in Participants With PhenylketonuriaWithdrawnNCT06147856Phase 1/2
- Safety and Efficacy Study of NGGT002 in PKU Adult SubjectsActive, not recruitingNCT06061614Early Phase 1
- PheCheck Feasibility StudyCompletedNCT05998109
- Evaluation of PKU UPCompletedNCT05995717Not applicable
- A Phase 1/Phase 2 Open-label Study to Evaluate the Safety, Tolerability, and Efficacy of a Single Intravenous Administration of SAR444836 in Adult Participants With PhenylketonuriaActive, not recruitingNCT05972629Phase 1/2
- Amino Acid Kinetics of GMP-AA in Healthy Human VolunteersCompletedNCT05971563Not applicable
- Efficacy and Safety of Orally Administered Engineered Probiotics (CBT102-A) for the Treatment of Children With PhenylketonuriaCompletedNCT05948020Early Phase 1
- First-in-Human, Multiple Part Clinical Study of JNT-517 in Healthy Participants and in Participants With PhenylketonuriaCompletedNCT05781399Phase 1/2
- Baby Detect : Genomic Newborn ScreeningCompletedNCT05687474
- The Effect of Nursing Empowerment ProgramCompletedNCT05497050Not applicable
- Preliminary Study of Brain Effects of Palynziq-Related Changes in Phenylalanine in Individuals With PKUCompletedNCT05356377
- Impact of Fruit and Vegetables in PKUCompletedNCT05249218Not applicable
- Study to Evaluate the Effect on Nitrogen Retention of Two Different Posology Schemes of PKU GOLIKE PLUS 3-16 and Free AAs in Patients With PhenylketonuriaTerminatedNCT05229549Not applicable
- Safety and Efficacy of HMI-103 in Participants With Classical PKU Due to PAH DeficiencyTerminatedNCT05222178Phase 1
- Additional Dietary Large Neutral Amino Acids (LNAA) for Improved Symptoms in Adult Classical Phenylktonuria (PKU)Active, not recruitingNCT05174559Not applicable
- A Long-Term Safety Study of PTC923 in Participants With PhenylketonuriaCompletedNCT05166161Phase 3
- Evaluation of PKU Sphere LiquidCompletedNCT05096988Not applicable
- Evaluation of the Express Plus RangeCompletedNCT05051657Not applicable
- Remote Neurocognitive and Psychological Assessment in PKUCompletedNCT04943393