Otosclerosis clinical trials
The registry lists 24 studies for Otosclerosis across more than 10 countries. 5 are recruiting or about to start. 22 of them are mainly about Otosclerosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-25.
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Who runs them
Fondation Ophtalmologique Adolphe de Rothschild (3) · Central Hospital, Nancy, France (2) · Carestream Health, Inc. (1) · İbrahim Emir Yeşil (1) · Hospices Civils de Lyon (1) · University Hospital, Bordeaux (1) · Sohag University (1) · Centre Hospitalier Universitaire de Besancon (1)
What is being tested here
Drugs under test in Otosclerosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 0 | 0 | 1 |
| Remifentanil | 0 | 0 | 1 |
| Acetylcysteine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Dec 2026Cone-beam CT in the Diagnosis and Surgical Treatment of Otosclerosis. · Rigshospitalet, Denmark
Who these studies take
Of the 2 Otosclerosis studies recruiting now, 2 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (50%) | 1 (50%) |
| 18 | 2 (100%) | 2 (100%) |
| 30 | 2 (100%) | 2 (100%) |
| 40 | 2 (100%) | 2 (100%) |
| 50 | 2 (100%) | 2 (100%) |
| 65 | 2 (100%) | 2 (100%) |
| 75 | 2 (100%) | 2 (100%) |
| 85 | 2 (100%) | 2 (100%) |
Across all 24 studies, recruiting or not: 8% stop at 75 or younger and 4% at 65; 25% take children; 0% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 24 of 24. search them.
- Surgical and Audiological Outcomes of Endoscopic Stapes SurgeryNot yet recruitingNCT07304999Not applicable1 country
- Investigating the Relationship Between Temporal Bone CT, Bone Density, and Hearing Loss in Otosclerosis PatientsRecruitingNCT068301871 country
- Ultra-high Resolution CT: the End of Stapes Prosthesis Measurement MisestimationNot yet recruitingNCT063238631 country
- KNOW HOW TO POSITION THE SACCULE AND UTRICULE IN SCANNINGRecruitingNCT061792511 country
- Outcome of Stapes Surgery in Otosclerotic Patients With Tinnitus Using TinnitogramNot yet recruitingNCT06022471
- Audiometric Parameters in Conductive Hearing Loss and Middle Ear DiseaseWithdrawnNCT002224171 country
- Cone-beam CT in the Diagnosis and Surgical Treatment of Otosclerosis.Active, not recruitingNCT05921578Not applicable1 country
- Long-Term Results of Bone Cement in Stapes SurgeryCompletedNCT062210071 country
- Hearing Aid Versus Surgical Rehabilitation as Treatment of Otosclerosis: Pilot StudyCompletedNCT02456272Not applicable1 country
- Dexmedetomidine vs. Remifentanil Conscious Sedation for Stapedotomy/StapedectomyCompletedNCT06283836Not applicable1 country
- The Cost-effectiveness of Stapes Surgery for Otosclerosis Performed Under Local Versus General AnesthesiaCompletedNCT066180531 country
- Interest of Using Deep Learning Algorithm for Otosclerosis Detection on Temporal Bone High Resolution CTActive, not recruitingNCT059872151 country
- Stapes Footplate Thickness Measured With UHR-CTStatus unknownNCT05799404
- Validation of the French Version of the Stapesplasty Outcome Test 25 (SPOT-25)CompletedNCT049088391 country
- Endoscopic Classic Versus Reversal StapedotomyCompletedNCT05554796Not applicable1 country
- Cone Beam vs MDCT for Diagnosis and Pre-operative Evaluation of OtosclerosisTerminatedNCT05214053Not applicable1 country
- Patient Satisfaction After Surgery for Otosclerosis Under Local ou General AnesthesiaCompletedNCT038880791 country
- Wide Frequency Band Test of Hearing in VeteransCompletedNCT020198881 country
- Cone Beam and CT Scan for the Diagnosis of Otosclerosis (TACOS)TerminatedNCT02435446Not applicable1 country
- Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower DoseCompletedNCT01855425Not applicable3 countries
- Quantification of Prosthesis Penetration With Conebeam in OtosclerosisCompletedNCT02901093
- Therapeutic Efficacy of Tiludronic Acid on Inner Ear Involvement in Advanced OtosclerosisTerminatedNCT01617057Phase 31 country
- Clinical Assessment of the External Sound Processor Worn by Patients Implanted With CodacsCompletedNCT02156167Not applicable1 country
- Efficacy of Acetylcysteine in Patients Undergoing Surgery for OtosclerosisCompletedNCT00525551Phase 41 country