Hyperemesis Gravidarum clinical trials
The registry lists 40 studies for Hyperemesis Gravidarum across more than 10 countries. 6 are recruiting or about to start. 31 of them are mainly about Hyperemesis Gravidarum (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.
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Who runs them
Kayseri Education and Research Hospital (3) · The Hospital for Sick Children (2) · Haukeland University Hospital (2) · Nawaz Sharif Medical College (1) · Müge Keskin (1) · University College Cork (1) · Bahria University (1) · Centre Hospitalier de Saint-Denis (1)
What is being tested here
Drugs under test in Hyperemesis Gravidarum studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ginger extract | 1 | 0 | 1 |
| Metformin | 1 | 0 | 1 |
| Doxylamine succinate | 0 | 1 | 2 |
| Doxylamine | 0 | 1 | 2 |
| Mirtazapine | 0 | 0 | 2 |
| Haloperidol | 0 | 0 | 1 |
| Gabapentin | 0 | 0 | 1 |
| Metoclopramide | 0 | 0 | 1 |
| Clonidine | 0 | 1 | 1 |
| Ondansetron | 0 | 0 | 1 |
Drug classes tested here Antiemetics 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Jun 2027Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up · Assistance Publique - Hôpitaux de Paris
Who these studies take
Of the 3 Hyperemesis Gravidarum studies recruiting now, 1 (33%) set no upper age limit and 2 (67%) stop at 75 or younger. 0 (0%) take children under 18. 3 (100%) are for women only and 0 (0%) for men only; 2 (67%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 3 (100%) | 0 (0%) |
| 30 | 3 (100%) | 0 (0%) |
| 40 | 3 (100%) | 0 (0%) |
| 50 | 2 (67%) | 0 (0%) |
| 65 | 1 (33%) | 0 (0%) |
| 75 | 1 (33%) | 0 (0%) |
| 85 | 1 (33%) | 0 (0%) |
Across all 40 studies, recruiting or not: 57% stop at 75 or younger and 57% at 65; 15% take children; 95% are for women only and 0% for men only; 45% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 40 of 40. search them.
- Diagnostic and Psychometric Validation of the FRENCH HELP Scale in Hyperemesis GravidarumNot yet recruitingNCT077670711 country
- Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-UpRecruitingNCT06615843Not applicable1 country
- Hyperemesis Gravidarum Risk Reduction With MetforminRecruitingNCT07129473Phase 1/21 country
- Tablet Ginger Versus Tablet Doxylamine Succinate in Control of Nausea and Vomiting in PregnancyNot yet recruitingNCT06772974Not applicable1 country
- Effects Of Emotional Freedom Technique and Hypermesis GravidarumNot yet recruitingNCT06442813Not applicable1 country
- The Effect of Mint Flavored Chewing Gum on Hyperemesis Gravidarum Nausea Vomiting Severity, Coping With Stress and Anxiety Level in Pregnants With Hyperemesis GravidarumRecruitingNCT06266819Not applicable1 country
- Prevalence of Hyperemesis GravidarumCompletedNCT064150841 country
- Development of a Management Model for Hyperemesis in Pregnant Women Through the "Vibratory Emesis Massage"CompletedNCT07613814Not applicable1 country
- Date Fruit Benefits to Treat Morning Sickness in First Trimester of PregnancyActive, not recruitingNCT07354529Not applicable1 country
- Management of Nausea and Vomiting in Pregnancy and Hyperemesis Gravidarum: Evaluation of Clinical Practices in Five Maternity Hospitals in Île-de-FranceCompletedNCT068410291 country
- First Trimester Resistin Levels in HGCompletedNCT06757374Not applicable1 country
- Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP)WithdrawnNCT05452174Phase 1/21 country
- Pepsinogen-1 Serum Levels in Hyperemesis GravidarumCompletedNCT065817961 country
- Chewing Gum Containing Vitamin-c to Treat Emesis GravidarumCompletedNCT04284696Not applicable1 country
- Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC)CompletedNCT03056482Phase 41 country
- Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of PregnancyCompletedNCT05098067Phase 21 country
- Inflammation Markers in Hyperemesis GravidarumCompletedNCT062458111 country
- MinSafeStart - Decision Aid Tool for Better Treatment of Nausea and Vomiting During PregnancyCompletedNCT04719286Not applicable1 country
- Use of Hypnosis in Hyperemesis GravidarumCompletedNCT04828967Not applicable1 country
- The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis GravidarumStatus unknownNCT05829473Not applicable
- Use of the Modified PUQE Score on Admitted Cases of Hyperemesis Gravidarum (HG) to Guide Response to TreatmentCompletedNCT047859111 country
- Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis GravidarumCompletedNCT02163434Phase 21 country
- The Levels of the Orexin, Galanin and aMSH and CART in Patients With Hyperemesis GravidarumCompletedNCT054460251 country
- Validating the Effect og Ondansetron and Mirtazapine in Treating Hyperemesis GravidarumTerminatedNCT03785691Phase 21 country
- Acupressure in Hyperemesis GravidarumCompletedNCT05175079Not applicable1 country
- Gallbladder Functions & Serum Cholecystokinin Levels in Women Diagnosed With Hyperemesis GravidarumCompletedNCT039501671 country
- The Efficacy Of Diclectin® For Nausea And Vomiting Of PregnancyCompletedNCT00614445Phase 31 country
- Hyperemesis Gravidarum and OsteoporosisCompletedNCT03127293
- Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance TestCompletedNCT02963753
- Endothelial Dysfunction in Hyperemesis GravidarumStatus unknownNCT029893371 country
- Nutritional Markers in Normal and Hyperemesis PregnanciesStatus unknownNCT026191881 country
- Bone Health in Hyperemesis GravidarumStatus unknownNCT028624961 country
- Pre-emptive Treatment of Severe Nausea and Vomiting of PregnancyCompletedNCT00293644Phase 31 country
- The Association of Helicobacter Pylori in the Pathogenesis of Hyperemesis Gravidarum in Pregnant WomenCompletedNCT02830321
- Assessment of the Relationship Between Affective Temperament and the Severity of Nausea and Vomiting in Early PregnancyCompletedNCT02541682Not applicable1 country
- Does Thiamine Help Vomiting and Nausea in Pregnancy?TerminatedNCT00861523Phase 31 country
- Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in NorwegianCompletedNCT018368351 country
- Improving Multivitamin Supplementation to Pregnant WomenCompletedNCT02300155Phase 41 country
- Transdermal Clonidine in the Treatment of Severe Hyperemesis GravidarumCompletedNCT01559012Phase 31 country
- Management of Nausea and Vomiting of PregnancyCompletedNCT00795561Not applicable1 country