Myeloproliferative Disorders: all 640 studies
Page 1 of 7. Open to participants first (111), then studies with results posted, then the rest; newest registration first within each.
- Phase 2 Study of Oral Epetraborole in Adults With Polycythemia VeraNot yet recruitingNCT07891533Phase 2
- A Study to Evaluate DMR-001 in Participants With CALR-mutant Myeloproliferative NeoplasmsRecruitingNCT07849231Phase 1
- Pulmonary Hypertension and RV Dysfunction in Myeloproliferative NeoplasmsNot yet recruitingNCT07834918
- Study of Pregnancy in Patients With Myeloproliferative NeoplasmsNot yet recruitingNCT07832513
- Caris Chromoseq Data CollectionRecruitingNCT07680868
- Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative NeoplasmsNot yet recruitingNCT07679334Phase 1
- Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in MPN PatientsNot yet recruitingNCT07648433
- Automated Total Marrow and Lymphoid Irradiation for Allogeneic Hematopoietic Cell TransplantNot yet recruitingNCT07634536Phase 2
- Selinexor Monotherapy for Cytoreduction in BCR::ABL1-Negative Myeloproliferative NeoplasmsNot yet recruitingNCT07626021Phase 2
- Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With ThrombocytosisRecruitingNCT07612280Phase 1/2
- Identification of MPN-specific Antigens and Anti-MPN TCRs in Myeloproliferative NeoplasmRecruitingNCT07590986
- A Pragmatic Clinical Trial to Prevent Relapse for Myeloid Malignancies With Measurable Disease Prior to Allogeneic TransplantNot yet recruitingNCT07572929Phase 2
- Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic MalignanciesRecruitingNCT07565220Phase 1
- Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX)Not yet recruitingNCT07528417Phase 2
- ENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic Myeloid LeukemiaNot yet recruitingNCT07518940Not applicable
- A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative NeoplasmsRecruitingNCT07469891Phase 1
- Ropeginterferon Alfa-2b for the Treatment of Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes and Chronic Myelomonocytic LeukemiaNot yet recruitingNCT07468916Phase 2
- Chemogenomic Profiling in Hematological Malignancies (HEM-Profiling 2021)RecruitingNCT07445984Not applicable
- Feasibility of a Multi-omics Platform for Hematological MalignanciesRecruitingNCT07445438Not applicable
- Study of INCA036978 in Participants With Myeloproliferative NeoplasmsRecruitingNCT07441694Phase 1
- A New Diagnostic Algorithm to Non-invasively Track Fibrotic Changes in Myeloproliferative Neoplasms Based on C-C Chemokine Receptor 2 Detection. From Flow Cytometry to the Development of Targeted Positron Emission Tomography Molecular Imaging. Pre-clinical Studies and First In-human Proof of ConceptRecruitingNCT07419178Not applicable
- INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP)RecruitingNCT07403630Not applicable
- Exercise Training in Patients With Myeloproliferative NeoplasmsRecruitingNCT07384039Not applicable
- Therapeutic RSK1 Targeting in Myeloid MalignanciesRecruitingNCT07379125Phase 1
- MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)RecruitingNCT07362225
- WELL-MPN: A Digital Lifestyle App for Patients With MPNsNot yet recruitingNCT07349134Not applicable
- Ropeginterferon for High Risk JAK2 Clonal HematopoiesisRecruitingNCT07249840Phase 1
- Unveiling the Germline Predisposition to Myeloproliferative NeoplasmsRecruitingNCT07204392
- Prognostic Value of NETosis Markers for Thrombosis During Myeloproliferative Neoplasms (AVATARE)RecruitingNCT07119970Not applicable
- Hematological Disorders in EHPVO PatientsNot yet recruitingNCT07108023
- A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell TransplantRecruitingNCT07020533Phase 1
- A Study to Evaluate INCA035784 in Participants With Myeloproliferative NeoplasmsRecruitingNCT07008118Phase 1
- Prevalence Of Germline Gene Mutations In Patients With Myeloproliferative Neoplasms With Family HistoryNot yet recruitingNCT06923670Not applicable
- Anti-NKG2A Monoclonal Antibody for AML or MDS Patients Undergoing Haploidentical TransplantationRecruitingNCT06892223Phase 2
- A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell TransplantationRecruitingNCT06859424Phase 2
- Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity ConditioningRecruitingNCT06815003Phase 2
- Clinical Significance of Leukocyte Cell Population Data in Patients with Myeloproliferative Neoplasms (MPNs)Not yet recruitingNCT06753279
- Ropeginterferon Alfa-2b in Patients With Polycythemia Vera (PV) Without Symptomatic SplenomegalyRecruitingNCT06743035
- Long-term Efficacy of Once Daily Versus Twice Daily Aspirin in High-risk MPN Patients with Aspirin ResistanceRecruitingNCT06740916Phase 3
- CAR-NK Cells Production and Expansion From Patients With Lympho or Myeloproliferative Disorders and From Healthy DonorsRecruitingNCT06727383Not applicable
- Children, Adolescents and Young Adults with Myeloproliferative Neoplasia: Study of Clinico-biological Characteristics and Complications (VYP)RecruitingNCT06715267
- A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)RecruitingNCT06661915Phase 2
- Prevalence and Risk Factors of Pulmonary Hypertension in Patients with Myeloproliferative Neoplasms in Assiut University Hospital.Not yet recruitingNCT06647706
- Cardiovascular Manifestations in Ph-negative MPNNot yet recruitingNCT06615414
- Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid LeukemiaRecruitingNCT06599762Phase 2
- Sorafenib Relapase Prophylaxis After HCT With PTBCy RegimenRecruitingNCT06532084Phase 2
- Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic LeukemiaRecruitingNCT06523556Phase 1/2
- Evaluation of the Pathobiology of CALR-mutated MPN CellsRecruitingNCT06480591
