Hypocalcemia clinical trials
The registry lists 98 studies for Hypocalcemia across more than 10 countries. 16 are recruiting or about to start. 51 of them are mainly about Hypocalcemia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Amgen (4) · Calcilytix Therapeutics, Inc., a BridgeBio company (3) · Assiut University (3) · National Institutes of Health Clinical Center (CC) (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Department of Medical Services Ministry of Public Health of Thailand (2) · University Hospital Sestre Milosrdnice (2) · Hôpital Européen Marseille (2)
What is being tested here
Drugs under test in Hypocalcemia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Postoperative Hypocalcemia After Thyroidectomy · Minia University
- Dec 2026Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adults · Amorphical Ltd.
- Oct 2027Ionized Calcium as a Severity Marker in Septic Shock Patients · Assiut University
Who these studies take
Of the 11 Hypocalcemia studies recruiting now, 8 (73%) set no upper age limit and 2 (18%) stop at 75 or younger. 3 (27%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (18%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (27%) | 3 (27%) |
| 18 | 10 (91%) | 10 (91%) |
| 30 | 10 (91%) | 10 (91%) |
| 40 | 10 (91%) | 10 (91%) |
| 50 | 10 (91%) | 10 (91%) |
| 65 | 10 (91%) | 10 (91%) |
| 75 | 10 (91%) | 10 (91%) |
| 85 | 9 (82%) | 9 (82%) |
Across all 98 studies, recruiting or not: 23% stop at 75 or younger and 14% at 65; 30% take children; 5% are for women only and 1% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypocalcemia studies take
Of 20 interventional studies with no phase under Hypocalcemia, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 23 mo16–39 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting1
- NIRAF-Guided Parathyroid Identification During ThyroidectomyNov 6, 2026NCT07617584
Studies
Recruiting first, then most recently updated. Showing 50 of 98. Browse all 98 → or search them.
- NIRAF-Guided Parathyroid Identification During ThyroidectomyRecruitingNCT07617584Not applicable1 country
- Postoperative Hypocalcemia After ThyroidectomyRecruitingNCT074280571 country
- Ionized Calcium as a Severity Marker in Septic Shock PatientsNot yet recruitingNCT07812051
- COMPARISON OF THE EFFICACY BETWEEN PREOPERATIVE CALCIUM & VITAMIN D3 VERSUS CALCIUM SUPPLEMENTATION ALONE TO PREVENT POST OPERATIVE SYMPTOMATIC HYPOCALCEMIA AFTER TOTAL THYROIDECTOMY IN EUTHYROID PATIENTSNot yet recruitingNCT07597096Not applicable1 country
- Pharmacokinetics, Efficacy, and Safety of Encaleret in Pediatric Participants With Autosomal Dominant Hypocalcemia Type 1 (ADH1)RecruitingNCT07080385Phase 2/32 countries
- Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total ThyroidectomyRecruitingNCT04785443Phase 31 country
- Comparing PTeye-assisted Versus Conventional Total ThyroidectomyRecruitingNCT07416149Not applicable1 country
- Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence ImagingRecruitingNCT070103411 country
- WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-MakingNot yet recruitingNCT07043010Not applicable1 country
- Usefulness of ICG Angiography-Guided Thyroidectomy for Preserving Parathyroid FunctionRecruitingNCT05573828Not applicable1 country
- Calcium Administration in Life-saving Management During Massive HemorrhageNot yet recruitingNCT06820645Phase 2/3
- Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol SupplementationRecruitingNCT04775381Phase 31 country
- COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG WearableEnrolling by invitationNCT067635491 country
- The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and HypocalcaemiaRecruitingNCT05732883Phase 21 country
- Chinese CKD-MBD Prevalence Survey (CRISS-MBD)RecruitingNCT047149181 country
- Registry for Hypoparathyroidism WuerzburgRecruitingNCT055855931 country
- Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in AdultsActive, not recruitingNCT06547151Phase 21 country
- Therapeutic Effects of Oat-based Cereal on Fetomaternal Outcomes Among Hypocalcemic Antenatal WomenCompletedNCT07751198Not applicable1 country
- Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1Active, not recruitingNCT05680818Phase 310 countries
- Ionized Calcium Changes for Predicting Postoperative Hypocalcemia After Total ThyroidectomyCompletedNCT077018241 country
- ADH1 and ADH2 Disease Monitoring Study (DMS)Active, not recruitingNCT0522728713 countries
- Empiric Calcium in Massive TransfusionWithdrawnNCT05953376Phase 3
- PTH-independent Effects of EncaleretCompletedNCT05735015Phase 21 country
- Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic HypoparathyroidismCompletedNCT00743782Phase 21 country
- Intraoperative Methylene Blue Spray for the Identification and Preservation of Vital Structures in ThyroidectomyCompletedNCT07395388Not applicable1 country
- Predicting Factors of Post-Total Thyroidectomy HypocaӏcemiaCompletedNCT072115811 country
- A Comparative Analysis of Hypocalcemia Incidence in Patients Undergoing Thyroidectomy: Ligasure vs Conventional Ligation of Vessels by Knot TyingCompletedNCT06716632Not applicable1 country
- Prevention of Postoperative Hypocalcemia of Oral Vitamin D Supplementation Before Total ThyroidectomyCompletedNCT05216419Phase 41 country
- Clinical Assessment of Low Calcium In traUMa (CALCIUM)Active, not recruitingNCT058852561 country
- Calcium+Calcitriol Versus PTH for the Prevention of Hypocalcemia in Thyroidectomy. Randomized Clinical TrialCompletedNCT05252884Not applicable1 country
- Hypoglycemia Prevention and Awareness ProgramActive, not recruitingNCT06775288Not applicable1 country
- Effect of Vitamin D Supplement on Disease Activity in SLECompletedNCT05260255Not applicable1 country
- Autofluorescence vs Clinical Assessment of Parathyroid Glands During Thyroid SurgeryCompletedNCT04509011Not applicable4 countries
- HEXT (Hypo EXTended): Effect of PTH on Skeleton in HypoparathyroidismCompletedNCT01199614Phase 31 country
- Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in ParturientsCompletedNCT05973747Early Phase 11 country
- Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi HospitalCompletedNCT04967469Not applicable1 country
- Near-infrared Autofluorescence (NIRAF)-Guided Total Thyroidectomy: Impact in Low-volume, Non-parathyroid InstitutionsCompletedNCT05043584Not applicable1 country
- The Incidence of Hypocalcemia in Pregnant Women at Siriraj HospitalActive, not recruitingNCT06160479Not applicable1 country
- Complications After Thyroid Surgeries: 10 Years' ExperienceCompletedNCT056993041 country
- A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)CompletedNCT03324880Phase 413 countries
- Citrate Effects and Bone Density in Long-Term Apheresis DonorsCompletedNCT000730601 country
- Effect of Preoperative High-dose Cholecalciferol in Prevention of Post-thyroidectomy HypocalcaemiaStatus unknownNCT05586529Not applicable1 country
- Fibroblast Growth Factor 23 and Sclerostin in Relation to Calcium in COVID-19 PatientsCompletedNCT052754911 country
- Effect of Phototherapy on Serum CalciumCompletedNCT042156011 country
- Studies of States With Resistance to Vitamin D and Parathyroid HormoneCompletedNCT000012421 country
- Comparison of Liagure Safety in Thyroidectomy With Conventional ThyroidectomyStatus unknownNCT05684536Not applicable
- Evaluation of iMmune Function in Post-surgical and AuToimmune HYpoparathyroidism (EMPATHY)CompletedNCT040593801 country
- Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa).CompletedNCT04750460Phase 31 country
- A Trial to Evaluate Safety and Efficacy of RP-L401-0120 in Subjects With Infantile Malignant OsteopetrosisTerminatedNCT04525352Phase 11 country
- Thymus Transplantation Dose in DiGeorge #932CompletedNCT00576836Phase 21 country