An observational study in Cerebral Palsy, Early Assessment and Early Rehabilitation Intervention, sponsored by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico. Enrolling by invitation at 1 site in Italy. Open to participants aged 3 Months to 18 Months, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-04.
Sponsored by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Observational
Early identification of cerebral palsy (CP) has improved with the combined use of the General Movements Assessment (GMA), the Hammersmith Infant Neurological Examination (HINE) and magnetic resonance imaging (MRI). Emerging evidence indicates that the incorporation of additional instruments, may further enhance specificity and facilitate comorbidity identification. However, predicting motor subtype and functional prognosis in infancy remains difficult. The Neurofunctional Assessment (NFA) is a global tool, originally developed for preterm infants, that focuses on the development of normal functions and is based on the International Classification of Functioning, Disability and Health (ICF) approach. This study focuses on seven postural-motor manoeuvres drawn from the full NFA (squatting, balancing, supine-to-sit righting, ventral suspension, axillary suspension, lateral suspension and guided rolling), which assess three domains: axial control, distal selective motor control and lateral asymmetries.
1,898 studies on the registry are indexed under Cerebral Palsy; 439 are open to participants now.
This study's planned enrollment of 30 is below the median of 63 across 469 observational studies indexed under Cerebral Palsy.
Browse Cerebral Palsy studies →Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico is the lead sponsor of 233 studies on the registry; 81 are open to participants now.
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cerebral palsy or infants at neurological risk
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Exclusion Criteria:
To determine whether domain-specific findings from the seven-manoeuvre NFA battery support earlier and more precise characterisation of CP motor subtype and functional prognosis.
gmfm
The Gross Motor Function Measure (GMFM-88) is a standardized observational instrument designed and validated to measure changes in gross motor function over time in children with cerebral palsy (CP)
Time frame: every 6 months up to 2 years
GMDS
Griffiths Scales of Child Development (Third Edition, or Griffiths III) is a standardized, play-based assessment tool used to measure a child's overall development and create a detailed profile of strengths and needs from birth to 5 years and 11 months of age.
Time frame: 2 years
gmds
The GMDS (Griffiths Mental Development Scales) is one of the most widely used and internationally recognized standardized instruments for assessing global development in infants, toddlers, and young children. Originally designed by psychologist Ruth Griffiths, the scales are used to detect developmental delays, track clinical progress, and construct a comprehensive profile of a child's developmental strengths and difficulties.
Time frame: at the end of the study
Ran from Mar 2026 to primary completion in Sep 2026, 6 months.
Of 210 non-industry observational studies under Cerebral Palsy, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 59. This study's 6 months is below that.
Counting every sponsor, half of 214 studies reached it within 20 months; a quarter within 8 and three quarters within 59.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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