Neoplasms, Germ Cell and Embryonal: all 295 studies
Page 1 of 3. Open to participants first (51), then studies with results posted, then the rest; newest registration first within each.
- Phase 1/2 Study Of PARP Inhibition With Olaparib To Enhance The Efficacy Of High-Dose Chemotherapy In Refractory And Relapsed Germ Cell TumorsNot yet recruitingNCT07850973Phase 1/2
- Paclitaxel-Bleomycin/Etoposide/Cisplatin vs Bleomycin/Etoposide/Cisplatin in Poor-prognosis Non-seminomatous Germ Cell Tumors (NSGCT) and Unfavorable Tumor Marker Decline: Randomized Phase II TrialRecruitingNCT07847190Phase 2
- Sentinel Node Identification Using Gamma and Near-Infrared Imaging in TesticulAr MaLignanciesRecruitingNCT07777887
- A Simplified Regimen to Prevent Nausea and Vomiting Using Netupitant/Palonosetron in Germ Cell Cancer Patients Receiving ChemotherapyNot yet recruitingNCT07662200Early Phase 1
- Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid TumorsRecruitingNCT07628634Early Phase 1
- Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin.RecruitingNCT07188441Phase 2
- A Study of ZW251 in Participants With Advanced Solid TumorsRecruitingNCT07164313Phase 1
- Dornase Alfa and Cisplatin in Refractory Germ Cell Cancer.RecruitingNCT07121322Phase 2
- Tumor-Lymph Node MappingNot yet recruitingNCT07054944
- A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.RecruitingNCT07017816Early Phase 1
- Maintenance Zanzalintinib With Etoposide After HDCT in GCTRecruitingNCT06937866Phase 1/2
- A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving ChemotherapyRecruitingNCT06866964Phase 2
- Patient Reported Experiences With Sparing External Oblique Fascia Vs Standard Inguinal OrchiectomyRecruitingNCT06828185Not applicable
- High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell TumorsRecruitingNCT06418789Phase 2
- Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid TumoursNot yet recruitingNCT06363201Not applicable
- SerUm and Plasma MicroRNAs in Malignant Ovarian gERm Cell TumoursNot yet recruitingNCT06329323
- Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid TumorsRecruitingNCT06276491Phase 1
- Sentinel Lymph Node Biopsy in Stage AI-IIA Germ Cell TumorsRecruitingNCT06133699Not applicable
- Robot-assisted ICG-guided Sentinel Node Biopsy in Testicular CancerRecruitingNCT06133543Not applicable
- Morbidity, Long-term Side Effects and Quality of Life in Germ-cell Tumor Long Survivors Treated with High-dose Chemotherapy and Autologous Stem Cell TransplantRecruitingNCT05889585Not applicable
- Thromboprophylaxis in Good and Intermediate Prognosis Advanced Germ Cell TumorsRecruitingNCT05874063Phase 3
- Rare Embryonal Tumors of the Central Nervous System: International RegistryRecruitingNCT05711992
- Validation of a Treatment Algorithm for Poor-Risk NSGCTnon Seminomatous Germ-cell TumorsRecruitingNCT05705687Not applicable
- Follow-up After Surgery for Testicular CancerRecruitingNCT05670938
- A Study of HX008 Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the LiverNot yet recruitingNCT05647954Phase 3
- Molecular Epidemiology of Pediatric Germ Cell TumorsRecruitingNCT05564026
- Multidisciplinary Approach to FatigueRecruitingNCT05502224Not applicable
- Paclitaxel/Ifosfamide/Cisplatin Chemotherapy for High Risk Pediatric Germ Cell TumorRecruitingNCT05455918Phase 2
- GD2-CAR T Cells for Pediatric Brain TumoursRecruitingNCT05298995Phase 1
- Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric PatientsRecruitingNCT05293197Phase 1
- Lutathera for Treatment of Recurrent or Progressive High-Grade CNS TumorsRecruitingNCT05278208Phase 1/2
- Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO ClassificationRecruitingNCT05259605
- Prospective Study on Quality of Life in Patients With Intracranial Germ Cell TumorsRecruitingNCT05124964
- The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell TumorsRecruitingNCT05124951Phase 2
- Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological MalignancesRecruitingNCT05092451Phase 1/2
- Spanish Series of Patients Treated With the Radionuclide Lutetium177RecruitingNCT04949282
- MicroRNA as Markers in Testicular CancerRecruitingNCT04914026
- B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)RecruitingNCT04897321Phase 1
- Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCTRecruitingNCT04804007Phase 2
- Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS MalignanciesRecruitingNCT04308330Phase 1
- Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System TumorsRecruitingNCT04185038Phase 1
- C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)RecruitingNCT04099797Phase 1
- HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 1
- Sentinel Lymph Node Procedure in Testicular Germ Cell TumourNot yet recruitingNCT03448822
- A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsRecruitingNCT03093116Phase 1/2
- Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell TumorsRecruitingNCT03067181Phase 3
- Embryonal Tumors of Infancy & Childhood: South Egypt Cancer Institute ExperienceRecruitingNCT02665676
- Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell TumoursRecruitingNCT02582697Phase 3
- TC or BEP in Treating Patients With Malignant Ovarian Germ Cell TumorsRecruitingNCT02429687Phase 3
- Germ Cell Tumor and Testicular Tumor DNA RegistryRecruitingNCT02099734
- The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative RegimenRecruitingNCT01890486
- Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas SystemCompletedNCT04743310Phase 2Results posted
- Immunohistochemical Evaluation of Protein P16 Expression in Ovarian Germ Cell Tumors.CompletedNCT04283773Results posted
- A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)TerminatedNCT04222972Phase 3Results posted
- Symptom Management for YA Cancer SurvivorsCompletedNCT04035447Not applicableResults posted
- A Study to Assess the Safety and Efficacy of ASP1650, a Monoclonal Antibody Targeting Claudin 6 (CLDN6), in Male Subjects With Incurable Platinum Refractory Germ Cell TumorsCompletedNCT03760081Phase 2Results posted
- Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03233204Phase 2Results posted
- Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain TumorsCompletedNCT03194906Phase 2Results posted
- Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid TumorsCompletedNCT03037385Phase 1/2Results posted
- Study of Brentuximab Vedotin And Bevacizumab In Refractory CD-30 Positive Germ Cell TumorsTerminatedNCT02988843Phase 2Results posted
- Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary MetastasesTerminatedNCT02859415Phase 1/2Results posted
- Brentuximab Vedotin in Relapsed/Refractory Germ Cell TumorsTerminatedNCT02689219Phase 2Results posted
- Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell TumorsTerminatedNCT02499952Phase 2Results posted
- Molecular-Guided Therapy for Childhood CancerCompletedNCT02162732Not applicableResults posted
- Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid TumorsCompletedNCT02095132Phase 1/2Results posted
- A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell TumorsTerminatedNCT01962896Phase 2Results posted
- Palifosfamide in Treating Patients With Recurrent Germ Cell TumorsTerminatedNCT01808534Phase 2Results posted
- Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Germ Cell TumorsCompletedNCT01736917Phase 2Results posted
- Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron OverloadTerminatedNCT01159067Phase 2Results posted
- Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological MalignanciesCompletedNCT01079832Phase 2Results posted
- ARQ 197 for Participants With Relapsed or Refractory Germ Cell TumorsTerminatedNCT01055067Phase 2Results posted
- Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With CancerCompletedNCT01037790Phase 2Results posted
- Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell TumorsCompletedNCT00957905Phase 2Results posted
- High-dose Chemotherapy for Poor-Prognosis Relapsed Germ-Cell TumorsCompletedNCT00936936Phase 2Results posted
- Sunitinib Malate in Refractory Germ Cell TumorsTerminatedNCT00912912Phase 2Results posted
- Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell TransplantCompletedNCT00795769Phase 2Results posted
- Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid TumorsTerminatedNCT00788125Phase 1/2Results posted
- Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyCompletedNCT00716976Phase 3Results posted
- Aprepitant + a 5HT3 + Dexamethasone in Patients With Germ Cell TumorsCompletedNCT00572572Phase 3Results posted
- Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell TumorsCompletedNCT00470366Phase 2Results posted
- Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell TumorsCompletedNCT00467051Phase 2Results posted
- Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to TreatmentCompletedNCT00453310Phase 2Results posted
- Autologous Peripheral Blood Stem Cell Transplant for Germ Cell TumorsCompletedNCT00432094Phase 2Results posted
- Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to CisplatinCompletedNCT00423852Phase 1/2Results posted
- Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell TransplantCompletedNCT00408681Not applicableResults posted
- Study of Oxaliplatin Plus Bevacizumab in Germ Cell Tumor PatientsCompletedNCT00393861Phase 2Results posted
- Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell TransplantCompletedNCT00293384Not applicableResults posted
- Study of Gemcitabine, Oxaliplatin, and Paclitaxel in Patients With Refractory Germ Cell CarcinomaCompletedNCT00183820Phase 2Results posted
- Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell TumorsCompletedNCT00104676Phase 3Results posted
- Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell TumorsCompletedNCT00053352Phase 3Results posted
- Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell TumorsCompletedNCT00047320Phase 2Results posted
- Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid TumorsCompletedNCT00024258Phase 2Results posted
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell CancerCompletedNCT00002931Phase 2Results posted
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell TumorsCompletedNCT00002558Phase 1/2Results posted
- A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From SpermWithdrawnNCT06940804Phase 2
- Thalidomide Combined With Chemotherapy in the Treatment of Relapsed or Refractory Yolk Sac TumorCompletedNCT06470464Phase 2
- Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in ChildrenCompletedNCT06341998Phase 2/3
- GAMEC-II, Risk-adapted Protocol for Relapsed Germ Cell Tumours (GCT)CompletedNCT06309732Phase 2
- YASU Research Registry: For Young Adults With CancerTerminatedNCT06275854
- Survival and Reproductive Outcomes of Malignant Ovarian Germ Cell TumorsCompletedNCT05905289