- BeFluBu vs FluBuRux Conditioning in Haploidentical HCTRecruitingNCT06477549Phase 2
- Exploring the Impact of Monocytes in Myeloproliferative Neoplasia (EMYNEM)RecruitingNCT06462664
- Brain MRF in Children, Adolescents and Young Adults With Acute LeukemiaRecruitingNCT06421155Not applicable
- Functional and Phenotypic Characterization of Monocytes in Myeloproliferative SyndromesRecruitingNCT06361641Not applicable
- A Prospective Patient Reported Outcomes and Wearables Study in Myeloproliferative NeoplasmsNot yet recruitingNCT06334913
- Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell TransplantRecruitingNCT06315309Phase 2
- Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative NeoplasmsRecruitingNCT06303193Phase 1/2
- Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene MutationRecruitingNCT06291987Phase 1
- Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell TransplantRecruitingNCT06265584Phase 2
- Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 InhibitionRecruitingNCT06218628Phase 1
- A New Blood Score for Myelofibrosis StagingNot yet recruitingNCT06177366
- Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell TransplantationRecruitingNCT06138587Phase 1
- Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a SolutionRecruitingNCT06131801
- CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell TransplantRecruitingNCT06059391Phase 2
- A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative NeoplasmsRecruitingNCT06034002Phase 1
- MultiOmic characteriZation of Acute Myeloid Leukemia Evolving From myelopRoliferative Neoplasm to Identify New Targeted Therapeutic StrategiesNot yet recruitingNCT06022341Not applicable
- Impact of Epigenetic Age on Clinic-biological Presentation and Prognosis in Myeloproliferative Neoplasms Epigenetic Age in Myeloproliferative Neoplasms (EpiC)RecruitingNCT06022328
- Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic DiseasesRecruitingNCT06013423Phase 2
- Carotid Plaque Burden in Patients With Philadelphia Negative Myeloproliferative NeoplasmsRecruitingNCT05993052
- Clonal Hematopoiesis of Immunological SignificanceNot yet recruitingNCT05969821
- Asian Myeloproliferative Neoplasm (MPN) RegistryRecruitingNCT05882773
- Mechanism of Action of Interferon in the Treatment of Myeloproliferative NeoplasmsRecruitingNCT05850273
- I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm PatientsRecruitingNCT05842603Not applicable
- Determination of the Clonality Profile in Myeloproliferative Neoplasms and Association With the Thrombotic Complications (CLOJAK)RecruitingNCT05839717
- Allo HSCT Using RIC and PTCy for Hematological DiseasesRecruitingNCT05805605Phase 2
- A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDSRecruitingNCT05788679Phase 2
- Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNsRecruitingNCT05782985
- Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and CareRecruitingNCT05745285Not applicable
- Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic AbnormalitiesRecruitingNCT05714592Not applicable
- MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)RecruitingNCT05564390Phase 2
- Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)RecruitingNCT05554406Phase 2
- Evaluation of Inflammatory Markers in ph Negative Myeloproliferative Neoplasms: Impact on Outcome and Response to Therapy. Multicenter Retro-prospective Observational Study. The INFLA-ME (INFLAmmation in Myeloproliferative Disease) Study.RecruitingNCT05553873
- Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap NeoplasmsRecruitingNCT05549661Phase 1
- Olverembatinib for FGFR1-rearranged NeoplasmsRecruitingNCT05521204Phase 2
- Identification of Factors Associated With Treatment Response in Patients With Polycythemia Vera, Essential Thrombocythemia, and Pre-myelofibrosis.RecruitingNCT05440838
- Leading in MPNs Beyond Ruxolitinib in Combo With T-RegsRecruitingNCT05423691Phase 1
- The Patient Cohort of the National Center for Precision Medicine in LeukemiaRecruitingNCT05326919
- Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and AnemiaRecruitingNCT05320198Phase 1/2
- An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative NeoplasmsRecruitingNCT05123365Phase 1/2
- Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative NeoplasmsRecruitingNCT05074355Phase 2
- (Apex) Bezuclastinib in Patients With Advanced Systemic MastocytosisRecruitingNCT04996875Phase 2
- Interest of CALR Allele Burden in Diagnosis and Follow-up of Patients With CALR Mutated Myeloproliferative Syndromes (CALRSUIVI)RecruitingNCT04942080Not applicable
- Improving Cognitive Function in Older Adults Undergoing Stem Cell TransplantRecruitingNCT04898790Not applicable
- Asciminib Roll-over StudyRecruitingNCT04877522Phase 4
- Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant DisordersRecruitingNCT04644016Phase 2
- CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic SyndromeRecruitingNCT04493164Phase 2
- Sequential and Personalized PK-guided Busulfan Administration in the Frame of the Conditiong Regimen for Allo-HSCT in Patients With Malignant Hemopathies Ineligible for the Standard Myeloablative ConditioningNot yet recruitingNCT04451200Phase 2
- Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative NeoplasmsRecruitingNCT04282187Phase 2
- A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical TrialsRecruitingNCT04064060Phase 3
- A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell TransplantationRecruitingNCT04024761Phase 1
- Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)RecruitingNCT03970096Phase 2
- Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity ConditioningRecruitingNCT03852407Phase 2