CClinicalTrials.gg
Not yet recruitingNCT06252974Updated Apr 29, 2024

Accurate Diagnosis of the Invasion Depth in ESCC by a Deep Neural Network Analysis of NBI Endoscopy Data

An observational study in Esophageal Squamous Cell Carcinoma, sponsored by RenJi Hospital. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-04-29.

Sponsored by RenJi Hospital · Observational

From the registry’s dates

  • Primary completion was expected by May 2024, 2 years 4 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
500
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this observational study is to accurate diagnose the stage of esophageal squamous cell carcinoma in order to help physicians to decide the appropriate clinical treatment. The main question it aims to answer is:

  • To get early accurate diagnosis of the invasion depth of esophageal squamous cell carcinoma by narrow-band imaging endoscopy data.

Participants' clinical informations from routine examinations and treatments will be collected, there will be no harm to participants.

02

Conditions studied

03

In context

Carcinoma

6,741 studies on the registry are indexed under Carcinoma; 1,161 are open to participants now.

This study's planned enrollment of 500 is above the median of 149 across 1,175 observational studies indexed under Carcinoma.

Browse Carcinoma studies →

Lead sponsor

RenJi Hospital is the lead sponsor of 535 studies on the registry; 244 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Around 500 cases.

Inclusion criteria

  1. Age ≥ 18 years old, regardless of gender;
  2. Performing esophageal ESD surgery due to esophageal mucosal lesions;
  3. Pathological evaluation of ESD specimens.

Exclusion criteria

Exclusion Criteria:

Pathological examination after ESD surgery ruled out esophageal squamous cell carcinoma.

05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
500 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Accurate diagnose the invasion depth of early esophageal squamous cell carcinoma by endoscopy NBI images through deep neural network analysis

    We will compare the predictive performance of InvaDepNet before and after incorporating data generated using GAN and demonstrated that including the generated data in the training dataset effectively improves the accuracy of the predictive model. Additionally, we will train six commonly used CNN models on two datasets with different shooting angles (including NBI without magnifying and NBI with magnifying), and we will propose a ResNet model to analysis the clinical informations combine with NBI images.

    Time frame: 2024/12/31

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 29, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06252974
Lead sponsor
RenJi Hospital
Responsible party
Sponsor
First posted
Feb 12, 2024
Start date
Apr 25, 2024 (estimated)
Primary completion
May 31, 2024 (estimated)
Completion
Dec 31, 2024 (estimated)
Last update
Apr 29, 2024

Study contacts

Hui Ding, Doctor
Contact
dr_daisy@163.com
+8613585966417

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion