Hypertension, Pulmonary: all 1,119 studies

Page 3 of 12. Open to participants first (236), then studies with results posted, then the rest; newest registration first within each.

• Pulmonary Hypertension Biorepository and RegistryRecruitingNCT04808596
• Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension PatientsRecruitingNCT04756076
• Inflammatory Profiling in Chronic Lung DiseaseRecruitingNCT04654767
• Prospective Registry and Biobank for Long-term Observational Studies in Adult Patients with Pulmonary HypertensionRecruitingNCT04654650
• Evaluating Infrasonic HemodynographyRecruitingNCT04636892Not applicable
• Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary DiseaseRecruitingNCT04624490Phase 1
• Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension SystemRecruitingNCT04555161Not applicable
• Arrhythmias in Pulmonary Hypertension Assessed by Continuous Long-term Cardiac MonitoringRecruitingNCT04554160
• Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary HypertensionRecruitingNCT04484675Phase 4
• Giessen Pulmonary Hypertension in Lung Cancer RegistryRecruitingNCT04467333
• RV Conductance Catheter Assessment During Balloon Pulmonary AngioplastyRecruitingNCT04444973
• Infusion of Allogeneic Mesenchymal Stem Cells in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary InvolvementAvailableNCT04432545
• Training Single ArmRecruitingNCT04224025Not applicable
• Giessen Pulmonary Hypertension Registry and BiobankRecruitingNCT04145024
• Feasibility of Novel Clinical Trial Infrastructure, Design and Technology for Early Phase Studies in Patients With Pulmonary Hypertension (FIT-PH)RecruitingNCT04078243
• Pulmonary Hypertension Association RegistryRecruitingNCT04071327
• DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PLRecruitingNCT03959748
• Development of Novel Physiological CMR Methods in Health and DiseaseRecruitingNCT03854071Not applicable
• Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial HypertensionRecruitingNCT03835676Phase 4
• Pedometers and Walking Tests for Pulmonary Hypertension PatientsRecruitingNCT03810482Not applicable
• A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label ExtensionEnrolling by invitationNCT03683186Phase 3
• Autologous Stem Cell Transplantation in Patients With Systemic SclerosisRecruitingNCT03630211Phase 2
• Endtidal Carbon Dioxide for Earlier Detection of Pulmonary HypertensionEnrolling by invitationNCT03388476
• New Orleans Pulmonary Hypertension BiobankRecruitingNCT03269630
• Registration Study for Rare Type of Pulmonary HypertensionRecruitingNCT03169010
• MRI and Computational Simulation Cardiology StudyEnrolling by invitationNCT03149341
• Feto-Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic HerniaRecruitingNCT02986087Not applicable
• Pediatric Pulmonary Hypertension Network (PPHNet) Informatics RegistryRecruitingNCT02249923
• the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary HypertensionRecruitingNCT02061787
• Natural History Study of Biomarkers in Pulmonary Arterial HypertensionRecruitingNCT01730092
• Non-contrast Enhanced Cardiac Magnetic Resonance Imaging in the Diagnosis and Classification of Pulmonary HypertensionEnrolling by invitationNCT01725763Not applicable
• Database for Clinical and Anamnestic Data in Pulmonary HypertensionRecruitingNCT01607502
• Investigation of Dysynchrony in Patients With Pulmonary HypertensionEnrolling by invitationNCT01571700
• Early Diagnosis of Pulmonary Hypertension in Patients With Inflammatory Rheumatic Connective Tissue DiseasesRecruitingNCT01387035
• COMPERA / COMPERA-KIDSRecruitingNCT01347216
• Natural History of Sickle Cell DiseaseRecruitingNCT00081523
• Treatment of Persistent Pulmonary Hypertension in Neonates With Nebulized Magnesium SulfateCompletedNCT06603766Phase 2/3Results posted
• Extension Study of Efficacy and Safety of LTP001 in Pulmonary Arterial Hypertension ParticipantsTerminatedNCT05764265Phase 2Results posted
• First-in-human Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of C106 in Healthy SubjectsCompletedNCT05427253Phase 1Results posted
• Piloting Mindfulness Meditation Program for Underserved Racial Minority Adults With Pulmonary HypertensionCompletedNCT05387889Not applicableResults posted
• Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAHTerminatedNCT05339087Phase 2Results posted
• Cognitive Behavioral Therapy and Light TherapyCompletedNCT05337943Not applicableResults posted
• Study of Efficacy and Safety of LTP001 in Pulmonary Arterial HypertensionTerminatedNCT05135000Phase 2Results posted
• Investigation of H01 in Adults With Pulmonary Hypertension Including Interstitial Lung Disease (The SATURN Study).CompletedNCT05128929Phase 2Results posted
• Evaluation of the Usefulness of Adopting Remote, Mobile-based 6MWT Among Hospital Outpatients (the 6-APPnow), Within the Constraints Imposed by the SARS-COV2 PandemicCompletedNCT05096819Results posted
• A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16)CompletedNCT04945460Phase 2Results posted
• The Role of Matrix Metalloproteinase 2 and 9 Enzymes in Developing Chronic Thromboembolic Pulmonary HypertensionCompletedNCT04773028Results posted
• A Study of the Efficacy and Safety of Frespaciguat (MK-5475) in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)CompletedNCT04732221Phase 2/3Results posted
• Evaluation of a New 6 Minute Walk Test Smartphone App in Patients With Pulmonary HypertensionCompletedNCT04633538Results posted
• A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)CompletedNCT04576988Phase 3Results posted
• A Study of Selexipag in Participants Who Participated in a Previous Selexipag StudyCompletedNCT04565990Phase 3Results posted
