Dental Enamel Hypomineralization clinical trials
The registry lists 20 studies for Dental Enamel Hypomineralization across more than 10 countries. 6 are recruiting or about to start. 13 of them are mainly about Dental Enamel Hypomineralization (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its 2 narrower conditions too, such as Molar Hypomineralization: 169 studies, 54 open.
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Who runs them
Cairo University (5) · Pamukkale University (1) · University of Pavia (1) · Beni-Suef University (1) · King Abdulaziz University (1) · University of Bergen (1) · Afyonkarahisar Health Sciences University (1) · Shaimaa Abdelrahman (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Apr 2027Zirconia and Bioflx Crowns for Primary Anterior Teeth · Hue University of Medicine and Pharmacy
- Jun 2027Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth · Foundation University Islamabad
- Jun 2027Esthetic Impact of Different Minimally Invasive Approaches on Hypomineralized Permanent Anterior Teeth · Shaimaa Abdelrahman
Who these studies take
Of the 3 Dental Enamel Hypomineralization studies recruiting now, 0 (0%) set no upper age limit and 3 (100%) stop at 75 or younger. 3 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (100%) | 3 (100%) |
| 18 | 2 (67%) | 2 (67%) |
| 30 | 0 (0%) | 0 (0%) |
| 40 | 0 (0%) | 0 (0%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 20 studies, recruiting or not: 95% stop at 75 or younger and 95% at 65; 100% take children; 0% are for women only and 0% for men only; 55% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 20 of 20. search them.
- Esthetic Impact of Different Minimally Invasive Approaches on Hypomineralized Permanent Anterior TeethNot yet recruitingNCT07906236Not applicable1 country
- Clinical Performance of Orthodontic Bands in the Restorative Treatment of Hypomineralised Primary Second MolarsRecruitingNCT07814716Not applicable1 country
- Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior TeethRecruitingNCT073300891 country
- Hydroxyapatite Toothpastes and Enamel Remineralization:RecruitingNCT07069218Not applicable1 country
- Prevalence of Hypomineralized Second Primary Molars and Its Association with Molar-Incisor Hypomineralization.Not yet recruitingNCT06727539
- Prevalence of Hypomineralized Second Primary Molars In A Group of Egyptian ChildrenNot yet recruitingNCT06736535
- Zirconia and Bioflx Crowns for Primary Anterior TeethActive, not recruitingNCT07691905Not applicable1 country
- Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization OpacitiesCompletedNCT07494682Not applicable1 country
- Clinical Success of Stainless Steel Crowns Applied Using Different CementsActive, not recruitingNCT06318520Not applicable1 country
- Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory SettingActive, not recruitingNCT06696105Phase 41 country
- Analysis of Treatment Outcomes in Patients Affected by Molar-Incisor Hypomineralization (MIH)Active, not recruitingNCT06228989Not applicable
- Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric PatientsCompletedNCT04710927Not applicable1 country
- The Effectiveness of Biomimetic Materials in Preventing Enamel Demineralization During Fixed Orthodontic TreatmentActive, not recruitingNCT05940701Not applicable1 country
- Esthetic Management of Anterior Teeth Utilizing Two Micro Abrasion TreatmentsCompletedNCT05900817Not applicable1 country
- ART Compared to the Hall Technique for Management HSPMStatus unknownNCT05816096Not applicable1 country
- The Association Between MIH and HSPMCompletedNCT043443401 country
- Hypo-mineralization of Primary and Permanent Teeth in a Group of Children With Stunted Growth.A Cross Sectional Study.Status unknownNCT047746531 country
- PMCs as a Treatment of Children With HSPM Using the HTStatus unknownNCT04265183Not applicable1 country
- Oral Health Intervention Program for Children With Congenital Heart DefectsCompletedNCT03311438Not applicable
- Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic TreatmentStatus unknownNCT03187548Phase 1