Brugada Syndrome clinical trials
The registry lists 53 studies for Brugada Syndrome across more than 10 countries. 19 are recruiting or about to start. 41 of them are mainly about Brugada Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Universitair Ziekenhuis Brussel (7) · IRCCS Policlinico S. Donato (5) · Pacific Rim Electrophysiology Research Institute (3) · University of Sao Paulo General Hospital (2) · Nantes University Hospital (2) · Imperial College London (2) · University Hospital, Montpellier (2) · University of British Columbia (2)
What is being tested here
Drugs under test in Brugada Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Nov 2026Unmasking Concealed Arrhythmia Syndromes · Imperial College London
- Aug 2027Empagliflozin as a Potential Therapeutic Solution for Patients With Brugada Syndrome · National Taiwan University Hospital
Who these studies take
Of the 15 Brugada Syndrome studies recruiting now, 10 (67%) set no upper age limit and 0 (0%) stop at 75 or younger. 6 (40%) take children under 18. 1 (7%) are for women only and 0 (0%) for men only; 5 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (33%) | 5 (33%) |
| 18 | 15 (100%) | 14 (93%) |
| 30 | 15 (100%) | 14 (93%) |
| 40 | 15 (100%) | 14 (93%) |
| 50 | 15 (100%) | 14 (93%) |
| 65 | 15 (100%) | 14 (93%) |
| 75 | 15 (100%) | 14 (93%) |
| 85 | 14 (93%) | 13 (87%) |
Across all 53 studies, recruiting or not: 15% stop at 75 or younger and 8% at 65; 38% take children; 2% are for women only and 0% for men only; 28% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- Southeast Asian Brugada Syndrome CohortOct 30, 2026NCT04232787
Studies
Recruiting first, then most recently updated. Showing 50 of 53. Browse all 53 → or search them.
- Southeast Asian Brugada Syndrome CohortRecruitingNCT042327871 country
- Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada SyndromeRecruitingNCT076551021 country
- Sudden Unexplained Death in Childhood (SUDC) RegistryRecruitingNCT031091971 country
- Distribution of Cell-cell Junction Proteins in Arrhythmic DisordersRecruitingNCT042579941 country
- National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter RegistryRecruitingNCT065461371 country
- Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal DemiseRecruitingNCT037759541 country
- Analysis of the Presence and Cardiac Functional Effects of Anti-NaV1.5 Autoantibodies in Patients With Metastatic TumorsNot yet recruitingNCT07364656Not applicable1 country
- Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac ArrhythmiasEnrolling by invitationNCT024134501 country
- Empagliflozin as a Potential Therapeutic Solution for Patients With Brugada SyndromeNot yet recruitingNCT07146880Phase 21 country
- Brugada Syndrome Substrate Characterization and AblationRecruitingNCT05643209Not applicable1 country
- Unmasking Concealed Arrhythmia SyndromesRecruitingNCT069881891 country
- GenLab: Unveiling the Genetic Landscape of Brugada Syndrome: Novel Biomarker Discovery for Precise DiagnosisRecruitingNCT066479271 country
- Clinical Cohort Study - TRUSTRecruitingNCT055214511 country
- DNA Methylation in Brugada Syndrome and Risk of Sudden Cardiac DeathNot yet recruitingNCT06888271
- Epicardial Ablation in Brugada Syndrome. An Extension Study of 500 BrS.PatientsRecruitingNCT03106701Not applicable1 country
- UZ Brussel HRMC Registry of Brugada SyndromeRecruitingNCT052837591 country
- Drug-induced Brugada Syndrome Research DatabaseRecruitingNCT050486021 country
- China Inherited Ventricular Arrhythmias RegistryRecruitingNCT038807081 country
- Worm Study: Modifier Genes in Sudden Cardiac DeathRecruitingNCT02014961Not applicable1 country
- Healthy-related Quality of Life and Physical Activity of Children With Cardiac MalformationsCompletedNCT04712136Not applicable1 country
- Epicardial Radiofrequency Catheter Ablation in Patients With Brugada SyndromeCompletedNCT05685134Not applicable1 country
- Impact on Risk Stratification of Overlap Syndrome Phenotype in Patients With E1784K Mutation in SCN5ACompletedNCT052746461 country
- VF Mapping in Brugada and Early Repolarization SyndromesCompletedNCT037645921 country
- Brugada Ablation of VF Substrate Ongoing MultiCenter RegistryCompletedNCT044200781 country
- Ablation in Brugada Syndrome for the Prevention of VFCompletedNCT02704416Not applicable2 countries
- The Conus Brugada Syndrome StudyCompletedNCT066535041 country
- High Density Mapping in Brugada SyndromeCompletedNCT065676391 country
- Artificial Intelligence for the Prioritization of Genetic Background in Brugada SyndromeCompletedNCT063765521 country
- Safety of Local Dental Anesthesia in Patients With Cardiac ChannelopathiesCompletedNCT03182777Not applicable1 country
- Feasibility of Improving Risk Stratification in Brugada SyndromeCompletedNCT039926771 country
- Physical Activity in Children With Inherited Cardiac DiseasesCompletedNCT046500091 country
- Effects of Propofol-Induced Anaesthesia on the ST-segment of the ECGStatus unknownNCT051854011 country
- Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective TrialStatus unknownNCT045809921 country
- European Perioperative Brugada SurveyStatus unknownNCT04808193Not applicable1 country
- Right Ventricle Morphology and Hemodynamics in BrSCompletedNCT035240791 country
- DAPERB 3,4-DiAminoPyridine and Electrophysiological Response in Brugada SyndromeTerminatedNCT00701077Phase 31 country
- Brugada Syndrome and Artificial Intelligence Applications to DiagnosisStatus unknownNCT04641585Not applicable1 country
- Registry of Unexplained Cardiac ArrestCompletedNCT002920321 country
- Long Term Monitoring for Risk of Sudden DeathCompletedNCT041242371 country
- Validation Of A New S-ICD Algorithm To Reduce Oversensing Of Dynamic T-Waves In Patients With Brugada SyndromeTerminatedNCT045045913 countries
- Empiric Quinidine for Asymptomatic Brugada SyndromeWithdrawnNCT00789165Phase 2/36 countries
- The Response To Ajmaline Provocation in Healthy SubjectsStatus unknownNCT02933437Phase 21 country
- Evaluation of Subcutaneous Implantable Cardiac Defibrillator in Brugada PatientsCompletedNCT023442775 countries
- Diagnostic Value and Safety of Flecainide Infusion Test in Brugada SyndromeCompletedNCT023022741 country
- AnalyST & Brugada Syndrome - Feasibility StudyCompletedNCT02052765Not applicable1 country
- Rhythmic Risk of Type 1 Brugada Syndrome and Pulmonary Infundibulum MappingStatus unknownNCT03572881Not applicable1 country
- Echocardiography During Ajmaline TestStatus unknownNCT034914751 country
- The Brugada Syndrome: a Follow-up StudyStatus unknownNCT034855081 country
- Ripple Mapping for Epicardial Mapping of Brugada SyndromeStatus unknownNCT034353933 countries
- Epicardial Ablation in Brugada SyndromeCompletedNCT02641431Not applicable1 country