Chikungunya Fever clinical trials
The registry lists 88 studies for Chikungunya Fever across more than 10 countries. 21 are recruiting or about to start. 54 of them are mainly about Chikungunya Fever (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-16.
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Who runs them
Valneva Austria GmbH (11) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · Bavarian Nordic (7) · Centre Hospitalier Universitaire de la Réunion (6) · Themis Bioscience GmbH (4) · Institut Pasteur (3) · Bharat Biotech International Limited (2) · University of Notre Dame (2)
What is being tested here
Drugs under test in Chikungunya Fever studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Chikungunya vaccine | 1 | 4 | 7 |
| Measles-Mumps-Rubella Vaccine | 0 | 0 | 1 |
| Chloroquine | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5, phase 3 first
- Jul 2027Trial to Evaluate the Immunogenicity and Safety of the Co-administration of Live Attenuated Dengue and Chikungunya Vaccines Compared to Separate Administration in Adults Aged 18 to 59 Years. · Phase 3 · Butantan Institute
- Feb 2027Chikungunya Virus Detection in Semen · University Hospital, Toulouse
- Jun 2027Real-world Effectiveness, Safety & Immunogenicity of Chikungunya Vaccination: Ambispective Study in Reunion & French Guiana · Centre Hospitalier Universitaire de la Réunion
- Jul 2027Effects Of A Rehabilitation Protocol On Muscle Strength, Muscle Fatigue And Postural Control In Post-Dengue And Chikungunya Patients · Universidade do Estado do Pará
- Jul 2027Smart Analysis and Decision-Making for Emerging Infectious Diseases · Peking University
Who these studies take
Of the 8 Chikungunya Fever studies recruiting now, 5 (63%) set no upper age limit and 3 (38%) stop at 75 or younger. 6 (75%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (38%) | 3 (38%) |
| 18 | 7 (88%) | 7 (88%) |
| 30 | 7 (88%) | 7 (88%) |
| 40 | 7 (88%) | 7 (88%) |
| 50 | 7 (88%) | 7 (88%) |
| 65 | 7 (88%) | 7 (88%) |
| 75 | 6 (75%) | 6 (75%) |
| 85 | 5 (63%) | 5 (63%) |
Across all 88 studies, recruiting or not: 55% stop at 75 or younger and 48% at 65; 40% take children; 2% are for women only and 1% for men only; 59% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Chikungunya Fever studies take
Of 14 interventional studies with no phase under Chikungunya Fever, half reached primary completion within 20 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 20 mo5–41 · 14 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 88. Browse all 88 → or search them.
- Evaluation of IXCHIQ® Vaccine ImmunogenicityNot yet recruitingNCT07846293Phase 21 country
- Real-world Effectiveness, Safety & Immunogenicity of Chikungunya Vaccination: Ambispective Study in Reunion & French GuianaRecruitingNCT06928753Phase 42 countries
- Against Chikungunya Virus and Neonatal InfectionRecruitingNCT07190560Not applicable3 countries
- Smart Analysis and Decision-Making for Emerging Infectious DiseasesEnrolling by invitationNCT07678619Not applicable1 country
- VLA1553-403 Pregnancy Surveillance StudyEnrolling by invitationNCT074145241 country
- Observational Study to Assess the Effectiveness of VLA1553 Vaccine in Preventing Chikungunya During a Pilot Vaccination Strategy in BrazilEnrolling by invitationNCT073470021 country
- Trial to Evaluate the Immunogenicity and Safety of the Co-administration of Live Attenuated Dengue and Chikungunya Vaccines Compared to Separate Administration in Adults Aged 18 to 59 Years.Not yet recruitingNCT06973772Phase 31 country
- An Efficacy, Safety, and Immunogenicity Study of CHIKV VLP Vaccine for the Prevention of Chikungunya Disease in Adolescents and AdultsRecruitingNCT07467707Phase 32 countries
- Effects Of A Rehabilitation Protocol On Muscle Strength, Muscle Fatigue And Postural Control In Post-Dengue And Chikungunya PatientsNot yet recruitingNCT07600879Not applicable1 country
- A Phase I Study of PepGNP-ChikV in Healthy VolunteersNot yet recruitingNCT07394426Early Phase 1
- A Seamless Phase II/III, Observer-blind, to Evaluate Immunogenicity and Safety of Chikungunya Virus Vaccine in Healthy Subjects 12-65Years of Age.RecruitingNCT07555392Phase 2/31 country
- Xpert® Tropical Fever Test on GeneXpert® Edge X SystemEnrolling by invitationNCT075202791 country
- Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health PerspectiveRecruitingNCT073589101 country
- A Clinical Study on the Efficacy and Safety of Reduning Injection in the Treatment of Chikungunya FeverNot yet recruitingNCT07126171Not applicable1 country
- Real-World Study on Chinese Medicine for Treating Chikungunya FeverRecruitingNCT071207241 country
