Hyperparathyroidism, Secondary clinical trials
The registry lists 188 studies for Hyperparathyroidism, Secondary across more than 10 countries. 15 are recruiting or about to start. 122 of them are mainly about Hyperparathyroidism, Secondary (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its narrower condition Chronic Kidney Disease-Mineral and Bone Disorder too: 246 studies, 33 open.
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Who runs them
Amgen (33) · Abbott (13) · AbbVie (prior sponsor, Abbott) (12) · OPKO Health, Inc. (8) · Kyowa Kirin Co., Ltd. (7) · OPKO IP Holdings II, Inc. (5) · KAI Pharmaceuticals (5) · Shanghai Hengrui Pharmaceutical Co., Ltd. (5)
What is being tested here
Drugs under test in Hyperparathyroidism, Secondary studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5, phase 3 first
- Nov 2026Study of MT1013 for the Treatment of Patients With Secondary Hyperparathyroidism · Phase 3 · Shaanxi Micot Pharmaceutical Technology Co., Ltd.
- Jun 2027A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis · Phase 3 · Amgen
- Jun 2027Precision Medicine Approaches to Renal Osteodystrophy · Thomas Nickolas
- Sep 2027Hyperparathyroidism and Dialysis Adequacy in Hemodialysis Patients · Assiut University
- Oct 2027Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants · OPKO Health, Inc.
Who these studies take
Of the 10 Hyperparathyroidism, Secondary studies recruiting now, 5 (50%) set no upper age limit and 4 (40%) stop at 75 or younger. 4 (40%) take children under 18. 1 (10%) are for women only and 0 (0%) for men only; 1 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (40%) | 4 (40%) |
| 18 | 7 (70%) | 6 (60%) |
| 30 | 7 (70%) | 6 (60%) |
| 40 | 7 (70%) | 6 (60%) |
| 50 | 7 (70%) | 6 (60%) |
| 65 | 7 (70%) | 6 (60%) |
| 75 | 6 (60%) | 5 (50%) |
| 85 | 5 (50%) | 5 (50%) |
Across all 188 studies, recruiting or not: 21% stop at 75 or younger and 13% at 65; 14% take children; 2% are for women only and 1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hyperparathyroidism, Secondary studies take
Of 21 phase 3 interventional studies under Hyperparathyroidism, Secondary, half reached primary completion within 22 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 22 mo14–31 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 188. Browse all 188 → or search them.
- Study of MT1013 for the Treatment of Patients With Secondary HyperparathyroidismRecruitingNCT07122401Phase 31 country
- A Study of PLS240 in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on HemodialysisNot yet recruitingNCT07890584Phase 31 country
- Hyperparathyroidism and Dialysis Adequacy in Hemodialysis PatientsNot yet recruitingNCT07820150
- A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving HemodialysisRecruitingNCT03969329Phase 312 countries
- Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric ParticipantsRecruitingNCT07494045Phase 21 country
- Precision Medicine Approaches to Renal OsteodystrophyRecruitingNCT058809141 country
- Parathyroid Tumor Clonal StatusRecruitingNCT059978101 country
- A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on HemodialysisRecruitingNCT03633708Phase 310 countries
- Study of MT1013 Injection for the Treatment of Secondary Hyperparathyroidism (SHPT) Patients With Chronic Kidney Disease Undergoing Maintenance DialysisRecruitingNCT06976177Phase 21 country
- A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.RecruitingNCT061260161 country
- Intraoperative Parathyroid Hormone Monitoring to Guide Surgery in Renal hyperparathyroIdismNot yet recruitingNCT06542315Not applicable1 country
- The Effect of Increasing Dialysate Calcium on T50 in Subjects With Secondary Hyperparathyroidism and ESKDNot yet recruitingNCT06398002Phase 2
- Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal FailureNot yet recruitingNCT06378931
- Chinese CKD-MBD Prevalence Survey (CRISS-MBD)RecruitingNCT047149181 country
- Total Parathyroidectomy With Autotransplantation Versus Total Parathyroidectomy Alone for Secondary HyperparathyroidismRecruitingNCT04922892Not applicable1 country
- Cardiovascular Mortality Prediction in Maintenance Hemodialysis PatientsCompletedNCT077691901 country
- A Mass Balance Study of [14C] MT1013 in Hemodialysis Subjects With Secondary HyperparathyroidismCompletedNCT07284043Phase 11 country
