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Fibrous Dysplasia, Polyostotic clinical trials

The registry lists 23 studies for Fibrous Dysplasia, Polyostotic across 7 countries. 5 are recruiting or about to start. 19 of them are mainly about Fibrous Dysplasia, Polyostotic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Completed
16
Recruiting
5
Withdrawn
1
Active, not recruiting
1

Phase

Phase 2
7
Phase 4
1
Phase 1
1
Phase 3
1

Where

United States
14
France
8
Italy
3
Germany
2
United Kingdom
2
Netherlands
1

Who runs them

National Institute of Dental and Craniofacial Research (NIDCR) (8) · Hospices Civils de Lyon (5) · AstraZeneca (2) · University Hospital, Clermont-Ferrand (1) · Boston Children's Hospital (1) · Children's Mercy Hospital Kansas City (1) · Yale University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1)

What is being tested here

Drugs under test in Fibrous Dysplasia, Polyostotic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Denosumab102
Burosumab001
Tocilizumab001
Fulvestrant001
Letrozole001
Alendronate001
Anastrozole001
Pegvisomant011

Drug classes tested here Aromatase inhibitors 3

Coming up

0phase 3 studies under way
1study finishes main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The study

Who these studies take

Of the 5 Fibrous Dysplasia, Polyostotic studies recruiting now, 3 (60%) set no upper age limit and 0 (0%) stop at 75 or younger. 3 (60%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 5
AgeWomenMen
103 (60%)3 (60%)
185 (100%)5 (100%)
305 (100%)5 (100%)
405 (100%)5 (100%)
505 (100%)5 (100%)
655 (100%)5 (100%)
755 (100%)5 (100%)
855 (100%)5 (100%)

Across all 23 studies, recruiting or not: 26% stop at 75 or younger and 26% at 65; 74% take children; 17% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 23 of 23. search them.