Corticobasal Degeneration clinical trials
The registry lists 64 studies for Corticobasal Degeneration across more than 10 countries. 26 are recruiting or about to start. 11 of them are mainly about Corticobasal Degeneration (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Status
Who runs them
University of California, San Francisco (6) · University of California, Los Angeles (2) · BioSensics (2) · University of Colorado, Denver (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · Skane University Hospital (2) · University of Pennsylvania (2) · Massachusetts General Hospital (2)
What is being tested here
Drugs under test in Corticobasal Degeneration studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| NIO752 | 1 | 0 | 1 |
| Nicotinamide-beta-riboside | 1 | 0 | 1 |
| Glycerol phenylbutyrate | 0 | 0 | 1 |
| Lithium | 0 | 0 | 1 |
| Pimavanserin | 0 | 1 | 1 |
| Flortaucipir | 0 | 0 | 1 |
| TPI-287 | 0 | 0 | 1 |
| Davunetide | 0 | 0 | 1 |
| Fasudil | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Nov 2026Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling · University Health Network, Toronto
- Dec 2026Diagnosing Frontotemporal Lobar Degeneration · University Health Network, Toronto
- Dec 2026AI-Enhanced Optimization of Acute Levodopa Challenge Test · Beijing Tiantan Hospital
- Feb 2027Scrambler Therapy for Corticobasal Syndrome-Associated Pain · Johns Hopkins University
- Jun 2027Music and Brain Stimulation for Upper Extremity Performance in Patients With Corticobasal Syndrome · Johns Hopkins University
- Jul 2027Gait Analysis in Neurological Disease · Beth Israel Deaconess Medical Center
- Oct 2027Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia · National Institute of Neurological Disorders and Stroke (NINDS)
Who these studies take
Of the 21 Corticobasal Degeneration studies recruiting now, 12 (57%) set no upper age limit and 1 (5%) stop at 75 or younger. 3 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (14%) | 3 (14%) |
| 18 | 12 (57%) | 12 (57%) |
| 30 | 17 (81%) | 17 (81%) |
| 40 | 19 (90%) | 19 (90%) |
| 50 | 21 (100%) | 21 (100%) |
| 65 | 21 (100%) | 21 (100%) |
| 75 | 21 (100%) | 21 (100%) |
| 85 | 20 (95%) | 20 (95%) |
Across all 64 studies, recruiting or not: 2% stop at 75 or younger and 0% at 65; 6% take children; 0% are for women only and 0% for men only; 34% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 64. Browse all 64 → or search them.
- Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal DementiaRecruitingNCT032251441 country
- A Wearable Sensor Platform for Remote Monitoring of Individuals on the Frontotemporal Dementia SpectrumNot yet recruitingNCT075693671 country
- A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of NIO752 in Primary TauopathiesNot yet recruitingNCT07868328Phase 2
- ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)RecruitingNCT043636842 countries
- Wellness in PSP and CBDRecruitingNCT07844655Not applicable1 country
- Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH)RecruitingNCT078059671 country
- Neurodegenerative Diseases Progression Markers (MARKERS-NDD)RecruitingNCT065967461 country
- Imaging Studies in Corticobasal SyndromeRecruitingNCT070008511 country
- Digital Measurements of Motor and Voice Functions in FTDNot yet recruitingNCT07333898
- The Swedish BioFINDER 2 StudyRecruitingNCT03174938Not applicable1 country
- Research Study for Patients With Neurological Diseases Which Evaluates the Patient Experience of the MemorEM DeviceEnrolling by invitationNCT07222605Not applicable1 country
- UPenn Observational Research Repository on Neurodegenerative DiseaseRecruitingNCT047153991 country
- The CurePSP Genetics ProgramRecruitingNCT066476411 country
- Scrambler Therapy for Corticobasal Syndrome-Associated PainRecruitingNCT05653778Not applicable1 country
- Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183ARecruitingNCT06932809Early Phase 11 country
- tDCS as Treatment for Motor FunctionRecruitingNCT07291687Not applicable1 country
- Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative ModelingRecruitingNCT065297441 country
- STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care PartnersRecruitingNCT06613204Not applicable1 country
- Pilot Trial Evaluating Patient Experience With the MemorEM for Patients With Neurological DiseasesEnrolling by invitationNCT07049341Not applicable1 country
- AI-Enhanced Optimization of Acute Levodopa Challenge TestRecruitingNCT069498651 country
- Diagnosing Frontotemporal Lobar DegenerationRecruitingNCT029646371 country
- NYSCF Scientific Discovery BiobankRecruitingNCT062031061 country
- The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical ParkinsonismRecruitingNCT06162013Phase 21 country
- The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related DisordersRecruitingNCT06174948Not applicable1 country
- Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian SyndromesRecruitingNCT066456261 country
- Modifiable Variables in Parkinsonism (MVP)RecruitingNCT021948161 country
- Community Outreach for Palliative Engagement -- Parkinson DiseaseActive, not recruitingNCT05222386Not applicable1 country
- PROFIL Study to Investigate the Effect of GPB on NfL Levels in Patients With Corticobasal Syndrome (CBS)CompletedNCT05983588Phase 21 country
- Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register StudyActive, not recruitingNCT062095151 country
- Gait Analysis in Neurological DiseaseActive, not recruitingNCT029947191 country
- Music and Brain Stimulation for Upper Extremity Performance in Patients With Corticobasal SyndromeActive, not recruitingNCT05073471Not applicable1 country
- Neurological Soft Signs in Neurodegenerative DementiasCompletedNCT063549331 country
- A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) SyndromesActive, not recruitingNCT059568341 country
- Proactive and Integrated Management and Empowerment in Parkinson's Disease (PRIME-UK): A New Model of Care (PRIME-RCT)CompletedNCT05127057Not applicable1 country
- Neuroinflammation in FTLDActive, not recruitingNCT068708381 country
- Activity of Cerebral Networks, Amyloid and Microglia in Aging and Alzheimer's DiseaseCompletedNCT06224920
- Misfolded Proteins in the Skin of People With Parkinson's Disease and Other ParkinsonismCompletedNCT045180591 country
- 4 Repeat Tauopathy Neuroimaging InitiativeCompletedNCT018044521 country
- Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural NetworksCompletedNCT031533711 country
- 4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2CompletedNCT029661452 countries
- ADDIA Proof-of-Performance Clinical StudyCompletedNCT030305865 countries
- A Pilot Trial of Lithium in Subjects With Progressive Supranuclear Palsy or Corticobasal DegenerationCompletedNCT00703677Phase 1/22 countries
- In-Home Care for Patients With PSP and Related DisordersCompletedNCT03552484Not applicable1 country
- Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian DisordersStatus unknownNCT05638477Not applicable1 country
- tDCS and Speech Therapy for Motor Speech Disorders Caused by FTLD Syndromes: a Feasibility StudyWithdrawnNCT04883229Not applicable
- Rho Kinase (ROCK) Inhibitor in Tauopathies - 1Status unknownNCT04734379Phase 21 country
- Complex Eye Movements in Parkinson's Disease and Related Movement DisordersCompletedNCT049256221 country
- Human CNS Tau Kinetics in TauopathiesCompletedNCT035451261 country
- Optimization of Morphomer-based Alpha-synuclein PET TracersCompletedNCT050671921 country
- Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders (PD), Essential Tremor (ET), Cortical Basal Degeneration (CBD), Multiple Systems Atrophy (MSA), Magnetoencephalography.CompletedNCT021320521 country