Carcinoma, Squamous Cell: all 1,779 studies

Page 2 of 18. Open to participants first (409), then studies with results posted, then the rest; newest registration first within each.

• Tumor Regression Grade As Predictor of Adjuvant TherapyRecruitingNCT06710665
• A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)RecruitingNCT06709417Phase 2
• Neoadjuvant Therapy of Targeted Immunotherapy Combined With Chemotherapy for Locally Advanced HNSCCNot yet recruitingNCT06699498Phase 2
• Trilaciclib for the Prevention of Chemoradiotherapy-Induced Myelosuppression in Esophageal Squamous Cell CarcinomaRecruitingNCT06698692
• Pembrolizumab in Combination with Flutamide Treatment for Recurrence / Metastasis HNSCCNot yet recruitingNCT06694350Phase 2
• Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCCRecruitingNCT06693323Phase 2
• Tislelizumab as Single-Agent Neoadjuvant Immunotherapy in Resectable Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06692270Phase 2
• Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of IPM514 in Patients with Esophageal Squamous Cell CarcinomaRecruitingNCT06690476Early Phase 1
• Evaluation of [18F]AlF-NOTA-PCP2 PET/CT for PD-L1 Detection in Malignant TumorsEnrolling by invitationNCT06690216Phase 1/2
• Study of Dalpiciclib Isethionate Plus Pyrotinib Maleate in the Treatment of Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT06684600Phase 2
• Cadonilimab Combined With Anlotinib Followed by Radiotherapy in Recurrent or Metastatic Esophageal Squamous Cell Carcinoma (CAR-RMEC)Not yet recruitingNCT06681285Phase 2
• Neoantigen Vaccines in Esophageal Squamous Cell CarcinomaRecruitingNCT06675201Phase 2
• Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial TreatmentRecruitingNCT06669572Phase 2
• A Study of Simmitinib Versus Chemotherapy for Participants With Advanced Oesophageal Squamous Cell CarcinomaNot yet recruitingNCT06656091Phase 3
• The Therapeutic Effect of Immunotherapy in Patients With Advanced Lung Squamous CarcinomaEnrolling by invitationNCT06647836
• Neoadjuvant Toripalimab + Chemotherapy ± Cetuximab in Locally Advanced Head and Neck Squamous Cell Carcinoma (Neo-ICT)Not yet recruitingNCT06647563Phase 3
• Fruquintinib in Combination With Tislelizumab Followed by Radiotherapy in Esophageal Squamous Cell CarcinomaRecruitingNCT06646588Phase 2
• Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell CarcinomasRecruitingNCT06642324
• Study of TPEx Followed by a Maintenance With Avelumab and Cetuximab in First Line Recurrent or Metastatic Squamous Cell Carcinoma of the H&NRecruitingNCT06640725Phase 2
• Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCCRecruitingNCT06637163Phase 2
• Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous SCC for Immunocompromised PatientsRecruitingNCT06615635Not applicable
• SBRT Followed by Chemoimmunotherapy of Toripalimab Plus Docetaxel and Cisplatin for Larynx Preservation in Patients with Locally Regionally Advanced Squamous Cell Carcinoma of the Larynx and HypopharynxRecruitingNCT06611137Phase 2
• NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG TechniqueNot yet recruitingNCT06610071Phase 1
• CHG0521 Oral Coating in Patients with Solid Tissue Tumor/Recurrent/Metastatic TSCCNot yet recruitingNCT06609070Not applicable
• Low-Dose Involved-Field Radiotherapy Plus Immunochemotherapy for ESCCRecruitingNCT06603402Phase 2
• Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative RadioimmunotherapyRecruitingNCT06602843Not applicable
• A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)RecruitingNCT06601335Phase 3
• Clinical Outcomes of Thoracodorsal Artery Flap in Oral and Maxillofacial ReconstructionNot yet recruitingNCT06599801
• Study of Adebrelimab With Chemotherapy, Endoscopy and Sequential Chemoradiotherapy In Inoperable Esophageal CancerNot yet recruitingNCT06599775Phase 2
• Phase 1 Clinical Trial of FluBHPVE6E7 Immunotherapy for HPV16-Associated Oropharyngeal CancerRecruitingNCT06589609Phase 1
• BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06588335Phase 2
• Surgery and Reducing Ionizing Radiation of the Unknown PrimaryNot yet recruitingNCT06578871Phase 2
• Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)RecruitingNCT06577311Phase 2
• Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell CarcinomaRecruitingNCT06576180
• Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell CarcinomaRecruitingNCT06575322
• Prediction of Local Recurrence and Its Impact on Long-term Outcomes After Low-risk Glans-sparing Surgery for Penile Squamous Cell CarcinomaEnrolling by invitationNCT06565585
• Sintilimab With Chemotherapy Plus PEG-rhG-GSF for Neoadjuvant Treatment of Esophageal Squamous Cell CarcinomaRecruitingNCT06563869Phase 3
• A Study of LY4050784 in Participants With Advanced or Metastatic Solid TumorsRecruitingNCT06561685Phase 1
• Individualized Tumor-Informed CtDNA Analysis for Monitoring Postoperative Recurrence in ESCC (NEOCRTEC2401)RecruitingNCT06561178
• Pilot Study of MPB-2043 Enhanced MRI for Nodal Staging in Head and Neck Squamous Cell CarcinomasRecruitingNCT06540443Phase 1
• AK112 Plus AP Regimen for Operable Locally Advanced Head and Neck Squamous Cell CarcinomaNot yet recruitingNCT06537011Phase 2
• B-catenin in Cutaneous Squamous Cell Carcinoma and Its MimickersRecruitingNCT06536946
• A Phase II Study of MRG003 Injection Combined With Pucotenlimab Injection ± Cisplatin Injection in the Neoadjuvant Treatment Locally Advanced EGFR-positive Head and Neck Squamous Cell CarcinomaNot yet recruitingNCT06530914Phase 2
• A Study of Simmitinib Plus Irinotecan in Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT06512428Phase 2
• Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCCRecruitingNCT06510660Phase 2
• A Phase II Study of Anti-EGFR Antibody-drug Conjugate (ADC) Combine With CDK4/6 Inhibitors Posterior Line in the Treatment of Recurrent/Metastatic CDKN2A Gene Variant Head and Neck Squamous Cell CarcinomaNot yet recruitingNCT06509997Phase 2
• Adebrelimab Combined With Albumin Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable ESCCNot yet recruitingNCT06508229Phase 2
• Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive CarcinomaNot yet recruitingNCT06505551Phase 1/2
• AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic TherapyRecruitingNCT06494995Phase 2
• Induction IBI110 and Sintilimab with Chemotherapy in LA HNSCCRecruitingNCT06494943Phase 1/2
• Liposomal Irinotecan With Cisplatin and Concurrent Radiotherapy in Locally Advanced Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06491134Phase 1
• AK112 Combined With Chemotherapy as the First-line Treatment in Advanced Esophageal Squamous Cell Carcinoma PatientsRecruitingNCT06489197Phase 2
• A Phase lb/lI Clinical Study in Advanced or Metastatic Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06487702Phase 2
• Prognostic Value of Measuring CtDNA in a Cohort of Patients With Stage III and IV Upper Aero-digestive Tract (UADT) Cancer , Treated With Curative RADiOtherapy With or Without Concomitant Treatment.RecruitingNCT06479070Not applicable
• Stratification of Cutaneous Squamous Cell Carcinomas According to Its Transcriptomic, Metabolic and Inflammatory CharacteristicsRecruitingNCT06476964Not applicable
• Prospective Cohort Study of Neoadjuvant Therapy With Sintilimab (PD-1 Inhibitor) Combined With Chemotherapy in Resectable ESCCEnrolling by invitationNCT06475196
• Tirilizumab with Albumin-bound Paclitaxel and Cisplatin for Locally Advanced Resectable Oral Squamous Cell CarcinomaRecruitingNCT06470217Phase 2
• Short-course Radiotherapy Combined With Sintilimab for Neoadjuvant Treatment of Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06468670Phase 2
• Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06468644Phase 2
• A Study of Sintilimab Combined With Chemotherapy for Neoadjuvant Treatment of Esophageal Squamous Cell CarcinomaRecruitingNCT06463834Phase 2
• Study of the Relationship Between Clinical, Imaging and Biological Data in Patients With Squamous Cell Carcinoma of the TongueRecruitingNCT06450080Not applicable
• Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell CarcinomaRecruitingNCT06446726Phase 2
• A Study of VET3-TGI in Patients With Solid TumorsRecruitingNCT06444815Phase 1
• A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell CarcinomaRecruitingNCT06444009Phase 2
• Mechanism Study to Investigate Difference in Efficacy of Neoadjuvant Chemoimmunotherapy in Lung Squamous Cell CarcinomaRecruitingNCT06436040