- Prospective Clinical Registry for Evaluation of Exanthematous Infections and CoinfectionsNot yet recruitingNCT07112846
- Chikungunya Virus Detection in SemenNot yet recruitingNCT06983548Not applicable1 country
- Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne DiseasesNot yet recruitingNCT06859619Not applicable1 country
- Virological and Immunological Determinants of Arbovirus Infection in New CaledoniaRecruitingNCT04619823Not applicable1 country
- Genetic Evolution of Arboviruses in New Caledonia Between 1995 and 2024 and Impact of WolbachiaRecruitingNCT046153641 country
- Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and MalariaNot yet recruitingNCT046725771 country
- Investigating Vector-Borne Determinants of Aedes Transmitted Arboviral Infections in Cambodia: An Observational Longitudinal Cohort Study in ChildrenCompletedNCT035342451 country
- A Safety and Immunogenicity Study of CHIKV VLP Vaccine in Children.Active, not recruitingNCT07003984Phase 33 countries
- A Phase 2 Clinical Trial of VLA1553 in Healthy Children Aged 1 to 11 YearsCompletedNCT06106581Phase 22 countries
- Long-term Follow-up Study to Evaluate Safety and Immunogenicity of CHIKV VLP Single or Booster VaccinationActive, not recruitingNCT06007183Phase 31 country
- Prospective Safety Cohort Study After VLA1553 Vaccination in Municipalities Selected for Participation in the VLA1553 Pilot Vaccination Strategy in BrazilActive, not recruitingNCT072547021 country
- Antibody Persistence And Long Term Safety Of A Chikungunya Virus Vaccine (VLA1553)Active, not recruitingNCT04838444Phase 31 country
- A Multicenter Study to Evaluate Safety and Immunogenicity of a Live-attenuated Chikungunya Vaccine in AdolescentsCompletedNCT04650399Phase 31 country
- Using Digital Technology for the Prevention of Aedes-Borne Diseases in Colombian CommunitiesCompletedNCT07517731Not applicable2 countries
- Trial of an Inactivated Chikungunya Virus VaccineCompletedNCT06669208Phase 11 country
- Testing Combined IIT-SIT to Control Mosquito-Borne Diseases At ScaleTerminatedNCT06595745Not applicable1 country
- Post-Chikungunya Rheumatism - Rheumatology Follow-up of Patients After 15 YearsCompletedNCT048385741 country
- Assessment of Chikungunya Virus Seroprevalence Before VLA1553 Vaccination in the Municipalities Selected for Participation in the VLA1553 Pilot Vaccination Strategy in BrazilActive, not recruitingNCT071638451 country
- Phase 1 Study of SAR440894 vs PlaceboCompletedNCT04441905Phase 11 country
- A Trial to Evaluate the Safety and Immunogenicity of VLA1553 in Healthy ChildrenWithdrawnNCT07133178Phase 3
- A Cluster-randomized Trial to EValuate the Efficacy of Wolbachia-InfecTed Aedes Aegypti Mosquitoes in Reducing the Incidence of Arboviral Infection in Brazil (EVITA Dengue)CompletedNCT04514107Not applicable1 country
- Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne DiseasesCompletedNCT04343521Not applicable1 country
- Spatial Repellents for Aedes-borne Virus Control in Sri LankaCompletedNCT05452447Not applicable1 country
- The Interest of Systematic Screening for Dengue, Chikungunya, and Zika, in Malaria-negative Return TravelersActive, not recruitingNCT066513721 country
- Seamless Controlled Trial To Evaluate Safety And Immunogenicity of Chikungunya Vaccine in LatinAmerica and AsiaTerminatedNCT04566484Phase 2/35 countries
- Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West AfricaCompletedNCT06257810Not applicable2 countries
- Safety and Immunogenicity of CHIKV VLP Vaccine PXVX0317 in Adults ≥65 YearsCompletedNCT05349617Phase 31 country
- A Clinical Phase 3 Trial of VLA1553 in Adult Participants with Human Immunodeficiency Virus (HIV)WithdrawnNCT06028841Phase 3
- Phase 2 Open-label Study of Alum-adjuvanted Chikungunya Virus-like Particle Vaccine (PXVX0317)CompletedNCT03992872Phase 21 country
- A Phase 3 Trial of the VLP-Based Chikungunya Vaccine PXVX0317 (CHIKV VLP Vaccine)CompletedNCT05072080Phase 31 country
- Population Immunity AgaiNst mosquitO-borne Diseases in VanuatuCompletedNCT05153018Not applicable1 country
- Sustainable Reduction of Dengue in Colombia: Vector Breeding Site Intervention With an Insecticidal CoatingCompletedNCT06268691Not applicable2 countries
- Sylvatic Transmission of Zika, Dengue, and Chikungunya Viruses in Thailand and CambodiaCompletedNCT044348461 country
- Consequences of a Maternal-fetal Chikungunya Virus InfectionCompletedNCT04909411Not applicable1 country
- Study to Demonstrate Consistency of Three Lots of a Live-attenuated Chikungunya Virus Vaccine Candidate in Healthy AdultsCompletedNCT04786444Phase 31 country