• Frespaciguat (MK-5475) in Participants With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD) (MK-5475-006)CompletedNCT04370873Phase 1Results posted
• A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial HypertensionActive, not recruitingNCT04175600Phase 3Results posted
• Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult ParticipantsCompletedNCT04095286Phase 1Results posted
• Study of Ralinepag on Exercise Capacity by Cardiopulmonary Exercise Testing (CPET) in WHO Group 1 PH SubjectsTerminatedNCT04084678Phase 3Results posted
• A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral SelexipagTerminatedNCT03942211Phase 2Results posted
• Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)TerminatedNCT03794583Phase 3Results posted
• A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional TreatmentTerminatedNCT03689244Phase 3Results posted
• Enteral L Citrulline Supplementation in Preterm Infants - Safety, Efficacy and DosingCompletedNCT03649932Phase 1Results posted
• Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary DysplasiaTerminatedNCT03576885Phase 1/2Results posted
• Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary HypertensionCompletedNCT03554291Phase 2Results posted
• L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary DysplasiaTerminatedNCT03542812Early Phase 1Results posted
• Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEFCompletedNCT03541603Phase 2Results posted
• Tamoxifen Therapy to Treat Pulmonary Arterial HypertensionCompletedNCT03528902Phase 2Results posted
• A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)TerminatedNCT03496623Phase 3Results posted
• Effect of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung UltrasonographyTerminatedNCT03490916Phase 4Results posted
• Investigation of the Safety and Pharmacology of Dry Powder Inhalation of TreprostinilCompletedNCT03399604Phase 3Results posted
• Cardiometabolic Disease and Pulmonary HypertensionTerminatedNCT03349775Early Phase 1Results posted
• The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial HypertensionCompletedNCT03273387Phase 2/3Results posted
• Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)TerminatedNCT03273257Phase 2Results posted
• Effect of Inhaled Albuterol in Pulmonary HypertensionCompletedNCT03270332Phase 2Results posted
• Pulmonary Hypertension and Anastrozole TrialCompletedNCT03229499Phase 2Results posted
• Urban Zen Integrative Therapy for Persons With Pulmonary HypertensionCompletedNCT03194438Not applicableResults posted
• A Dose-escalation Study in Subjects With Pulmonary Arterial Hypertension (PAH)CompletedNCT03177603Phase 2Results posted
• The Right Ventricular Pulmonary Circulation Continuum in Mitral Valve Disease StudyCompletedNCT03155373Results posted
• VentaProst Versus Conventionally-Administered Aerosolized Epoprostenol in Patients Undergoing Cardiac Surgery With CPBCompletedNCT03122730Phase 2Results posted
• Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGERTerminatedNCT03068130Phase 3Results posted
• Outpatient Vasodilator Assessment Using Iloprost in Pulmonary HypertensionTerminatedNCT03044314Phase 4Results posted
• Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEFTerminatedNCT03043651Phase 3Results posted
• Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection FractionTerminatedNCT03037580Phase 3Results posted
• Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection FractionCompletedNCT03015402Phase 2Results posted
• Study of Angiogenic Cell Therapy for Progressive Pulmonary HypertensionTerminatedNCT03001414Phase 2/3Results posted
• Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial HypertensionTerminatedNCT02981082Phase 1Results posted
• Auto-PAP for Pulmonary Hypertension Treatment in Decompensated HF Patients With Sleep Apnea.CompletedNCT02963597Not applicableResults posted
• Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary HypertensionCompletedNCT02951429Phase 2Results posted
• Markers of Inflammation and Lung Recovery in ECMO Patients for PPHNCompletedNCT02940327Results posted
• Targeting Right Ventricle in Pulmonary Hypertension GileadCompletedNCT02829034Phase 4Results posted
• A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy SubjectsCompletedNCT02688387Phase 1Results posted
• Macitentan in Pulmonary Hypertension of Sickle Cell DiseaseTerminatedNCT02651272Phase 2Results posted
• An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFETerminatedNCT02633293Phase 2/3Results posted
• Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFECompletedNCT02630316Phase 2/3Results posted
• Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial HypertensionCompletedNCT02587325Phase 1Results posted
• Riociguat in Children With Pulmonary Arterial Hypertension (PAH)Active, not recruitingNCT02562235Phase 3Results posted
• Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device ImplantationCompletedNCT02554903Phase 2Results posted
• Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) PatientsCompletedNCT02551653Phase 1Results posted
• Sildenafil in Heart Failure With Reactive Pulmonary HypertensionTerminatedNCT02304705Phase 4Results posted
• Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH)CompletedNCT02290613Phase 2Results posted
• Remodulin as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the NewbornTerminatedNCT02261883Phase 2Results posted
• Measuring Outcomes In Patients With Pulmonary Arterial Hypertension Not on Active Treatment (MOTION)CompletedNCT02191137Phase 4Results posted
• Inhaled Aerosolized Prostacyclin for Pulmonary Hypertension Requiring Inhaled Nitric OxideTerminatedNCT02170519Phase 4Results posted

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