Gram-Negative Bacterial Infections: all 58 studies

Page 1 of 1. Open to participants first (10), then studies with results posted, then the rest; newest registration first within each.

• Ceftazidime-Avibactam PK/PD and Resistance in Hematology PatientsNot yet recruitingNCT07703644
• The Effect of Adjunctive Melatonin With Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial InfectionsNot yet recruitingNCT07503600Phase 3
• Different Administration Regimens of CAZ-AVI in Combination With ATM for the Treatment of CR-GNBRecruitingNCT07478484Phase 4
• Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn InjuriesRecruitingNCT07465432Phase 4
• Immunogenicity and Safety of Meningococcal Conjugate Vaccine (EG-MCV4) in Healthy Adults Aged 19 to 55 Years OldRecruitingNCT07204457Phase 2/3
• A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)RecruitingNCT06462235Phase 2
• Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MVRecruitingNCT06135350Phase 2
• Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative InfectionsRecruitingNCT05639647Phase 2
• Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal InfectionRecruitingNCT04861922Phase 3
• Fosfomycin I.v. for Treatment of Severely Infected PatientsRecruitingNCT02979951
• Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell TransplantationTerminatedNCT04673175Phase 4Results posted
• A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric ParticipantsCompletedNCT04335539Phase 2Results posted
• Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants.TerminatedNCT04126031Phase 2Results posted
• Safety, Tolerability, Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)CompletedNCT03969901Phase 2/3Results posted
• Study of BPZE1 Intranasal Pertussis Vaccine (Administered Via VaxINator(TM)), Prime + Boost, in Healthy AdultsCompletedNCT03942406Phase 2Results posted
• A Pharmacokinetics Study of MK-7655A in Pediatric Participants With Gram-negative Infections (MK-7655A-020)CompletedNCT03230916Phase 1Results posted
• An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Without CRRTCompletedNCT02962934Results posted
• Shigella WRSS1 Vaccine Trial in BangladeshCompletedNCT02934178Phase 1Results posted
• Performance of Nucleic Acid Amplification Tests for the Detection of NG and CTCompletedNCT02870101Not applicableResults posted
• A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830TerminatedNCT02751424Phase 1Results posted
• Pharmacokinetic and Safety Study of Ceftolozane/Tazobactam in Pediatric Participants Receiving Antibiotic Therapy for Proven or Suspected Gram-negative Infection or for Peri-operative Prophylaxis (MK-7625A-010)CompletedNCT02266706Phase 1Results posted
• Safety Study of Live Attenuated Oral Shigella (WRSS1) Vaccine in Bangladeshi Adults and ChildrenCompletedNCT01813071Not applicableResults posted
• Consistency & Immunogenicity Study of 3 Lots of GSK's Hib Conjugate Vaccine Versus ActHIB & Pentacel in Healthy InfantsCompletedNCT01000974Phase 3Results posted
• Efficacy and Safety of Ceftaroline Versus Linezolid in Subjects With Complicated Skin and Skin Structure InfectionsCompletedNCT00633152Phase 2Results posted
• The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical TrialCompletedNCT00490477Phase 3Results posted
• A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick ExposureActive, not recruitingNCT07562087Phase 2
• Pharmacokinetics and Safety of HRS-8427 in Healthy Volunteers and in Patients With Impaired Renal FunctionCompletedNCT07070375Phase 1
• A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and InfantsCompletedNCT06086626Phase 2
• Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli InfectionsTerminatedNCT05210387Not applicable
• Quantifying Gram-negative Resistance to Empiric Therapy in the Intensive Care UnitCompletedNCT05171257
• The Clinical Character，Risk and Prognosis of Post-neurosurgical Intracranial Infection With Different Pathogens.Status unknownNCT04917380
• Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE InfectionsWithdrawnNCT04785924Phase 4
• A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric ParticipantsCompletedNCT04215991Phase 2
• Comparison of Solid Organ TransplantStatus unknownNCT04055922
• Understanding How Salmonella Typhi Infects Humans (Bottlenecks)CompletedNCT03889067Not applicable
• Effect of Different Colistin Doses on Clinical Outcome of Pediatric Cancer Patients With Gram Negative InfectionsCompletedNCT03397914Phase 4
• Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune SystemCompletedNCT03345992Phase 3
• A Study to Investigate the Intrapulmonary Lung Penetration of Nacubactam in Healthy ParticipantsCompletedNCT03182504Phase 1
• A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants Treated With Minocin® (Minocycline) for Infections Caused by Gram-negative Bacteria in a Real World SettingCompletedNCT03160040
• Feasibility Studies to Inform Novel Proposals to Avert Community-Based Antimicrobial Resistance SpreadStatus unknownNCT02666274
• Temocillin Pharmacokinetic in HemodialysisCompletedNCT02285075Phase 4
• Efficacy and Mortality of a Loading Dose of Colistin in Critical Ill PatientsStatus unknownNCT02117986Phase 4
• Survey of Severe Infections by Gram Negative Bacteria in Patients Submitted to Stem Cell TransplantCompletedNCT02088840
• Burden of Antibiotic Resistance in Gram-Negative Infections in Dutch HospitalsCompletedNCT02007343
• Multicentric Study About the Usefulness of Monitoring Plasma Levels of Colistin and Sodium Colistimethate in Patients With Infections Due to Multi-drug Resistant Gram Negative Bacilli, Treated With ColistinCompletedNCT01845246Not applicable
• Multicenter Open-label Randomized Controlled Trial (RCT) to Compare Colistin Alone Versus Colistin Plus MeropenemCompletedNCT01732250Phase 4
• Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Critically Ill PatientsStatus unknownNCT01600768Not applicable
• Safety, Pharmacokinetics (PK) and Tolerability Study of a Novel Drug for Treatment of Bacterial InfectionsCompletedNCT01015014Phase 1
• Impact of Imipenem With Amikacin Pharmacokinetic and PharmacodynamicCompletedNCT00950222Not applicable
• Early-Onset Sepsis Surveillance StudyCompletedNCT00874367
• Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected PatientsCompletedNCT00723502Phase 2
• Early Use of Polymyxin B Hemoperfusion in Abdominal SepsisCompletedNCT00629382Phase 4
• A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in AdultSuspendedNCT00563134Not applicable
• Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe SepsisCompletedNCT00406198Phase 4
• Surveillance Study - Incidence of Antibiotic Resistance in Serial Gram-negative Bloodstream IsolatesWithdrawnNCT00394784
• Gram Negative Bacteremia, Risk Factors for Failure of TherapyCompletedNCT00177957
• Piperacillin as a Part of Antibiotic Streamlining in the Intensive Care UnitCompletedNCT00177814
• Study Evaluating Tigecycline in Selected Serious Infections Due to Resistant Gram-Negative OrganismsCompletedNCT00079989Phase 3

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