Muscular Atrophy, Spinal: all 295 studies
Page 3 of 3. Open to participants first (78), then studies with results posted, then the rest; newest registration first within each.
- Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV PatientsActive, not recruitingNCT04690998Not applicable
- Ultrasound-assisted vs Landmark Based Intrathecal Administration of NusinersenCompletedNCT04674618Not applicable
- Responsiveness and Validation Study of MFM-20 in SMA Patients Treated With NusinersenStatus unknownNCT04644393
- Responsiveness and Validation Study of MFM-32 in SMA Patients Treated With NusinersenCompletedNCT04602195
- Adults With SMA Treated With NusinersenCompletedNCT04591678
- Metabolomics of Children With SMACompletedNCT04587492
- Study of the Functional Effects of Nusinersen in 5q-spinal Muscular Amyotrophy Adults (SMA Type 2 or 3 Forms)CompletedNCT04576494Not applicable
- A Study to Learn About the Effect of Nusinersen (BIIB058) Given as Injections to Children With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec (RESPOND)CompletedNCT04488133Phase 4
- Non-Interventional, Postmarketing Surveillance Study of Nusinersen Sodium InjectionCompletedNCT04419233
- Characterization of the Clinical-epidemiological Profile of Patients With SMA5q Types II and III: Observational StudyCompletedNCT04404764
- Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile SensorCompletedNCT04335942Not applicable
- A Study of the Safety of Nusinersen (Spinraza®) and Its Effects on Motor Function in Koreans Living With SMA Treated During Their Usual Medical CareActive, not recruitingNCT04317794
- Evaluation of Therapeutic Response in Spinal Muscular Atrophy Using Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI)Status unknownNCT04262570Not applicable
- An Expanded Access Program for Risdiplam in Participants With Spinal Muscular Atrophy (SMA)Approved for marketingNCT04256265
- The Burden of Primary Caregivers of Spinal Muscular Atrophy Patients and Their NeedsCompletedNCT04228718
- Muscle Structure, Function and Gait in dHMNCompletedNCT04193228
- Wearable Technology to Assess Gait Function in SMA and DMDCompletedNCT04193085
- Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA®Active, not recruitingNCT04159987Not applicable
- Motor Unit Number Estimation (MUNE) in Adults With Spinal Muscular Atrophy (SMA)CompletedNCT04139343
- New Imaging Biomarkers for Muscular Diseases - Multispectral Optoacoustic Imaging in Spinal Muscular AtrophyCompletedNCT04115475Not applicable
- Pulmonary Function Test Changes and Respiratory Muscle Strength Trends in Spinal Muscular Atrophy Patients Receiving Nusinersen TreatmentsWithdrawnNCT04050852Early Phase 1
- Fat and Glucose Metabolism in Fed and Fasted State in Patients With Low Skeletal Muscle MassCompletedNCT03970135Not applicable
- AveXis Managed Access Program Cohort for Access to AVXS-101Approved for marketingNCT03955679
- TRIAL READY (Clinical Trial Readiness)Active, not recruitingNCT03912987
- Effect of Nusinersen on Adults With Spinal Muscular AtrophyCompletedNCT03878030
- Reliability and Validity of the ACTIVE-mini for Quantifying Movement in Infants With Spinal Muscular AtrophyCompletedNCT03808233
- Spinraza in Adult Spinal Muscular AtrophyActive, not recruitingNCT03709784
- Study of ALS Reversals 4: LifeTime ExposuresCompletedNCT03706391
- Feasibility of Virtual Reality in Children With Neuromuscular Disease, Effectiveness of Virtual Reality and BiofeedbackCompletedNCT03689660Not applicable
- Early Check: Expanded Screening in NewbornsActive, not recruitingNCT03655223
- Sun May Arise on SMA : Newborn Screening of Spinal Muscular Atrophy in BelgiumCompletedNCT03554343
- Improving Standards of Care and Translational Research in Spinal Muscular Atrophy (SMA)Status unknownNCT03520179
- Study of ALS Reversals 2: Genetic AnalysesCompletedNCT03464903
- Trial Evaluating the Interest of Noninvasive Ventilation in NAVA Mode in Respiratory Decompensations Children With Infantile Spinal Muscular Atrophy Type IICompletedNCT03395795Not applicable
- European Registry of Patients With Infantile-onset Spinal Muscular AtrophyCompletedNCT03339830
- Natural History of Types 2 and 3 SMA in TaiwanStatus unknownNCT03300869
- Development of a Space Exploration Assessment for Children With Spinal Muscular AtrophyCompletedNCT03223051Not applicable
- A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.TerminatedNCT03196375Phase 2
- Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron DiseaseStatus unknownNCT03067857Phase 1/2
- SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4CompletedNCT02941328Phase 2
- Oxidative Capacity and Exercise Tolerance in Ambulatory SMACompletedNCT02895789
- Effect of Low-Dose Celecoxib on SMN2 in Patients With Spinal Muscular AtrophyTerminatedNCT02876094Phase 2
- Expanded Access Program (EAP) for Nusinersen in Participants With Infantile-onset (Consistent With Type 1) Spinal Muscular Atrophy (SMA)No longer availableNCT02865109
