An interventional study of resin guide group and metal guide group in Atrophic Maxilla, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 21 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-03.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Oral rehabilitation with dental implants in patients with severely atrophic maxillae often presents significant surgical challenges. Guided implant placement has been introduced to improve the accuracy of three-dimensional implant positioning and reduce the risk of complications associated with complex anatomical structures.
This prospective split-mouth clinical study aimed to compare the accuracy of zygomatic implant placement using two different materials for patient-specific stackable surgical guides: resin and metal.
Fifteen patients requiring bilateral zygomatic implant placement were included in the study. Each patient received a metallic surgical guide on one side and a resin surgical guide on the contralateral side.
Patient-specific surgical guides were designed using preoperative computed tomography (CT) data and three-dimensional virtual implant planning. Postoperative CT images were registered with the preoperative plans to evaluate deviations between the planned and actual implant positions.
Implant placement accuracy was assessed by measuring coronal, apical, and angular deviations. The study aimed to evaluate the influence of surgical guide material on the accuracy of guided zygomatic implant placement.
Preoperative Preparation
All patients underwent implant placement surgery under general anesthesia following appropriate preoperative preparation and investigations.
Preoperative investigations included:
Flap Design and Reflection
A paracrestal palatal incision extending bilaterally from the maxillary tuberosities was performed.
The mucoperiosteal flap was reflected to expose the lateral wall of the maxillary sinus and the zygomatic process, extending superiorly toward the infraorbital foramen and posteriorly to expose the zygomatic bone.
Surgical Guide Stabilization
The patient-specific surgical guides were stabilized using miniscrews fixed to the exposed maxillary buttress to guide implant positioning, angulation, and drilling depth.
Zygomatic Implant Placement
Implant osteotomies were performed using two sequential zygomatic drills through the prefabricated surgical drilling guides.
The implants were transferred to the prepared osteotomy sites using their fixture mounts and manually inserted until their apical ends reached the planned positions within the zygomatic bone.
The fixture mounts were then removed. After confirming implant stability, cover screws were placed and secured.
Postoperative Instructions
All patients received written postoperative instructions and prescriptions for their postoperative medications.
30 studies on the registry are indexed under Atrophic Maxilla; 11 are open to participants now.
This study's enrollment of 15 is close to the median of 16 across 27 interventional studies indexed under Atrophic Maxilla.
Browse Atrophic Maxilla studies →Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Paracrestal palatal incision extend bilaterally from tuberosities will be performed. The flap will be reflected to expose the lateral wall of the maxillary sinus as well as the zygomatic process anteriorly inferiorly and superiorly up to infraorbital foramen and its posterior border the flap will be retracted from the superior border of zygoma. resin Guides with be stabilized using mini screws on the exposed maxillary buttress to guide the implant direction and depth to ensure that the zygomatic implant is placed in the best location.
Device: resin guide group
Paracrestal palatal incision extend bilaterally from tuberosities will be performed. The flap will be reflected to expose the lateral wall of the maxillary sinus as well as the zygomatic process anteriorly inferiorly and superiorly up to infraorbital foramen and its posterior border the flap will be retracted from the superior border of zygoma. metal Guides with be stabilized using mini screws on the exposed maxillary buttress to guide the implant direction and depth to ensure that the zygomatic implant is placed in the best location.
Device: metal guide group
Paracrestal palatal incision extend bilaterally from tuberosities will be performed. The flap will be reflected to expose the lateral wall of the maxillary sinus as well as the zygomatic process anteriorly inferiorly and superiorly up to infraorbital foramen and its posterior border the flap will be retracted from the superior border of zygoma. resin Guides with be stabilized using mini screws on the exposed maxillary buttress to guide the implant direction and depth to ensure that the implant is placed in the best location. Zygomatic implants
Paracrestal palatal incision extend bilaterally from tuberosities will be performed. The flap will be reflected to expose the lateral wall of the maxillary sinus as well as the zygomatic process anteriorly inferiorly and superiorly up to infraorbital foramen and its posterior border the flap will be retracted from the superior border of zygoma. Metal Guides with be stabilized using mini screws on the exposed maxillary buttress to guide the implant direction and depth to ensure that the implant is placed in the best location. Zygomatic implants
coronal deviation of zygomatic implant placement measured using CT ( mm)
coronal deviation was measured in millimeter as linear distance between planned and actual coronal positions of zygomatic implant. measurements were obtained by comparing the preoperative virtual plan with the postoperative CT scan using image registration. Lower deviation value indicate greater implant placement accuracy
Time frame: two weeks
apical deviation of zygomatic implant placement measured using CT ( mm)
apical deviation was measured in millimeter as linear distance between planned and actual apical positions of zygomatic implant. measurements were obtained by comparing the preoperative virtual plan with the postoperative CT scan using image registration. Lower deviation value indicate greater implant placement accuracy
Time frame: two weeks
angular deviation of zygomatic implant placement measured using CT ( degrees)
angular deviation was measured in degrees as the angle between the planned and actual long axis of the zygomatic implant. measurements were obtained by comparing the preoperative virtual implant plan with the postoperative CT scan using the image registration , lower angular deviation value indicate greater implant placement accuracy
Time frame: two weeks
Rate of postoperative biological complications
Postoperative complications were assessed through clinical examination and postoperative computed tomography (CT) imaging, as appropriate to each complication, during the first four months following zygomatic implant placement. Clinical and radiographic findings were recorded to identify postoperative complications, including sinusitis, sensory disturbances, and implant-related complications. Patients who developed complications received additional follow-up until clinical resolution.
Time frame: up to four months after implant placement
Ran from Sep 2024 to primary completion in Jan 2026, 16 months.
Of 20 interventional studies with no phase under Atrophic Maxilla, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 32. This study's 16 months is below that.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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