Meniere Disease clinical trials
The registry lists 74 studies for Meniere Disease across more than 10 countries. 12 are recruiting or about to start. 58 of them are mainly about Meniere Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-16.
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Who runs them
Otonomy, Inc. (9) · Sound Pharmaceuticals, Incorporated (5) · University Hospital, Grenoble (4) · Beijing Tongren Hospital (4) · Osaka University (3) · Otolith Labs (3) · Norfolk and Norwich University Hospitals NHS Foundation Trust (3) · Seoul National University Hospital (2)
What is being tested here
Drugs under test in Meniere Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Corticosteroids 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Dec 2026SPI-1005 for the Treatment of Meniere's Disease (Open Label) · Phase 3 · Sound Pharmaceuticals, Incorporated
- Dec 2026Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease · Northwell Health
- Jan 2027CI Following VS Removal or Labyrinthectomy · Ohio State University
- Apr 2027Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes · IRCCS San Raffaele
Who these studies take
Of the 11 Meniere Disease studies recruiting now, 5 (45%) set no upper age limit and 2 (18%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (36%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 9 (82%) | 9 (82%) |
| 30 | 11 (100%) | 11 (100%) |
| 40 | 11 (100%) | 11 (100%) |
| 50 | 11 (100%) | 11 (100%) |
| 65 | 11 (100%) | 11 (100%) |
| 75 | 10 (91%) | 10 (91%) |
| 85 | 7 (64%) | 7 (64%) |
Across all 74 studies, recruiting or not: 34% stop at 75 or younger and 11% at 65; 5% take children; 0% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Meniere Disease studies take
Of 14 interventional studies with no phase under Meniere Disease, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 16 mo10–42 · 14 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Expanded Access Protocol for SPI-1005Oct 14, 2026NCT07873281
Studies
Recruiting first, then most recently updated. Showing 50 of 74. Browse all 74 → or search them.
- Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic TargetsRecruitingNCT048062821 country
- Treatment of Meniere's Disease With Migraine MedicationsRecruitingNCT05582837Phase 41 country
- Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear DiseaseRecruitingNCT03587701Phase 21 country
- Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With PhenotypesRecruitingNCT075180691 country
- Sleep Disorders and Their Impact on Patients With Ménière's DiseaseRecruitingNCT072995781 country
- Modulating Auditory Symptoms and Vertigo of Meniere's Disease by Non-invasive Mastoid Electric StimulationRecruitingNCT06001593Phase 1/21 country
- Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular TherapyRecruitingNCT05424302Not applicable1 country
- Laser Acupuncture for Meniere DiseaseRecruitingNCT06544434Phase 21 country
- Imaging of Endolymphatic Hydrops at 7T MRIRecruitingNCT043703661 country
- Evaluation of the Diagnostic and Prognostic Efficacy of MRI in Acute Sensorineural Hearing Loss and Ménière's DiseaseRecruitingNCT062781291 country
- The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's DiseaseRecruitingNCT05851508Phase 31 country
- Menier's Disease - Bone Density StudyNot yet recruitingNCT05322538Not applicable
- CI Following VS Removal or LabyrinthectomyActive, not recruitingNCT03795675Not applicable1 country
- Expanded Access Protocol for SPI-1005Temporarily not availableNCT07873281
- Effects of Cervical Mobilization on Dizziness, Balance, and Joint Position Sense in Patients With Meniere's DiseaseCompletedNCT07272473Not applicable1 country
- Safety of APSLXR in Patients Presenting Vertigo of Vestibular Origin or Meniere's DiseaseWithdrawnNCT04674735Phase 1
