Compartment Syndromes clinical trials
The registry lists 52 studies for Compartment Syndromes across more than 10 countries. 8 are recruiting or about to start. 43 of them are mainly about Compartment Syndromes (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02. Counting its narrower condition Intra-Abdominal Hypertension too: 120 studies, 22 open.
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Who runs them
J&M Shuler (5) · Compremium AG (3) · University of Wisconsin, Madison (2) · Twin Star Medical, Inc. (2) · Emory University (2) · MY01 Inc. (2) · Johns Hopkins University (1) · Orlando Regional Medical Center (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Nov 2026Can Near-Infrared Spectroscopy (NIRS) or Intramuscular Glucose Levels Detect Impaired Leg Compartment' Perfusion? · University of Florida
- Dec 2026Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients · Johns Hopkins University
- Aug 2027Physiotherapy or Fasciotomy as Treatment for Chronic Exertional Compartment Syndrome in the Lower Leg? · Bispebjerg Hospital
Who these studies take
Of the 5 Compartment Syndromes studies recruiting now, 3 (60%) set no upper age limit and 2 (40%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 4 (80%) | 4 (80%) |
| 75 | 4 (80%) | 4 (80%) |
| 85 | 3 (60%) | 3 (60%) |
Across all 52 studies, recruiting or not: 38% stop at 75 or younger and 33% at 65; 25% take children; 0% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- From Blast Injury to Multicompartment Dysfunction:Nov 2, 2026NCT07911085
Studies
Recruiting first, then most recently updated. Showing 50 of 52. Browse all 52 → or search them.
- From Blast Injury to Multicompartment Dysfunction:Not yet recruitingNCT079110851 country
- Physiotherapy or Fasciotomy as Treatment for Chronic Exertional Compartment Syndrome in the Lower Leg?RecruitingNCT03584815Not applicable1 country
- Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO PatientsRecruitingNCT05830721Not applicable1 country
- Can Near-Infrared Spectroscopy (NIRS) or Intramuscular Glucose Levels Detect Impaired Leg Compartment' Perfusion?RecruitingNCT065128701 country
- Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.Not yet recruitingNCT066726011 country
- Real-time Soft Tissue Assessment Using a Technologically Advanced pH Monitoring SystemNot yet recruitingNCT04725604Not applicable1 country
- Chemical Analysis of Limb MicrofluidicsRecruitingNCT060504991 country
- The Research About the ACS After Femoropopliteal Arterial InjuriesRecruitingNCT050302591 country
- BM-MNCs for Lower Extremity Compartment Syndrome InjuryActive, not recruitingNCT03880656Phase 11 country
- The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb HaemodynamicsCompletedNCT060366411 country
- Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin ACompletedNCT05466539Phase 41 country
- NIRST and ICG-based Perfusion Imaging in Acute Compartment SyndromeCompletedNCT056723811 country
- Our Emergency Fasciotomy and Amputation ExperiencesCompletedNCT067644461 country
- ACS Monitoring Charité BerlinCompletedNCT06030635Not applicable1 country
- Botox for the Treatment of Recurrent Chronic Exertional Compartment SyndromeTerminatedNCT05006417Phase 41 country
- Clinical Application and Validation of Innovative TourniquetCompletedNCT05605990Not applicable1 country
- MY01 - An Aid for Diagnosing Acute Compartment Syndrome in Real TimeCompletedNCT04016103Not applicable1 country
- Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment SyndromeCompletedNCT04012723Not applicable1 country
- Long Term Outcomes of Pediatric Compartment SyndromeCompletedNCT035403941 country
- Evaluation of Acute Lower Limb IschemiaCompletedNCT0513867910 countries
- COmpartment Syndrome vaLidation Of Non Invasive Assessment of Tissue PressureCompletedNCT03840434Not applicable1 country
- Botox for the Treatment of Chronic Exertional Compartment SyndromeTerminatedNCT03922139Phase 1/21 country
- Non-invasive Limb Compartment Pressure MeasurementCompletedNCT03730688Not applicable1 country
- SWISS_CLEARANCE - Compartment Compressibility Monitoring Using CPM#1CompletedNCT05483946Not applicable1 country
- Near Infrared Spectroscopy in Patients Undergoing Robotic Assisted Laparoscopic Surgery in the Trendelenburg PositionTerminatedNCT028292421 country
- SWISS_EVIDENCE - Compartment Compressibility Monitoring Using CPM#1CompletedNCT05367921Not applicable1 country
- Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment SyndromeStatus unknownNCT04671173Not applicable1 country
- Diagnostic Value of Compression Ultrasound to Detect Acute Compartment Syndrome After Lower Limb RevascularisationStatus unknownNCT04806555Not applicable1 country
- Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy VolunteersCompletedNCT04113954Phase 11 country
- Evaluating the Diagnostic Performance of ACS Using NIRS in Traumatized Lower ExtremitiesStatus unknownNCT036040291 country
- Early Diagnosis of Compartment Syndrome by Multimodal Detection TechniqueCompletedNCT04442672Not applicable1 country
- Natural History of Anterior Compartment Pressures of the Thigh Following Femur FractureTerminatedNCT00919464Not applicable
- Musculoskeletal Non-tumoral Pathology Quantitative PerfusionStatus unknownNCT02683252Not applicable1 country
- Ability of Near Infrared Spectroscopy to Isolate Compartments of the ExtremityCompletedNCT012834511 country
- Predicting Acute Compartment Syndrome (PACS)CompletedNCT01561261Not applicable1 country
- Use of Near Infrared Spectroscopy to Detect Muscle Perfusion in the Lower Extremity of Uninjured SubjectsCompletedNCT012840231 country
- Hyperbaric Oxygen Therapy RegistryStatus unknownNCT02483650
- Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue ExpanderTerminatedNCT01171534Not applicable1 country
- Effects of Perioperative Patient Education Regarding Compartment Syndrome on Post-operative Opioid ConsumptionStatus unknownNCT03359031Not applicable1 country
- Phase I, Arteriocyte Magellan MAR01 Therapy - Compartment Syndrome and Battlefield TraumaCompletedNCT01837264Phase 11 country
- Study to Determine the Utility of Wound Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing ChangesTerminatedNCT00121537Not applicable1 country
- Assessment of Near Infrared Spectroscopy as a Diagnostic Tool in Acute Compartment SyndromeCompletedNCT010779341 country
- Muscle Oxygenation and Skin PigmentationWithdrawnNCT00747162Phase 41 country
- Double Blinded, Randomized Clinical Trial of the Twin Star ECSPRESS Monitoring System for the Reduction of the Incidence of FasciotomyStatus unknownNCT01879696Not applicable1 country
- The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment SyndromeCompletedNCT009212711 country
- The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment SyndromeStatus unknownNCT011716381 country
- The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome in Injured SoldiersCompletedNCT011237981 country
- Percutaneous Catheter Decompression in the Treatment of Elevated Intra-abdominal PressureCompletedNCT01230255Phase 31 country
- Continuous Pressure Monitoring In Lower Leg FracturesTerminatedNCT00358514Not applicable1 country
- Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured LegStatus unknownNCT00681616Not applicable1 country