An interventional study of protein supplement and protein supplement in Hydration, sponsored by Loughborough University. Not yet recruiting at 1 site in United Kingdom. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-06.
Sponsored by Loughborough University · Not applicable, Interventional, and Treatment
This study will examine the effects of protein drinks on markers of hydration in healthy young males and females.
Loughborough University is the lead sponsor of 76 studies on the registry; 13 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Are not between the ages of 18-40. If you are not considered at least recreationally physically active (at least meeting the WHO criteria) - Tier 1 or Tier 2 on the Participant Classification Framework (https://pubmed.ncbi.nlm.nih.gov/34965513/).
Have metabolic, inflammatory, vascular, renal disease or any other complication that would contradict the study procedures or risk your health.
Currently taking medication or supplements that may interfere with the study outcomes.
Protein (10 g of protein powder and 500 ml of water)
Dietary Supplement: protein supplement
Protein (10 g of protein powder, 500 ml of water, sodium chloride, 20 mmol/L)
Dietary Supplement: protein supplement
Water (500 ml)
Other: Placebo control
10 g of protein powder in 500 ml water
10 g of protein powder, plus sodium chloride (20 mmol/L) in 500 ml of water
Water (500 ml)
Urine output (mass in grams over 180 min collection period)
Time frame: 180 minutes
Subjective measures of thirst (Likert scale, 0-10; 0 = low, 10 = high)
Time frame: Pre - then 30, 60, 120, 180 mins post
Urine specific gravity (AU)
Time frame: Pre - then 60, 120, 180 mins post
Blood sodium concentrations (mmol)
Time frame: Pre - then 30, 60, 120, 180 mins post
Blood chloride concentrations (mmol)
Time frame: Pre - then 30, 60, 120, 180 mins post
Blood potassium (mmol)
Time frame: Pre - then 30, 60, 120, 180 mins post
Urine sodium (mmol)
Time frame: Pre - then 30, 60, 120, 180 mins post
Urine chloride (mmol)
Time frame: Pre - then 30, 60, 120, 180 mins post
Urine potassium (mmol)
Time frame: Pre - then 30, 60, 120, 180 mins post
Plasma volume change (% change)
Time frame: Pre - then 60, 180 minutes
Plasma albumin concentrations
ELISA measurement
Time frame: Pre - then 60, 180 minutes
Plasma aldosterone concentrations
ELISA measurement
Time frame: Pre - then 60, 180 minutes
Subjective measure of hunger (Likert scale, 0-10; 0 = low, 10 = high)
Time frame: Pre - then 30, 60, 120, 180 mins post
Subjective measure of gastrointestinal stress (Likert scale, 0-10; 0 = low, 10 = high)
Time frame: Pre - then 30, 60, 120, 180 mins post
Plasma insulin concentrations
ELISA measurement
Time frame: Pre - then 60, 180 minutes
Subjective measures of hunger (Likert scale, 0-10; 0 = low, 10 = high)
Time frame: Pre - then 30, 60, 120, 180 mins post
Subjective measures of stomach fullness (Likert scale, 0-10; 0 = low, 10 = high)
Time frame: Pre - then 30, 60, 120, 180 mins post
Subjective measures of nausea (Likert scale, 0-10; 0 = low, 10 = high)
Time frame: Pre - then 30, 60, 120, 180 mins post
Beverage hydration index (AU)
Calculated as the ratio of cumulative urine mass for water/cumulative urine mass of the test beverages
Time frame: Pre - then 30, 60, 120, 180 mins post
Plasma osmolality (mOsm/L)
Time frame: Pre - 60, 180 mins post
Blood glucose (mmol/L)
Time frame: Pre - then 30, 60, 120, 180 mins post
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Protein Supplement
Loughborough University