Mesothelioma: all 475 studies

Page 2 of 5. Open to participants first (75), then studies with results posted, then the rest; newest registration first within each.

• Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM)TerminatedNCT03175172Phase 2Results posted
• Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic MalignanciesCompletedNCT03126110Phase 1/2Results posted
• A Phase 2 Study of Durvalumab in Combination With Tremelimumab in Malignant Pleural MesotheliomaTerminatedNCT03075527Phase 2Results posted
• CAR T Cells in Mesothelin Expressing CancersCompletedNCT03054298Phase 1Results posted
• Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid TumorsCompletedNCT02903914Phase 1Results posted
• Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma PatientsCompletedNCT02899299Phase 3Results posted
• Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable MesotheliomaCompletedNCT02899195Phase 2Results posted
• Study of the EZH2 Inhibitor Tazemetostat in Malignant MesotheliomaCompletedNCT02860286Phase 2Results posted
• Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary MetastasesTerminatedNCT02859415Phase 1/2Results posted
• Mesothelin-Targeted Immunotoxin LMB-100 in People With Malignant MesotheliomaCompletedNCT02798536Phase 1Results posted
• Pembrolizumab in Patients With Advanced Malignant Pleural MesotheliomaCompletedNCT02784171Phase 2/3Results posted
• Ph 2/3 Study in Subjects With MPM to Assess ADI-PEG 20 With Pemetrexed and CisplatinCompletedNCT02709512Phase 2/3Results posted
• Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural MesotheliomaTerminatedNCT02672033Not applicableResults posted
• Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural MesotheliomaCompletedNCT02611037Phase 2Results posted
• Phase II Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma (MPM)CompletedNCT02610140Phase 2Results posted
• 18F-FSPG PET/CT for Cancer Patients on TherapyCompletedNCT02599194Phase 2Results posted
• MEDI4736 Or MEDI4736 + Tremelimumab In Surgically Resectable Malignant Pleural MesotheliomaCompletedNCT02592551Phase 2Results posted
• Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is RecurrentCompletedNCT02568449Phase 2Results posted
• Genetically Modified T Cells in Treating Patients With Stage III-IV Non-small Cell Lung Cancer or MesotheliomaTerminatedNCT02408016Phase 1/2Results posted
• Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM)TerminatedNCT02357147Phase 2Results posted
• Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family CaregiversCompletedNCT02349412Phase 3Results posted
• A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural MesotheliomaCompletedNCT02347917Phase 1/2Results posted
• Phase II Trial of Alisertib (MLN8237) in Salvage Malignant MesotheliomaCompletedNCT02293005Phase 2Results posted
• αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface MalignanciesCompletedNCT02151448Phase 1/2Results posted
• Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without ChemotherapyTerminatedNCT02062632Phase 2Results posted
• HIPEC for Peritoneal CarcinomatosisCompletedNCT02040142Phase 2Results posted
• Window of Opportunity Study of VS-6063 (Defactinib) in Surgical Resectable Malignant Pleural Mesothelioma ParticipantsTerminatedNCT02004028Phase 2Results posted
• Nintedanib (BIBF 1120) in MesotheliomaTerminatedNCT01907100Phase 2/3Results posted
• Tivantinib in Treating Patients With Previously Treated Malignant MesotheliomaTerminatedNCT01861301Phase 2Results posted
• Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural MesotheliomaCompletedNCT01675765Phase 1Results posted
• Mithramycin for Lung, Esophagus, and Other Chest CancersTerminatedNCT01624090Phase 2Results posted
• Erlotinib Hydrochloride in Treating Patients With Malignant Peritoneal MesotheliomaCompletedNCT01592383Phase 2Results posted
• CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic CancerTerminatedNCT01583686Phase 1/2Results posted
• Early Palliative Care in Advanced Lung and Gastrointestinal MalignanciesCompletedNCT01401907Not applicableResults posted
• SS1P and Pentostatin Plus Cyclophosphamide for MesotheliomaCompletedNCT01362790Phase 1/2Results posted
• Galinpepimut-S (WT-1 Analog Peptide) Vaccine in Malignant Pleural Mesothelioma After Combined Modality TherapyCompletedNCT01265433Phase 2Results posted
• Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)CompletedNCT01204203Phase 2Results posted
• Phase II Study of IMC-A12 in Patients With Mesothelioma Who Have Been Previously Treated With ChemotherapyCompletedNCT01160458Phase 2Results posted
• Anti-TGF Monoclonal Antibody (GC1008) in Relapsed Malignant Pleural MesotheliomaCompletedNCT01112293Phase 2Results posted
• NGR015: Study in Second Line for Patient With Advanced Malignant Pleural Mesothelioma Pretreated With PemetrexedCompletedNCT01098266Phase 3Results posted
• Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line ChemotherapyCompletedNCT01085630Phase 2Results posted
• Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict SensitivityCompletedNCT01024946Phase 2Results posted
• Trimodal Lung-Sparing Treatment of Pleural MesotheliomaTerminatedNCT00859495Phase 2Results posted
• Eloxatin® Plus Gemcitabine Chemotherapy for MesotheliomaCompletedNCT00859469Phase 2Results posted
• S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By SurgeryCompletedNCT00770120Phase 2Results posted
• CryoSpray Ablation(tm)in Malignant Airway Disease to Determine Safety, and Tissue Effect in the Lung (ICE the MAD)TerminatedNCT00748085Not applicableResults posted
• An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural MesotheliomaCompletedNCT00738582Phase 2Results posted
• Study of CBP501 + Pemetrexed + Cisplatin on MPM (Phase I/II)CompletedNCT00700336Phase 1/2Results posted
