Glioma: all 1,425 studies

Page 4 of 15. Open to participants first (355), then studies with results posted, then the rest; newest registration first within each.

• Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent GlioblastomaRecruitingNCT04977375Phase 1/2
• Study of GC101 TIL in Brain Glioma (Soochow2)RecruitingNCT04943913Early Phase 1
• rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMGRecruitingNCT04943848Phase 1
• The circTeloDIAG: Liquid Biopsy for Glioma TumorRecruitingNCT04931732
• A Living Tissue Bank of Patient-Derived Organoids From Glioma TumorsRecruitingNCT04865315
• A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid TumorsRecruitingNCT04794972Phase 1
• A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid TumorsRecruitingNCT04775485Phase 2
• Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating GliomasRecruitingNCT04772456Phase 1
• Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade GliomaRecruitingNCT04771806
• A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade GliomasNot yet recruitingNCT04745156Not applicable
• LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)RecruitingNCT04699773Not applicable
• A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK FusionRecruitingNCT04655404Early Phase 1
• A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)RecruitingNCT04573140Phase 1
• Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant GliomaRecruitingNCT04547777Phase 1
• Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade GliomaRecruitingNCT04543201Not applicable
• Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsRecruitingNCT04541082Phase 1
• Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade GliomaRecruitingNCT04540107Phase 1
• Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)RecruitingNCT04485559Phase 1
• MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated GliomasRecruitingNCT04373720Not applicable
• Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After SurgeryRecruitingNCT04316039Phase 2/3
• Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid TumorsRecruitingNCT04299191Phase 1/2
• Tessa Jowell BRAIN MATRIX - Platform StudyRecruitingNCT04274283
• Study of Recombinant Human Endostatin Combined with Temozolomide and Irinotecan in Recurrent GliomasRecruitingNCT04267978Phase 2
• Histopathology Images Based Prediction of Molecular Pathology in Glioma Using Artificial IntelligenceRecruitingNCT04217044
• MR Based Prediction of Molecular Pathology in Glioma Using Artificial IntelligenceRecruitingNCT04217018
• Prediction of Therapeutic Response of Apatinib in Recurrent GliomasRecruitingNCT04216550
• Survival Significance of Molecular Pathology and Genetic Variation in Brain GliomasRecruitingNCT04216537
• Histopathology Images Based Survival Prediction of Glioma Patients Using Artificial IntelligenceRecruitingNCT04215224
• MR Based Survival Prediction of Glioma Patients Using Artificial IntelligenceRecruitingNCT04215211
• Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System TumorsRecruitingNCT04185038Phase 1
• C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)RecruitingNCT04099797Phase 1
• A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 AlterationsRecruitingNCT04094610Phase 1/2
• Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System LesionsRecruitingNCT04047264Not applicable
• HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 1
• MSC-DNX-2401 in Treating Patients With Recurrent High-Grade GliomaRecruitingNCT03896568Phase 1
• Longitudinal Analysis of the Health-related Quality of Life in Glioma PatientsRecruitingNCT03849430
• Azoles Targeting Recurrent High Grade GliomasNot yet recruitingNCT03763396Early Phase 1
• Hyperpolarized Imaging in Diagnosing Participants With GliomaRecruitingNCT03739411Phase 1
• A Study Utilizing Escitalopram in Glioma PatientsRecruitingNCT03728673Phase 2
• Non-invasive Glioma Characterization Through Molecular ImagingRecruitingNCT03684109Not applicable
• Neuropsychological and Oncological Outcomes in Grade 2 or 3 Glioma Patients Undergoing Postoperative Modern RadiotherapyRecruitingNCT03534050Phase 2/3
• Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing SurgeryRecruitingNCT03510208Phase 1/2
• Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.RecruitingNCT03411408Not applicable
• Dabrafenib and/or Trametinib Rollover StudyRecruitingNCT03340506Phase 4
• Seizure Treatment in GliomaRecruitingNCT03048084Phase 4
• Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOARecruitingNCT02800486Phase 2
• Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients With Low Grade GliomasRecruitingNCT02686229
• Brain Glioma Registry Combining Clinical and Imaging InformationRecruitingNCT02619890
• Effect of Cytokine-induced Killer Cells for Advanced Malignant GliomasNot yet recruitingNCT02496988Phase 4
• Effect of Cytokine-induced Killer Cells for Stage I-II Malignant GliomasNot yet recruitingNCT02494804Phase 1/2
• Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)RecruitingNCT01906385Phase 1/2
• Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy ProgramRecruitingNCT01772771
• Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade GliomaRecruitingNCT01649830Phase 3
• Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem GliomaRecruitingNCT01106794
• Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid TumorsRecruitingNCT00870129Not applicable
• Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral MicrodialysisActive, not recruitingNCT05413304Phase 1Results posted
• PARP Inhibition for Gliomas (PI-4G or π4g)TerminatedNCT05297864Phase 2Results posted
• ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBMActive, not recruitingNCT05283109Phase 1Results posted
• Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 AlterationsTerminatedNCT05267106Phase 2Results posted
• Sophrology Treatment for Patients With Glial Tumours Requiring Speech TherapyTerminatedNCT05189366Not applicableResults posted
• Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)TerminatedNCT04804709Phase 1Results posted
• A Study of HMPL-306 in Advanced Solid Tumors With IDH MutationsTerminatedNCT04762602Phase 1Results posted
• Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas SystemCompletedNCT04743310Phase 2Results posted
• A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant CancerTerminatedNCT04730349Phase 1/2Results posted
• Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal EpilepsyTerminatedNCT04650204Phase 4Results posted
• A Phase II Trial of Poly-ICLC for Low-Grade GliomasTerminatedNCT04544007Phase 2Results posted
• Effect of Perampanel on Peritumoral Hyperexcitability in HGGCompletedNCT04497142Phase 1/2Results posted
• Infigratinib in Recurrent High-Grade Glioma PatientsTerminatedNCT04424966Early Phase 1Results posted
• Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04320888Phase 2Results posted
• INCB7839 in Treating Children With Recurrent/Progressive High-Grade GliomasCompletedNCT04295759Phase 1Results posted
• Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04284774Phase 2Results posted
• A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaCompletedNCT04238819Phase 1/2Results posted
• Neoadjuvant Chemoradiation for Resectable GlioblastomaTerminatedNCT04209790Phase 2Results posted
• Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT04195555Phase 2Results posted
• Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)Active, not recruitingNCT04164901Phase 3Results posted
• Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRICompletedNCT04097535Results posted
• Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant TumorsCompletedNCT04056910Phase 2Results posted
• BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 MutationsCompletedNCT03914742Phase 1/2Results posted
• Solriamfetol in Improving Sleep in Patients With Grade II-IV GliomaTerminatedNCT03868943Phase 2Results posted
• A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for ResectionCompletedNCT03834740Early Phase 1Results posted
• 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation TherapyCompletedNCT03778294Phase 2Results posted
• Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With GlioblastomaCompletedNCT03746080Phase 2Results posted
• Psychological Intervention for Caregivers of Patients With Malignant GliomasCompletedNCT03735498Not applicableResults posted
• Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator PhenotypeActive, not recruitingNCT03718767Phase 2Results posted
• Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03698994Phase 2Results posted
• REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent GliomaTerminatedNCT03690869Phase 1/2Results posted
• rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-severe Lymphopenic Gliomas Following Radiation and TemozolomideActive, not recruitingNCT03687957Phase 1/2Results posted
• A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 MutationCompletedNCT03684811Phase 1/2Results posted
• Trial of C134 in Patients With Recurrent GBMCompletedNCT03657576Phase 1Results posted
• Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent MedulloblastomaCompletedNCT03615404Phase 1Results posted
• Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS TumorsActive, not recruitingNCT03598244Phase 1Results posted
• Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 MutationsActive, not recruitingNCT03581292Phase 2Results posted
• MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine GliomaCompletedNCT03566199Phase 1/2Results posted
• Nivolumab for Recurrent or Progressive IDH Mutant GliomasCompletedNCT03557359Phase 2Results posted
• Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent GliomasCompletedNCT03532295Phase 2Results posted
• Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03526250Phase 2Results posted
• Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed GlioblastomaCompletedNCT03463265Phase 2Results posted
• Seizure Prophylaxis in Patients With Glioma or Brain MetastasisTerminatedNCT03436433Phase 2Results posted
• Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain TumorsCompletedNCT03387020Phase 1Results posted
• Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) AlterationsTerminatedNCT03352427Phase 2Results posted

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