An interventional study of Complex dermal layer repair and surgical closure materials in Wounds and Scar Revision, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 16 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-03.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
This study evaluates a complex dermal layer repair technique for the treatment of facial wounds, with the objective of preventing scar widening and reducing scar visibility. The technique is used in patients with acute facial cut wounds and in patients undergoing facial scar revision. Scar outcomes are assessed using the Patient and Observer Scar Assessment Scale (POSAS) at six months.
The surgical technique involves wound cleansing, local anaesthesia, de-epithelialization of one wound edge over an approximately 2 mm width, preparation of the opposing deep dermal edge, and approximation of the wound's deep layers with absorbable sutures. The de-epithelialized edge is anchored beneath the dermis of the opposing edge using 6-0 PDS sutures. The superficial skin layer is closed with 6-0 polypropylene sutures, with Steri-Strips applied as supplementary support. Skin sutures are removed within five to seven days.
2,217 studies on the registry are indexed under Wounds and Injuries; 441 are open to participants now.
This study's enrollment of 40 is below the median of 70 across 1,424 interventional studies indexed under Wounds and Injuries.
Browse Wounds and Injuries studies →Cairo University is the lead sponsor of 4,941 studies on the registry; 1,457 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Exclusion criteria
intervention
Procedure: Complex dermal layer repair · Device: surgical closure materials · Drug: local anaesthetic and adrenaline infiltration
Complex dermal layer repair
Absorbable sutures for deep-layer approximation; 6-0 PDS sutures for dermal anchoring; 6-0 polypropylene sutures for superficial skin closure; and Steri-Strips for supplementary wound support.
Also known as: Skin closure
Injection of adrenaline 1:150000 solution + Lidocaine 2% by a dose suitable to the wound length (1 cc for each 1 cm)
Scar quality assessed using the Patient and Observer Scar Assessment Scale (POSAS)
The Patient and Observer Scar Assessment Scale (POSAS) is a validated clinical and research tool used to evaluate scar quality from two independent perspectives: the clinician (Observer Scale) and the patient (Patient Scale). Structure and Scoring: * Scoring Range: Each item is scored on a numeric scale from 1 (like normal skin) to 10 (worst scar imaginable). * Overall Opinion: Both the observer and the patient provide a separate overall opinion score from 1 to 10. * Total Score: Calculated by summing the individual item scores (ranging from 6 to 60 for each scale).
Time frame: Six months after the procedure
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No — There is no plan to share individual participant data (IPD) collected in this study with other researchers.
Ran from Dec 2021 to primary completion in Dec 2024, 36 months.
Of 547 non-industry interventional studies with no phase under Wounds and Injuries, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 49. This study's 36 months is above that.
Counting every sponsor, half of 600 studies reached it within 24 months; a quarter within 9 and three quarters within 48.
Wounds and Injuries covers many different conditions, not one, so the studies compared here vary widely. Read these figures as a rough guide.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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