- MT1013 Injection for the Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney DiseaseCompletedNCT06690242Phase 21 country
- Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on DialysisTerminatedNCT02859896Phase 32 countries
- A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)TerminatedNCT04064827Phase 32 countries
- Investigating the Safety and Efficacy of SHR6508 Injection in the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients : A Multicenter, Long-term Clinical TrialCompletedNCT06236295Phase 21 country
- A Mass Balance Study of [14C] SHR6508 in Chinese Hemodialysis Subjects With Secondary HyperparathyroidismCompletedNCT06877247Phase 11 country
- A Clinical Study Evaluating the Safety, Tolerability, and Efficacy of MT1013 in Hemodialysis Subjects With Secondary HyperparathyroidismCompletedNCT06747247Phase 21 country
- The Trial of SHR6508 in Secondary HyperparathyroidismCompletedNCT06434961Phase 31 country
- Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1CompletedNCT05832931Phase 36 countries
- Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2CompletedNCT05836220Phase 36 countries
- Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary HyperparathyroidismTerminatedNCT05543928Phase 31 country
- Cinacalcet to Treat Hypercalcemia in Renal Transplant RecipientsTerminatedNCT00415584Phase 1/21 country
- LEO 27847 - Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in Secondary Hyperparathyroidism PatientsCompletedNCT01167309Phase 12 countries
- Safety and Efficacy of CTAP101 to Treat Secondary Hyperparathyroidism in Stage 3 or 4 CKD and Vitamin D InsufficiencyCompletedNCT01704079Phase 31 country
- Safety and Efficacy of CTAP101 to Treat Secondary Hyperparathyroidism in Stage 3 or 4 CKD and Vitamin D InsufficiencyCompletedNCT01651000Phase 31 country
- Single-Cell Sequence Technology Used to Reveal Heterogeneity of Secondary HyperparathyroidismActive, not recruitingNCT061306831 country
- A Study to Evaluate the Effect of ASP7991 in Secondary Hyperparathyroidism Patients Undergoing HemodialysisCompletedNCT02133404Phase 21 country
- Impact of Parathyroidectomy on Vascular Calcification and Clinical Outcome in Hemodialysis PatientsCompletedNCT037241881 country
- Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPTCompletedNCT03123406Phase 41 country
- Impact of Parathyroidectomy on Cardiovascular Calcification in Dialysis-dependent PatientsCompletedNCT039373491 country
- Changes in Cardiac Functions in Patients Treated With Parathyroidectomy for Secondary HyperparathyroidismCompletedNCT061874801 country
- Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. ParicalcitolTerminatedNCT01725113Phase 41 country
- Diagnostic Accuracy of 3T MR for Secondary Hyperparathyroidism Comparison With 4DCTCompletedNCT055407951 country
- A Trial of SHR6508 in Secondary HyperparathyroidismCompletedNCT05221008Phase 11 country
- A Study of SHR6508 in Secondary HyperparathyroidismStatus unknownNCT05663411Phase 21 country
- FGF-23 (Fibroblast Growth Factor 23) Regulation in Chronic Kidney DiseaseCompletedNCT00999037Not applicable1 country
- Subtotal Parathyroidectomy or Total Parathyroidectomy With Autograft in Chronic Kidney Disease Patients Under DialysisActive, not recruitingNCT02464072Not applicable1 country
- Repeated-dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of CTAP101, Immediate-release Calcifediol, High-dose Cholecalciferol, and Paricalcitol Plus Low-dose Cholecalciferol in Patients With Secondary Hyperparathyroidism, Chronic Kidney Disease 3-4 and Vitamin D InsufficiencyCompletedNCT03588884Phase 41 country
- Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa).CompletedNCT04750460Phase 31 country
- E.V.O.L.V.E. Trial™: EValuation Of Cinacalcet Hydrochloride (HCl) Therapy to Lower CardioVascular EventsCompletedNCT00345839Phase 3
- Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After ParathyroidectomyCompletedNCT05382988Phase 3
- Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its TreatmentCompletedNCT05347082Not applicable1 country
- Study of KHK7580 in Subjects With Secondary Hyperparathyroidism in AsiaCompletedNCT03822507Phase 34 countries
- Suspected Deficient Activation of Vitamin D in Patients With Secondary HyperparathyroidismCompletedNCT00754442Not applicable1 country