Anal Canal Carcinoma clinical trials

The registry lists 33 studies for Anal Canal Carcinoma across more than 10 countries. 8 are recruiting or about to start. 17 of them are mainly about Anal Canal Carcinoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.

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Status

Completed: 14
Recruiting: 6
Active, not recruiting: 6
Status unknown: 2
Not yet recruiting: 2
Terminated: 2

Phase

Phase 2: 18
Phase 3: 6

Where

United States: 13
France: 7
Canada: 5
Brazil: 3
China: 2
United Kingdom: 1

Who runs them

Centre Hospitalier Universitaire de Besancon (4) · National Cancer Institute (NCI) (3) · ECOG-ACRIN Cancer Research Group (3) · Sixth Affiliated Hospital, Sun Yat-sen University (2) · Instituto do Cancer do Estado de São Paulo (2) · Radiation Therapy Oncology Group (2) · AHS Cancer Control Alberta (2) · AIDS Malignancy Consortium (2)

What is being tested here

Drugs under test in Anal Canal Carcinoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Pembrolizumab	1	0	1
Fluorouracil	0	2	7
Mitomycin	0	1	4
Cisplatin	0	1	4
Nivolumab	0	2	3
Capecitabine	0	0	3
Cetuximab	0	0	2
Ipilimumab	0	0	1
Carboplatin	0	0	1
Paclitaxel	0	0	1

Drug classes tested here Immune checkpoint inhibitors 2 open · Antimetabolites 9

Coming up

3phase 3 studies under way

6studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6, phase 3 first

Mar 2027EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients · Phase 3 · National Cancer Institute (NCI)
Dec 2026Dynamic ctDNA Assessment in Cervical and Anal Canal Tumors: Optimizing Follow-up and Clinical Outcomes · Instituto do Cancer do Estado de São Paulo
Dec 2026Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases · University of Sao Paulo
Apr 2027Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers · University of California, San Francisco
Oct 2027Assessment of Sexual Quality of Life Following Local Treatment (Radiotherapy With or Without Surgery) in Patients With HPV-positive Pelvic Cancer: a Descriptive Longitudinal Study · Institut du Cancer de Montpellier - Val d'Aurelle
Nov 2027IMRT Versus IMPT With Concurrent Chemotherapy for Locally Advanced Anal Canal Cancer · Tata Memorial Centre

Who these studies take

Of the 6 Anal Canal Carcinoma studies recruiting now, 4 (67%) set no upper age limit and 1 (17%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 6
Age	Women	Men
10	0 (0%)	0 (0%)
18	6 (100%)	6 (100%)
30	6 (100%)	6 (100%)
40	6 (100%)	6 (100%)
50	6 (100%)	6 (100%)
65	6 (100%)	6 (100%)
75	6 (100%)	6 (100%)
85	4 (67%)	4 (67%)

Across all 33 studies, recruiting or not: 12% stop at 75 or younger and 0% at 65; 6% take children; 6% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 33 of 33. search them.