• Cytosponge in Surveillance After Endoscopic Submucosal Dissection for Esophageal Squamous Cell CarcinomaEnrolling by invitationNCT06429865Not applicable
• Neoadjuvant Cadonilimab Combined With Anlotinib in Locally Advanced Resectable Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06426797Phase 2
• Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)RecruitingNCT06425146Not applicable
• Sequential Tegafur-gimeracil-oteracil Potassium Capsule (s-1) and Serplulimab Following Concurrent Chemoradiotherapy for Esophageal Squamous Cell CarcinomaRecruitingNCT06422858Phase 2
• Early Detection of Esophageal Squamous Cancer With the Capsule Sponge DeviceNot yet recruitingNCT06418516Not applicable
• Sintilimab After Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell CarcinomaRecruitingNCT06413342Phase 2
• Multimodal Endoscopic Image Fusion for Assessing Infiltration in Superficial Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06412419
• Short-course Hypofractionated Radiotherapy in Combination With Raltitrexed and TislelizumabRecruitingNCT06408584
• Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After TreatmentNot yet recruitingNCT06407570
• Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06388135Phase 4
• Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS)RecruitingNCT06385730Phase 2
• Raman Spectroscopy and Skin CancerRecruitingNCT06384924
• Neoadjuvant Targeted Therapy in Patients With Resectable EGFR-mutated Lung Squamous Cell CarcinomaRecruitingNCT06383728Phase 2
• Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and OutcomeRecruitingNCT06380686
• BAI-BACE for Advanced Lung Squamous Cell CarcinomaRecruitingNCT06377735Not applicable
• Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCCNot yet recruitingNCT06366945Phase 2
• Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated with ImiquimodRecruitingNCT06356012Phase 4
• A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT06354530Phase 2/3
• PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDYRecruitingNCT06354140Phase 2
• Dermatoscopy Guided Resection for Skin CancerRecruitingNCT06342297Not applicable
• Laser Ablation in the Treatment of High-grade Cervical LesionsNot yet recruitingNCT06333743Not applicable
• Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Clinically Node-negative Head and Neck Squamous Cell CarcinomaRecruitingNCT06323369Phase 2
• Neoadjuvant SBRT in Localized Advanced HNSCCRecruitingNCT06306846Phase 2
• Pembrolizumab Combined With Preoperative Chemotherapy (Albumin Paclitaxel+Carboplatin) Neoadjuvant Therapy for Resectable Locally Advanced (Stage II/III) Esophageal Squamous Cell CarcinomaRecruitingNCT06304350Phase 2
• Neoadjuvant Chemoradiotherapy Followed by Sequential Immunotherapy for Thoracic Esophageal Squamous Cell CarcinomaEnrolling by invitationNCT06303583Phase 1/2
• The Combination of Adebrelimab and TP Regimen for Neoadjuvant Therapy in Patients With Stage IVB Oral Squamous Cell CarcinomaRecruitingNCT06277791Phase 2
• Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma in the Era of ImmunotherapyRecruitingNCT06272214Phase 2
• Outcomes of Smoker and Drinker With Esophageal Squamous Cell Carcinoma After EsophagectomyRecruitingNCT06269341
• Accurate Diagnosis of the Invasion Depth in ESCC by a Deep Neural Network Analysis of NBI Endoscopy DataNot yet recruitingNCT06252974
• a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer PatientsRecruitingNCT06248996Phase 3
• Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell CarcinomaRecruitingNCT06235918Phase 2
• Neoadjuvant Adebrelimab With Dalpiciclib for Resectable Esophageal Squamous Cell CarcinomasRecruitingNCT06225921Phase 1
• SBRT Followed by Neoadjuvant Chemoimmunotherapy of Sindilizumab Plus Docetaxel and Cisplatin for Locoregionally Advanced Squamous Carcinoma of Oral Cavity and OropharynxRecruitingNCT06219980Phase 2
• Envafolimab Combined With Chemotherapy in Neoadjuvant and Conversion Therapy for Head and Neck Squamous Cell CarcinomaNot yet recruitingNCT06218004Phase 2
• ctDNA and MRI Parameters in Head and Neck CancerNot yet recruitingNCT06215612Not applicable

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