- Allogeneic Adipose Derived Stem Cells for Werdnig Hoffman PatientsStatus unknownNCT02855112Phase 1/2
- A Patient Centric Motor Neuron Disease Activities of Daily Living ScaleCompletedNCT02852278
- Prospective Evaluation of Infants With Spinal Muscular Atrophy:Status unknownNCT02831296
- A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) Given by Mouth in Healthy VolunteersCompletedNCT02633709Phase 1
- Answer ALS: Individualized Initiative for ALS DiscoveryCompletedNCT02574390
- Identification of a Biomarker Associated With Cis-duplication of the SMN1 GeneTerminatedNCT02550691Not applicable
- Genetics of Pediatric-Onset Motor Neuron and Neuromuscular DiseasesCompletedNCT02532244
- Natural History of Spinal Muscular Atrophy Type 1 in TaiwanCompletedNCT02466529
- Effects of Standing on Non-Ambulatory Children With Neuromuscular ConditionsCompletedNCT02428673Not applicable
- Prospective Study of the Natural History of Patients With Type 2 and 3 Spinal Muscular AtrophyCompletedNCT02391831Not applicable
- Effects of Standing on Non-Ambulatory Children With Spinal Muscular AtrophyCompletedNCT02341053Not applicable
- Phenotype, Genotype & Biomarkers in ALS and Related DisordersActive, not recruitingNCT02327845
- A Study of RO6885247 in Adult and Pediatric Patients With Spinal Muscular Atrophy (MOONFISH)TerminatedNCT02240355Phase 1
- Study of Feasibility to Reliably Measure Functional Abilities' Changes in Nonambulant Neuromuscular Patients Without Trial Site VisitingWithdrawnNCT02235090Not applicable
- Safety and Efficacy Study of Pyridostigmine on Patients With Spinal Muscular Atrophy Type 3CompletedNCT02227823Phase 2
- Reciprocating Gait Orthoses for Paraplegia PatientsStatus unknownNCT02227407Not applicable
- National Registry for Egyptian Pediatric Neuromuscular DiseasesStatus unknownNCT02124616
- Newborn Screening for Spinal Muscular AtrophyCompletedNCT02123186
- Pilot Study of an Innovative Physiotherapy in Patients With Infantile Spinal Muscular Atrophy (SMA)CompletedNCT02061189Not applicable
- An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246)CompletedNCT02052791Phase 1
- Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.CompletedNCT02044029
- Aerobic Training in Patients With Spinal Muscular Atrophy Type IIICompletedNCT02003937Not applicable
- Optimum Insufflation Capacity in NMDCompletedNCT01981915Not applicable
- At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic ConditionsCompletedNCT01931644
- A Study to Collect Blood Samples From Patients With Spinal Muscular Atrophy for Biomarker AnalysisCompletedNCT01910168
- Palliative Care in Spinal Muscular Atrophy (SMA) 1CompletedNCT01862042Not applicable
- An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)CompletedNCT01780246Phase 1
- Mechanisms of Cell Death in Spinal Muscular AtrophyCompletedNCT01754441
- Valproate and Levocarnitine in Children With Spinal Muscular AtrophyStatus unknownNCT01671384Phase 3
- Multi-disease Carrier Screening Test ValidationWithdrawnNCT01663584
- Clinical Assessment of Spinal Muscular Atrophy Type II and III (SMA Europe)CompletedNCT01611610Not applicable
- Infants With Spinal Muscular Atrophy Type ITerminatedNCT01547871
- Spinal Muscular Atrophy and Cardiac Autonomic FunctionCompletedNCT01522079Not applicable
- An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)CompletedNCT01494701Phase 1
- Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.CompletedNCT01302600Phase 2
- Clinical Trial of Exercise in Patients With Spinal Muscular Atrophy (SMA)CompletedNCT01166022Not applicable
- SMN Copy Number Distribution in Mali, West AfricaCompletedNCT01059240
- Evaluation of the Muscle Strength and Motor Ability in Children With Spinal Muscle Atrophy(SMA) Treated With Valproic AcidCompletedNCT01033331
- Effects of Power Mobility on Young Children With Severe Motor ImpairmentsCompletedNCT01028833Phase 2
- Motor Development and Orthoses in Spinal Muscular Atrophy (SMA)CompletedNCT00961103
- A Pilot Study of Biomarkers for Spinal Muscular AtrophyCompletedNCT00756821
- Pilot Study of Growth Hormon to Treat SMA Typ II and IIICompletedNCT00533221Phase 2
- A Trial of Hydroxyurea in Spinal Muscular AtrophyCompletedNCT00485511Phase 2/3
- Valproic Acid in Ambulant Adults With Spinal Muscular AtrophyCompletedNCT00481013Phase 2
- International SMA Patient RegistryCompletedNCT00466349
- Clinical Study of Spinal Muscular AtrophyCompletedNCT00443066
- Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular AtrophyCompletedNCT00374075Phase 1
- Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron DiseaseCompletedNCT00324454Phase 2
- Quantitative Analysis of SMN1 and SMN2 Gene Based on DHPLC SystemStatus unknownNCT00155168
- Establishing Novel Detection Techniques for Various Genetic-Related Diseases by Applying DHPLC Platform.Status unknownNCT00154960
- Measuring Levels of SMN in Blood Samples of SMA PatientsCompletedNCT00061607
- Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron DiseaseCompletedNCT00004771Phase 2