- CAVA: Dizziness TrialCompletedNCT04026516Not applicable1 country
- SPI-1005 for the Treatment of Meniere's DiseaseCompletedNCT04677972Phase 31 country
- SPI-1005 for the Treatment of Meniere's Disease (Open Label)Active, not recruitingNCT06859788Phase 31 country
- Study to Evaluate SPI-1005 in Adults With Meniere's DiseaseCompletedNCT02603081Phase 1/21 country
- The CAVA Multicentre Dizziness TrialCompletedNCT05984901Not applicable1 country
- Non Enhanced Labyrinth Imaging for the Detection of Endolymphatic Hydrops in Meniere's Disease "NELI Study"CompletedNCT04569175Not applicable1 country
- Evaluation of the OtoBand in Subjects With Self-reported Vertigo to Reduce Severity of Vertigo in a Real-world SettingCompletedNCT04869020Not applicable1 country
- Treating the Symptoms of Vertigo in a Real-world Setting Using the OtoBandCompletedNCT05960786Not applicable1 country
- Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's DiseaseActive, not recruitingNCT04815187Phase 41 country
- A Study of a Mastoid Device in Subjects With Ménière's DiseaseTerminatedNCT03520322Not applicable1 country
- Verification of the Efficacy/safety of the Intratympanic Drug Delivery for Hearing LossCompletedNCT04766853Phase 1/21 country
- Transcutaneous Auricular Vagus Nerve Stimulation for Meniere DiseaseCompletedNCT065445901 country
- Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease OutcomesCompletedNCT04218123Phase 2/31 country
- Transcutaneous Auricular Vagus Nerve Stimulation Treatment on Meniere DiseaseCompletedNCT04686695Not applicable1 country
- Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid InjectionActive, not recruitingNCT04794842Early Phase 11 country
- Comprehensive Evaluation in Patients With Meniere's DiseaseCompletedNCT058446571 country
- SPI-1005 for the Treatment of Patients With Meniere's DiseaseCompletedNCT03325790Phase 21 country
- Pharmacokinetic Profile of Betahistine With and Without Selegiline in Healthy VolunteersCompletedNCT05938517Phase 11 country
- A 6-Month Extension Study of OTO-104 in Meniere's DiseaseTerminatedNCT02768662Phase 31 country
- Study of OTO-104 in Subjects With Unilateral Meniere's DiseaseTerminatedNCT02717442Phase 31 country
- Study of OTO-104 in Subjects With Unilateral Meniere's DiseaseCompletedNCT02612337Phase 31 country
- A 6-Month Extension Study of OTO-104 in Meniere's DiseaseTerminatedNCT02706730Phase 31 country
- Phase 3 Study of OTO-104 in Subjects With Unilateral Meniere's DiseaseCompletedNCT03664674Phase 38 countries
- Transcutaneous Auricular Vagus Nerve Stimulation for Meniere DiseaseCompletedNCT05328895Not applicable1 country
- Meniere Disease and Hearing AidsStatus unknownNCT05582148Not applicable
- Study of Lamotrigine to Treat Ménière's DiseaseCompletedNCT02158585Phase 21 country
- Lamotrigine and Bupropion for Meniere's DiseaseStatus unknownNCT05420350Phase 21 country
- Transcranial Vibrating System for Improving Vestibular Physical TherapyTerminatedNCT03795168Not applicable1 country
- Ménière's Disease RegistryCompletedNCT044385381 country
- Ventilation Tube Insertion for Unilateral Menière's DiseaseStatus unknownNCT04835688Not applicable1 country
- Minimally Invasive Vestibular Neurectomy Versus Tenotomy of the Stapedius and Tensor Tympani Muscles in the Management of Patients With Unilateral Meniere's DiseaseStatus unknownNCT04847700Not applicable1 country
- Acceleration of the Kinetics of Diffusion of Gadolinium in the Perilymphatic Structures of the Inner Ear.Status unknownNCT04949321Not applicable
- Metabolic Disorders and VertigoStatus unknownNCT049359701 country
- What is the Tympanic Membrane Healing Time After Insertion of a Gelfoam PE Tube?CompletedNCT04902963Not applicable