Hypertensive Crisis clinical trials
The registry lists 31 studies for Hypertensive Crisis across 9 countries. 9 are recruiting or about to start. 18 of them are mainly about Hypertensive Crisis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-22.
Get an email when these change. Save the Hypertensive Crisis studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Brigham and Women's Hospital (9) · Centre Hospitalier de PAU (2) · Nanjing Yoko Biomedical Co., Ltd. (1) · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. (1) · Ankara City Hospital Bilkent (1) · Shenzhen People's Hospital (1) · Qilu Pharmaceutical (Hainan) Co., Ltd. (1) · Saglik Bilimleri Universitesi (1)
What is being tested here
Drugs under test in Hypertensive Crisis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Clevidipine | 2 | 3 | 3 |
| Tonlamarsen | 1 | 0 | 1 |
| Eculizumab | 1 | 1 | 1 |
| Labetalol | 0 | 0 | 3 |
| Nicardipine | 0 | 0 | 2 |
| Nifedipine | 0 | 0 | 1 |
Drug classes tested here Calcium channel blockers 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Nov 2026Optic Nerve Sheath Diameter in Hypertensive Emergency · Leiden University Medical Center
- Dec 2026Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension · Kardigan, Inc.
Who these studies take
Of the 5 Hypertensive Crisis studies recruiting now, 5 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 5 (100%) | 5 (100%) |
Across all 31 studies, recruiting or not: 16% stop at 75 or younger and 3% at 65; 3% take children; 3% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- Determinants of Malignant Hypertension Onset and Related Target Organ Damages: the HAMA BiobankRecruitingNCT066293631 country
- Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe HypertensionRecruitingNCT07511361Phase 21 country
- Home Hospital for Suddenly Ill AdultsRecruitingNCT03524222Not applicable1 country
- HYPERTENSIVE CRISIS AND ATMOSPHERIC PRESSURE RELATIONSHIPRecruitingNCT066356031 country
- Optic Nerve Sheath Diameter in Hypertensive EmergencyNot yet recruitingNCT06286696
- The Value of TOI in Evaluating Renal Function Damage in Hypertensive Emergency PatientsNot yet recruitingNCT06201572
- Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic SyndromeRecruitingNCT05726916Phase 31 country
- a Study Evaluating the Safety and Efficacy of Clevidipine for Patients Who With Hypertensive Emergency and Sub-emergencyNot yet recruitingNCT05922436Phase 3
- A Study of Clevidipine Butyrate Injectable Emulsion in the Treatment of Hypertensive Emergency and Sub-emergencyNot yet recruitingNCT05783557Phase 3
- The Use of Virtual Reality and Music Therapy for Hypertensive UrgencyCompletedNCT07272486Not applicable1 country
- Postpartum Hypertension StudyTerminatedNCT05139238Phase 41 country
- Serum Potassium Prediction Using Machine Learning and Single-lead ECGWithdrawnNCT074937981 country
- Prediction of 30-Day Readmission Using Machine LearningCompletedNCT048493121 country
- Prediction of Patient Deterioration Using Machine LearningCompletedNCT050457421 country
- Prediction of Expected Length of Hospital Stay Using Machine LearningWithdrawnNCT047843511 country
- Nicardipine vs. LabetalolCompletedNCT07277283Phase 41 country
- Rural Hospital-Level Care at Home for Acutely Ill AdultsCompletedNCT05256303Not applicable2 countries
- Rural Home Hospital: Proof of ConceptCompletedNCT04531280Not applicable1 country
- Interrupters of VAscular daMAge in Malignant HypertensionCompletedNCT049910771 country
- Clinical Relevance of Nicardipine Induced Hypoxemia in the Intensive Care UnitStatus unknownNCT051552021 country
- Clinical Study of Clevidipine Butyrate Injection in the Treatment of Hypertensive Emergency and Sub-emergencyStatus unknownNCT05044364Phase 31 country
- Improving Acute Hypertension Management Through Emergency Department ChecklistCompletedNCT04553653Not applicable1 country
- Safety and Efficacy Study of Clevidipine Butyrate Injection in Hypertensive EmergenciesStatus unknownNCT04670809Phase 31 country
- Remote Physician Care for Home Hospital PatientsCompletedNCT04080570Not applicable1 country
- Effects of Saline on Circulation in ChildrenTerminatedNCT01668277Phase 21 country
- Effect of Pursed-Lip Breathing on Blood Pressure and Heart RateCompletedNCT04572672Not applicable1 country
- Hospital-Level Care at Home for Acutely Ill AdultsCompletedNCT03203759Not applicable1 country
- A ED-based Intervention to Improve Antihypertensive AdherenceCompletedNCT02672787Not applicable1 country
- Telemedical Versus Conventional Emergency Care of Hypertensive EmergenciesCompletedNCT029248051 country
- Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency DepartmentCompletedNCT00765648Phase 41 country
- Risk Factors of Hypertensive UrgenciesCompletedNCT004212391 country