Granulomatous Disease, Chronic: all 77 studies

Page 1 of 1. Open to participants first (17), then studies with results posted, then the rest; newest registration first within each.

• Open-label Gene Therapy Study in p47-CGDRecruitingNCT07826767Phase 1/2
• Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)RecruitingNCT07284641Phase 2
• Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous DiseaseEnrolling by invitationNCT07113743Phase 1/2
• Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous DiseaseRecruitingNCT06605378
• A Study of the Safety and Efficacy of Prime Editing (PM359) in Participants With p47phox Autosomal Recessive Chronic Granulomatous Disease (CGD )Enrolling by invitationNCT06559176Phase 1/2
• Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous DiseaseRecruitingNCT06325709Phase 1/2
• pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)Enrolling by invitationNCT06253507Phase 1/2
• Neutrophil Oxidative Burst in Early and Late Onset Pediatric Inflammatory Bowel DiseaseRecruitingNCT06162936
• Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) AntagonistsRecruitingNCT05463133Phase 1/2
• NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)RecruitingNCT05189925Phase 1
• Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RICRecruitingNCT04528355
• Lentiviral Gene Therapy for CGDNot yet recruitingNCT03645486Not applicable
• Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGDRecruitingNCT03055247Phase 2
• Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCTRecruitingNCT01962415Phase 2
• Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency DiseasesEnrolling by invitationNCT01852370Phase 1/2
• Evaluation of Patients With Immune Function AbnormalitiesRecruitingNCT00128973
• Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and GranulocytesRecruitingNCT00001405
• Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell TransplantationCompletedNCT03513328Phase 1/2Results posted
• Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerTerminatedNCT03333486Phase 2Results posted
• Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood CellsTerminatedNCT02512679Phase 2Results posted
• Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant CyclophosphamideTerminatedNCT02282904Phase 1/2Results posted
• Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)CompletedNCT01998633Phase 2Results posted
• Alefacept and Allogeneic Hematopoietic Stem Cell TransplantationTerminatedNCT01319851Not applicableResults posted
• Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous DiseaseTerminatedNCT01147042Phase 4Results posted
• Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous DiseaseCompletedNCT00578643Phase 2Results posted
• Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous DiseaseTerminatedNCT00325078Phase 1/2Results posted
• Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous DiseaseActive, not recruitingNCT06876363Phase 1/2
• Whole Blood Biospecimen Collection for Subjects With Chronic Granulomatous Disease (CGD)TerminatedNCT05915897
• Baby Detect : Genomic Newborn ScreeningCompletedNCT05687474
• Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)Active, not recruitingNCT05600907Early Phase 1
• Immunological Profile and Clinical Characteristics of Children Diagnosed With Chronic Granulomatous DiseaseStatus unknownNCT05546775
• Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory ComplicationsCompletedNCT05104723Phase 1/2
• IL-1 Receptor Inhibitor for Granulomatous Complications in Patients With Chronic Granulomatous DiseaseCompletedNCT04136028Early Phase 1
• Vitamin D3 For CGD Patients With BCGosis/ItisCompletedNCT03984890Phase 2/3
• Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous DiseaseCompletedNCT03983837Phase 2
• Skin Immunity Sample Collection Involving Blisters and BiopsiesWithdrawnNCT03921515Early Phase 1
• Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant CyclophosphamideActive, not recruitingNCT03910452Early Phase 1
• Early Check: Expanded Screening in NewbornsActive, not recruitingNCT03655223
• Role of Interferon-gamma 1-b (IFN-γ) on Cells of the Innate Immune System: Functional, Biochemical and Gene Expression Studies in Patients With Chronic Granulomatous DiseaseCompletedNCT03548818
• Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD PatientsStatus unknownNCT03547830Phase 2
• Natural History of Intestinal Inflammation in People With Primary Immune DysregulationsWithdrawnNCT03278912
• Pioglitazone Therapy for Chronic Granulomatous DiseaseTerminatedNCT03080480Phase 1/2
• Generation of Powerful Biological Tools for Understanding the Pathophysiology of Chronic Granulomatous Disease.TerminatedNCT02926963Not applicable
• Gene Therapy for X-linked Chronic Granulomatous DiseaseTerminatedNCT02757911Phase 1/2
• Effect of IFN-γ on Innate Immune CellsCompletedNCT02609932Phase 1
• Study of Gene Therapy Using a Lentiviral Vector to Treat X-linked Chronic Granulomatous DiseaseCompletedNCT02234934Phase 1/2
• Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous DiseaseCompletedNCT02233036
• Chronic Granulomatous Disease Study in ChinaStatus unknownNCT02231996
• Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995CompletedNCT02116764
• Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With CancerCompletedNCT02108028
• Patients Treated for Chronic Granulomatous Disease (CGD) Since 1995Status unknownNCT02082353
• Bone Marrow Transplant With Abatacept for Non-Malignant DiseasesCompletedNCT01917708Phase 1
• Gene Therapy for X-CGDStatus unknownNCT01906541Phase 1/2
• Gene Therapy for X-linked Chronic Granulomatous Disease (X-CGD)TerminatedNCT01855685Phase 1/2
• Radiofrequency Ablation for Liver Abscesses From Chronic Granulomatous DiseaseWithdrawnNCT01851460Phase 1
• Immune Disorder HSCT ProtocolActive, not recruitingNCT01821781Phase 2
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune DeficienciesActive, not recruitingNCT01652092Not applicable
• Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD)WithdrawnNCT01381003Phase 1/2
• Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Chronic Granulomatous Disease(CGD)Status unknownNCT01338675Phase 1/2
• Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune SystemCompletedNCT01063309
• Gene Therapy for X-linked Chronic Granulomatous Disease (CGD) in ChildrenCompletedNCT00927134Phase 1/2
• Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD)CompletedNCT00799071Phase 2
• Gene Therapy for Chronic Granulomatous Disease in KoreaWithdrawnNCT00778882Phase 1/2
• Gene Therapy for Chronic Granulomatous DiseaseStatus unknownNCT00564759Phase 1/2
• Gene Therapy for Chronic Granulomatous DiseaseTerminatedNCT00394316Early Phase 1
• Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung DiseaseCompletedNCT00368446
• Posaconazole to Treat Invasive Fungal InfectionsCompletedNCT00033982Phase 3
• Treatment of Chronic Granulomatous Disease With Allogeneic Stem Cell Transplantation Versus Standard of CareCompletedNCT00023192Phase 3
• Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited DisordersCompletedNCT00010361Not applicable
• Modified Stem Cell Transplantation Procedure for Treating Chronic Granulomatous DiseaseCompletedNCT00006417Phase 2
• Allogeneic Bone Marrow Transplantation in Patients With Primary ImmunodeficienciesTerminatedNCT00006054Not applicable
• Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related DisordersCompletedNCT00005933
• Stem Cell Transplant Following Low-Intensity Chemotherapy to Treat Chronic Granulomatous DiseaseCompletedNCT00001765Phase 1
• Diagnostic Effectiveness of Virtual BronchoscopyCompletedNCT00001515Phase 1
• Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-upCompletedNCT00001476Phase 1
• A Phase IV Study of Recombinant Human Gamma Interferon in Patients With Chronic Granulomatous Diseases of ChildhoodCompletedNCT00001317Phase 4
• Itraconazole for the Prevention of Fungal Infections in Chronic Granulomatous DiseaseCompletedNCT00001280Phase 2

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