Compartment Syndromes clinical trials
The registry lists 52 studies for Compartment Syndromes across more than 10 countries. 8 are recruiting or about to start. 43 of them are mainly about Compartment Syndromes (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02. Counting its narrower condition Intra-Abdominal Hypertension too: 120 studies, 22 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
J&M Shuler (5) · Compremium AG (3) · Twin Star Medical, Inc. (2) · Emory University (2) · MY01 Inc. (2) · University of Wisconsin, Madison (2) · Medical University Innsbruck (1) · University of Missouri-Columbia (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Nov 2026Can Near-Infrared Spectroscopy (NIRS) or Intramuscular Glucose Levels Detect Impaired Leg Compartment' Perfusion? · University of Florida
- Dec 2026Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients · Johns Hopkins University
- Aug 2027Physiotherapy or Fasciotomy as Treatment for Chronic Exertional Compartment Syndrome in the Lower Leg? · Bispebjerg Hospital
Who these studies take
Of the 5 Compartment Syndromes studies recruiting now, 3 (60%) set no upper age limit and 2 (40%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 4 (80%) | 4 (80%) |
| 75 | 4 (80%) | 4 (80%) |
| 85 | 3 (60%) | 3 (60%) |
Across all 52 studies, recruiting or not: 38% stop at 75 or younger and 33% at 65; 25% take children; 0% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- From Blast Injury to Multicompartment Dysfunction:Nov 2, 2026NCT07911085
Studies
Recruiting first, then most recently updated. Showing 50 of 52. Browse all 52 → or search them.
- From Blast Injury to Multicompartment Dysfunction:Not yet recruitingNCT079110851 country
- Physiotherapy or Fasciotomy as Treatment for Chronic Exertional Compartment Syndrome in the Lower Leg?RecruitingNCT03584815Not applicable1 country
- Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO PatientsRecruitingNCT05830721Not applicable1 country
- Can Near-Infrared Spectroscopy (NIRS) or Intramuscular Glucose Levels Detect Impaired Leg Compartment' Perfusion?RecruitingNCT065128701 country
- Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.Not yet recruitingNCT066726011 country
- Real-time Soft Tissue Assessment Using a Technologically Advanced pH Monitoring SystemNot yet recruitingNCT04725604Not applicable1 country
- Chemical Analysis of Limb MicrofluidicsRecruitingNCT060504991 country
- The Research About the ACS After Femoropopliteal Arterial InjuriesRecruitingNCT050302591 country
- BM-MNCs for Lower Extremity Compartment Syndrome InjuryActive, not recruitingNCT03880656Phase 11 country
- The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb HaemodynamicsCompletedNCT060366411 country
- Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin ACompletedNCT05466539Phase 41 country
- NIRST and ICG-based Perfusion Imaging in Acute Compartment SyndromeCompletedNCT056723811 country
- Our Emergency Fasciotomy and Amputation ExperiencesCompletedNCT067644461 country
- ACS Monitoring Charité BerlinCompletedNCT06030635Not applicable1 country
- Botox for the Treatment of Recurrent Chronic Exertional Compartment SyndromeTerminatedNCT05006417Phase 41 country
- Clinical Application and Validation of Innovative TourniquetCompletedNCT05605990Not applicable1 country
- MY01 - An Aid for Diagnosing Acute Compartment Syndrome in Real TimeCompletedNCT04016103Not applicable1 country
- Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment SyndromeCompletedNCT04012723Not applicable1 country
- Long Term Outcomes of Pediatric Compartment SyndromeCompletedNCT035403941 country
- Evaluation of Acute Lower Limb IschemiaCompletedNCT0513867910 countries
- COmpartment Syndrome vaLidation Of Non Invasive Assessment of Tissue PressureCompletedNCT03840434Not applicable1 country
- Botox for the Treatment of Chronic Exertional Compartment SyndromeTerminatedNCT03922139Phase 1/21 country
- Non-invasive Limb Compartment Pressure MeasurementCompletedNCT03730688Not applicable1 country
- SWISS_CLEARANCE - Compartment Compressibility Monitoring Using CPM#1CompletedNCT05483946Not applicable1 country
- Near Infrared Spectroscopy in Patients Undergoing Robotic Assisted Laparoscopic Surgery in the Trendelenburg PositionTerminatedNCT028292421 country
- SWISS_EVIDENCE - Compartment Compressibility Monitoring Using CPM#1CompletedNCT05367921Not applicable1 country
- Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment SyndromeStatus unknownNCT04671173Not applicable1 country
- Diagnostic Value of Compression Ultrasound to Detect Acute Compartment Syndrome After Lower Limb RevascularisationStatus unknownNCT04806555Not applicable1 country
- Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy VolunteersCompletedNCT04113954Phase 11 country
- Evaluating the Diagnostic Performance of ACS Using NIRS in Traumatized Lower ExtremitiesStatus unknownNCT036040291 country
- Early Diagnosis of Compartment Syndrome by Multimodal Detection TechniqueCompletedNCT04442672Not applicable1 country
- Natural History of Anterior Compartment Pressures of the Thigh Following Femur FractureTerminatedNCT00919464Not applicable
- Musculoskeletal Non-tumoral Pathology Quantitative PerfusionStatus unknownNCT02683252Not applicable1 country
- Ability of Near Infrared Spectroscopy to Isolate Compartments of the ExtremityCompletedNCT012834511 country
- Predicting Acute Compartment Syndrome (PACS)CompletedNCT01561261Not applicable1 country
- Use of Near Infrared Spectroscopy to Detect Muscle Perfusion in the Lower Extremity of Uninjured SubjectsCompletedNCT012840231 country
- Hyperbaric Oxygen Therapy RegistryStatus unknownNCT02483650
- Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue ExpanderTerminatedNCT01171534Not applicable1 country
- Effects of Perioperative Patient Education Regarding Compartment Syndrome on Post-operative Opioid ConsumptionStatus unknownNCT03359031Not applicable1 country
- Phase I, Arteriocyte Magellan MAR01 Therapy - Compartment Syndrome and Battlefield TraumaCompletedNCT01837264Phase 11 country
- Study to Determine the Utility of Wound Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing ChangesTerminatedNCT00121537Not applicable1 country
- Assessment of Near Infrared Spectroscopy as a Diagnostic Tool in Acute Compartment SyndromeCompletedNCT010779341 country
- Muscle Oxygenation and Skin PigmentationWithdrawnNCT00747162Phase 41 country
- Double Blinded, Randomized Clinical Trial of the Twin Star ECSPRESS Monitoring System for the Reduction of the Incidence of FasciotomyStatus unknownNCT01879696Not applicable1 country
- The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment SyndromeCompletedNCT009212711 country
- The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment SyndromeStatus unknownNCT011716381 country
- The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome in Injured SoldiersCompletedNCT011237981 country
- Percutaneous Catheter Decompression in the Treatment of Elevated Intra-abdominal PressureCompletedNCT01230255Phase 31 country
- Continuous Pressure Monitoring In Lower Leg FracturesTerminatedNCT00358514Not applicable1 country
- Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured LegStatus unknownNCT00681616Not applicable1 country