An interventional study of Adaptive Gamified Sensory Training and Conventional Physical Therapy Group in Diabetic Peripheral Neuropathy, sponsored by Al-Zaytoonah University of Jordan. Not yet recruiting. Open to participants aged 45 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-11-04.
Sponsored by Al-Zaytoonah University of Jordan · Not applicable, Interventional, and Treatment
Diabetic peripheral neuropathy (DPN) will be considered a clinically important complication of diabetes mellitus that may impair sensory function and interfere with the performance of daily activities involving the hands and feet. Sensory deficits may affect tactile perception, object manipulation, foot-related functional tasks, and the ability to interact safely with the surrounding environment.
The purpose of this study will be to investigate the effects of adaptive gamified sensory training combined with conventional physical therapy on sensory function, sensory integration during balance, and hand functional performance in patients with diabetic peripheral neuropathy.
Al-Zaytoonah University of Jordan is the lead sponsor of 31 studies on the registry; 6 are open to participants now.
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Exclusion Criteria
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The therapist will additionally record tactile discrimination accuracy, selected games, application settings, and progression between task levels.
Other: Adaptive Gamified Sensory Training
upper-limb conventional exercises Lower-limb strengthening: Conventional balance exercises: Gait and functional mobility training:
Other: Conventional Physical Therapy Group
Participants will receive a 6-week intervention consisting of three sessions per week (18 sessions total), with each session lasting 90 minutes. The intervention will include 30 minutes of conventional physical therapy, 30 minutes of upper-limb sensory training involving tactile sensory discrimination and interactive gamified hand exercises using a Bluetooth-connected ball, and 30 minutes of lower-limb sensory training involving progressive, task-oriented activities using visual targets, safe textured surfaces, texture matching, and controlled foot placement and weight shifting. Task difficulty will be progressively adjusted according to participants' performance and tolerance. Device and tools: Bluetooth-connected interactive squeeze ball Foam balance pad Textured sensory stimulation materials Visual floor targets
Participants will receive a 6-week conventional rehabilitation program consisting of three sessions per week (18 sessions total), with each session lasting 90 minutes. The program will include 30 minutes of shared conventional physical therapy, 15 minutes of upper-limb range-of-motion and functional exercises, 15 minutes of lower-limb strengthening exercises, 15 minutes of balance training, and 15 minutes of gait and functional mobility training. Exercises will be adapted to participants' functional abilities and safety requirements. devices and tools: Foam balance pad Textured sensory stimulation materials Visual floor targets
Neuropathy Impairment Scale (NIS) - Sensory Subset
Change in sensory function from baseline to 6 weeks, assessed using the sensory subset of the Neuropathy Impairment Scale (NIS). Assessment includes touch pressure, pinprick, vibration, and joint position at the right and left index fingers and great toes. Higher scores indicate greater sensory impairment. Grading: NIS Sensory Subset * 0 = Normal sensation * 1 = Decreased sensation * 2 = Absent sensation Scale title: Neuropathy Impairment Scale - Sensory Subset (NIS Sensory Subset). Minimum value: 0 Maximum value: 32\* Interpretation: Higher scores indicate worse sensory impairment; lower scores indicate better sensory function.
Time frame: 6 weeks
Jebsen-Taylor Hand Function Test (JTHFT)
Change in hand functional performance from baseline to post-intervention at 6 weeks, assessed using the Jebsen-Taylor Hand Function Test. Grading: Performance time in seconds for each subtest. Shorter completion times indicate better hand function. * Unabbreviated scale title: Jebsen-Taylor Hand Function Test. * Minimum value: 0 seconds (theoretical minimum). * Maximum value: No fixed maximum; the score is recorded as the time required to complete each task. * Interpretation: Higher scores (longer completion times) indicate worse hand function, whereas lower scores (shorter completion times) indicate better hand function. Important: The JTHFT consists of seven timed subtests. Report the completion time in seconds for each subtest rather than treating it as a conventional 0-100 scale.
Time frame: 6 weeks
Biodex Balance System-Modified Clinical Test of Sensory Interaction on Balance (mCTSIB), if this is the specific test selected for your protocol. Device Biodex Balance System
Condition 1: Eyes Open on a Firm Surface The participant stands on a firm, stable surface with eyes open. Visual, somatosensory, and vestibular information are available. Condition 2: Eyes Closed on a Firm Surface The participant stands on a firm, stable surface with eyes closed. Visual input is removed, increasing reliance on somatosensory and vestibular information. Condition 3: Eyes Open on a Foam Surface The participant stands on a foam surface with eyes open. The foam reduces the reliability of somatosensory information from the feet and ankles. Condition 4: Eyes Closed on a Foam Surface The participant stands on a foam surface with eyes closed. Both visual input and reliable somatosensory information are reduced, increasing reliance on vestibular information. Lower sway values generally indicate less postural sway and better postural stability. Higher sway values: generally indicate greater postural sway and poorer postural stability.
Time frame: 6 weeks
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Nov 2026; primary completion for Dec 2026, 1 month later.
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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Al-Zaytoonah University of Jordan