• Phase I Dose-Escalation Study Of Azacitidine In Combination With TemozolomideCompletedNCT00629343Phase 1Results posted
• Carboplatin, Bevacizumab and Pemetrexed in the First-Line Treatment of Patients With Malignant Pleural Mesothelioma (MPM)TerminatedNCT00604461Phase 1/2Results posted
• An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant MesotheliomaTerminatedNCT00597116Phase 2Results posted
• Dasatinib in Treating Patients With Previously Treated Malignant MesotheliomaCompletedNCT00509041Phase 2Results posted
• Pazopanib in Treating Patients With Malignant Pleural MesotheliomaCompletedNCT00459862Phase 2Results posted
• Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or MesotheliomaCompletedNCT00398138Phase 1Results posted
• Sunitinib in Treating Patients With Advanced Malignant Pleural MesotheliomaCompletedNCT00392444Phase 2Results posted
• PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By SurgeryCompletedNCT00365053Phase 2Results posted
• Study of Pemetrexed in Mesothelioma and Lung Cancer Patients With Fluid Around the Lungs or AbdomenCompletedNCT00316225Phase 2Results posted
• Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By SurgeryCompletedNCT00309946Phase 2Results posted
• Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant MesotheliomaCompletedNCT00295503Phase 2Results posted
• S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By SurgeryCompletedNCT00243074Phase 2Results posted
• Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium ThiosulfateTerminatedNCT00165503Phase 2Results posted
• Suberoylanilide Hydroxamic Acid (Vorinostat, MK-0683) Versus Placebo in Advanced Malignant Pleural Mesothelioma (MK-0683-014)CompletedNCT00128102Phase 3Results posted
• Pemetrexed Plus Gemcitabine or Carboplatin for Patients With Advanced Malignant Pleural MesotheliomaCompletedNCT00101283Phase 2Results posted
• Phase II Trial of Neo-Adjuvant Pemetrexed Plus Cisplatin Followed by Surgery and Radiation for Pleural MesotheliomaCompletedNCT00087698Phase 2Results posted
• Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and ChemotherapyCompletedNCT00004547Phase 2Results posted
• Antineoplaston Therapy in Treating Patients With Advanced MesotheliomaTerminatedNCT00003508Phase 2Results posted
• Forceps Versus Cryobiopsy in Undiagnosed Exudative Pleural Effusion Using Rigid ThoracoscopyCompletedNCT07869056Not applicable
• Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage MesotheliomaWithdrawnNCT06654050Phase 2
• Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 2
• Immune Microenvironment and Gene Expression Profiling in MesotheliomaCompletedNCT06581549
• A Study of SGN-MesoC2 in Advanced Solid TumorsTerminatedNCT06466187Phase 1
• A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid TumorsTerminatedNCT06336148Phase 1
• MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural MesotheliomaActive, not recruitingNCT06097728Phase 3
• Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A LossWithdrawnNCT06090318Phase 1/2
• Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer TypesTerminatedNCT06034860Phase 1
• A Phase 1 Clinical Study of NXP900 in Subjects With Advanced CancersActive, not recruitingNCT05873686Phase 1
• Switch-Maintenance Gemcitabine After First-Line Chemotherapy In Patients With Malignant Pleural MesotheliomaCompletedNCT05660616Phase 2
• A Study of T3011 Administered Via Intravenously in Patients With Advanced Solid Tumors.Status unknownNCT05598268Phase 1/2
• Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable CancersWithdrawnNCT05582031Phase 2
• A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid TumorsTerminatedNCT05571839Phase 1
• A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersActive, not recruitingNCT05544929Phase 1
• A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid TumorsCompletedNCT05538572Phase 1
• Effect of HITHOC After Pleurectomy Decortication for Treatment of Malignant Pleural MesotheliomaStatus unknownNCT05508555Not applicable
• Oral AMXT 1501 Dicaprate in Combination With IV DFMOTerminatedNCT05500508Phase 1/2
• Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)CompletedNCT05461430
• Niraparib Efficacy in Patient With Unresectable MesotheliomaCompletedNCT05455424Phase 2
• Immunological Variables Associated to ICI Toxicity in Cancer PatientsStatus unknownNCT05429866Phase 2
• Feasibility Trial of a Personalised Nutrition and Activity Programme for People With Lung Cancer Over 65 YearsCompletedNCT05404022Not applicable
• Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing MesothelinWithdrawnNCT05375825Phase 1
• A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)CompletedNCT05324436
• Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid TumorsActive, not recruitingNCT05311618Phase 1
• Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE)CompletedNCT05308966
• Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including MesotheliomaCompletedNCT05278975Phase 1/2
• Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid TumorsTerminatedNCT05275478Phase 1/2
• A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid TumorsActive, not recruitingNCT05238883Phase 1
• Glypican-1 Expression in Epithelioid Mesothelioma, Adenocarcinoma and SCC of the LungStatus unknownNCT05228795
• Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid TumorsActive, not recruitingNCT05215574Phase 1
• A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function MutationsCompletedNCT05199584Phase 2
• Assessment of Histologic Prognostic Factors in Peritoneal Malignant MesotheliomaStatus unknownNCT05193006
• A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General AnesthesiaStatus unknownNCT05077111Phase 4

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