Hereditary Autoinflammatory Diseases clinical trials
The registry lists 12 studies for Hereditary Autoinflammatory Diseases across more than 10 countries. 5 are recruiting or about to start. 8 of them are mainly about Hereditary Autoinflammatory Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 3 narrower conditions too, such as Behcet Syndrome: 239 studies, 76 open.
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Who runs them
National Human Genome Research Institute (NHGRI) (1) · Wenjie Zheng (1) · Connecticut Children's Medical Center (1) · Novartis Pharmaceuticals (1) · Oregon Health and Science University (1) · Assistance Publique - Hôpitaux de Paris (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
What is being tested here
Drugs under test in Hereditary Autoinflammatory Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Thalidomide | 1 | 0 | 1 |
| Lanadelumab | 0 | 0 | 1 |
| Canakinumab | 0 | 0 | 1 |
| Lacteol | 0 | 0 | 1 |
| Bifidobacterium animalis subsp. lactis | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Mar 2027Efficacy and Safety of Thalidomide for Pediatric PFAPA Syndrome · Wenjie Zheng
Who these studies take
Of the 4 Hereditary Autoinflammatory Diseases studies recruiting now, 1 (25%) set no upper age limit and 0 (0%) stop at 75 or younger. 4 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (100%) | 4 (100%) |
| 18 | 4 (100%) | 4 (100%) |
| 30 | 4 (100%) | 4 (100%) |
| 40 | 4 (100%) | 4 (100%) |
| 50 | 4 (100%) | 4 (100%) |
| 65 | 4 (100%) | 4 (100%) |
| 75 | 4 (100%) | 4 (100%) |
| 85 | 4 (100%) | 4 (100%) |
Across all 12 studies, recruiting or not: 33% stop at 75 or younger and 33% at 65; 100% take children; 0% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 12 of 12. search them.
- Familial Mediterranean Fever and Related Disorders: Genetics and Disease CharacteristicsRecruitingNCT000013731 country
- Ilaris NIS in KoreaRecruitingNCT068381431 country
- Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil DisordersRecruitingNCT056563651 country
- Efficacy and Safety of Thalidomide for Pediatric PFAPA SyndromeNot yet recruitingNCT07476625Not applicable
- AutoInflammatory Disease Alliance Registry (AIDA)RecruitingNCT0520071522 countries
- Quality of Life in Patients With Auto-inflammatory DiseasesCompletedNCT03569644Not applicable1 country
- Immunome Project Consortium for Autoinflammatory DisordersCompletedNCT039191101 country
- Lanadelumab in FXII-associated Cold Autoinflammatory Syndrome (FACAS)Active, not recruitingNCT04278885Phase 21 country
- Homeopathic Treatment of Children Suffering From PFAPACompletedNCT059952881 country
- Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase DeficiencyTerminatedNCT002602991 country
- Ilaris (Canakinumab) in Patient With Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA)Status unknownNCT02775994Phase 11 country
- Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)WithdrawnNCT02535962Phase 2