Bronchitis, Chronic clinical trials
The registry lists 209 studies for Bronchitis, Chronic across more than 10 countries. 14 are recruiting or about to start. 119 of them are mainly about Bronchitis, Chronic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
AstraZeneca (12) · GlaxoSmithKline (12) · Sumitomo Pharma America, Inc. (7) · Bayer (6) · University of Alberta (5) · Imperial College London (5) · Royal Brompton & Harefield NHS Foundation Trust (5) · Gala Therapeutics, Inc. (5)
What is being tested here
Drugs under test in Bronchitis, Chronic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| GSK573719 | 1 | 0 | 3 |
| Fluticasone | 1 | 0 | 3 |
| Guaifenesin | 1 | 0 | 2 |
| Vilanterol | 1 | 0 | 2 |
| Galvokimig | 1 | 0 | 1 |
| Brenipatide | 1 | 0 | 1 |
| Fluticasone furoate | 1 | 0 | 1 |
| Azithromycin | 0 | 6 | 9 |
| Aclidinium | 0 | 7 | 8 |
| Aclidinium bromide | 0 | 7 | 7 |
Drug classes tested here Antimuscarinics 1 open · Corticosteroids 1 open · Bronchodilators 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Apr 2027Repeat Treatment With Metered Cryospray in Patients With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis · CSA Medical, Inc.
- Oct 2027A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD · Upstream Bio Inc.
Who these studies take
Of the 10 Bronchitis, Chronic studies recruiting now, 5 (50%) set no upper age limit and 2 (20%) stop at 75 or younger. 1 (10%) take children under 18. 1 (10%) are for women only and 0 (0%) for men only; 3 (30%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (10%) | 1 (10%) |
| 18 | 2 (20%) | 2 (20%) |
| 30 | 3 (30%) | 3 (30%) |
| 40 | 9 (90%) | 8 (80%) |
| 50 | 10 (100%) | 9 (90%) |
| 65 | 10 (100%) | 9 (90%) |
| 75 | 9 (90%) | 8 (80%) |
| 85 | 6 (60%) | 5 (50%) |
Across all 209 studies, recruiting or not: 20% stop at 75 or younger and 4% at 65; 7% take children; <1% are for women only and 2% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Bronchitis, Chronic studies take
Of 14 phase 2 interventional studies under Bronchitis, Chronic, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 18 mo11–20 · 14 studies | — | — |
| Interventional, no phase | 35 mo28–47 · 24 studies | — | — |
| Observational | 50 mo36–114 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 209. Browse all 209 → or search them.
- A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic BronchitisRecruitingNCT07725939Phase 22 countries
- A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)RecruitingNCT07759245Phase 218 countries
- Study to Evaluate the Effects of Oral Glyceryl Guiacolate (Guaifenesin, GGE) on Sputum Rheology in Subjects With Mucus HypersecretionNot yet recruitingNCT07873632Phase 41 country
- COPD Resources, Education, and Activity Designed for You StudyRecruitingNCT07125053Not applicable1 country
- Emphysema Research Registry and Biosample RepositoryRecruitingNCT003072811 country
- Repeat Treatment With Metered Cryospray in Patients With Chronic Obstructive Pulmonary Disease With Chronic BronchitisNot yet recruitingNCT07468617Not applicable
- The Italian Registry of Patients With Chronic Obstructive Pulmonary DiseaseEnrolling by invitationNCT066527761 country
- Clinical Study of the Pulsed Electric Field Ablation System in Chronic Obstructive Pulmonary DiseaseRecruitingNCT07068438Not applicable1 country
- Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer ScreeningRecruitingNCT061220771 country
- Pulmonary Deposition of Ultrasound Rock Salt Aerosol Inhalation TherapyNot yet recruitingNCT06891274Not applicable1 country
- Effect of the Inhaled Triple Therapies Over the Small Airway in Biomass ExposureRecruitingNCT06571942Phase 41 country
- EFFECT OF PRANAYAMA YOGA ON COPDRecruitingNCT06022627Not applicable1 country
- RheOx Registry Study in EuropeRecruitingNCT04182841Not applicable2 countries
- COPD Patient-Powered Research NetworkRecruitingNCT028032421 country
- Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD)Active, not recruitingNCT006087641 country
- Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) StudyCompletedNCT011776181 country
- Metered Cryospray for the Treatment of Patients With Chronic Obstructive Pulmonary Disease With Chronic BronchitisCompletedNCT03892694Not applicable2 countries
- A Clinical Evaluation of the RheOx Bronchial Rheoplasty SystemCompletedNCT05641207Not applicable1 country
- Roflumilast or Azithromycin to Prevent COPD Exacerbations TrialCompletedNCT04069312Phase 31 country
- Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole CathetersCompletedNCT01828788Phase 21 country
- The Effects of Oscillatory Positive Expiratory Pressure (OPEP) Therapy in Patients With COPDCompletedNCT06614959Not applicable1 country
- A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPDActive, not recruitingNCT06981078Phase 223 countries
- A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis.CompletedNCT05843669Phase 41 country
- PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT00683722Phase 21 country
- A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)TerminatedNCT04636814Phase 328 countries
- A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER)TerminatedNCT04636801Phase 330 countries
- A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic CoughCompletedNCT05660850Phase 24 countries
- Study of COPD Subgroups and BiomarkersActive, not recruitingNCT019693441 country
- Evaluation of Effectiveness of the Treatment After Repeated Administration of Klacid®SRCompletedNCT011308831 country
- Investigation of Chronic Obstructive Pulmonary Disease (COPD) Phenotypes and Endotypes in ChinaCompletedNCT048532251 country
- Efficacy and Safety of Broncho Muco Cleaner Balloon Dilation TherapyCompletedNCT05868941Not applicable1 country
- BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioImage StudyActive, not recruitingNCT030492021 country
- Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary DiseaseActive, not recruitingNCT026278721 country
- A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in ChinaCompletedNCT053371631 country
- A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic BronchitisCompletedNCT04631016Phase 215 countries
- Evaluation of Immunological, Microbiological and Metabolomic Profiles in COPDCompletedNCT068265601 country
- The Topic Trial - Study to Determine the Safety and Efficacy of IvacaftorCompletedNCT03085485Phase 21 country
- RejuvenAir® System Trial for COPD With Chronic BronchitisActive, not recruitingNCT03893370Not applicable2 countries
- Effects of Pursed Lip Breathing Technique Versus Stacked Breathing Technique Among Chronic Bronchitis PatientsCompletedNCT06242210Not applicable1 country
- Dose of Corticosteroids in COPDTerminatedNCT01742338Phase 41 country
- Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILEActive, not recruitingNCT05649046Not applicable1 country
- Etiology of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in JapanCompletedNCT039575771 country
- Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke CigarettesCompletedNCT05610514Phase 21 country
- Comparison Of Blow Bottle Positive Expiratory Pressure (BBPEP) Versus Acapella Among Patient With Chronic BronchitisCompletedNCT06086730Not applicable1 country
- Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow ObstructionCompletedNCT008716371 country
- Efficacy and Safety of Levalbuterol in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT00665600Phase 32 countries
- Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic BronchitisActive, not recruitingNCT04677465Not applicable5 countries
- Study of Humidified Air to Improve Mucociliary Clearance (MCC) in COPDCompletedNCT03935932Not applicable1 country
- Patient-Centred Innovations for Persons With Multimorbidity - OntarioCompletedNCT02742597Not applicable1 country
- Feasibility Study of the Pulsed Electric Field Ablation System in Treating Chronic BronchitisStatus unknownNCT05771129Not applicable1 country