ClinicalTrials.gg
Not yet recruitingNCT07899203Updated Oct 27, 2026

Effect of Progressive Gamified Motor Rehabilitation After Carpal Tunnel Release

An interventional study of gamified motor rehabilitation and conventional physical therapy treatment for patient with carpal tunnel syndrome in Carpal Tunnel Surgery, sponsored by Al-Zaytoonah University of Jordan. Not yet recruiting. Open to participants aged 40 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-10-27.

Sponsored by Al-Zaytoonah University of Jordan · Not applicable, Interventional, and Treatment

Updated Oct 27, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
40 Years to 65 Years
Sex
All
01

Study summary

Carpal tunnel syndrome is the most common peripheral entrapment neuropathy and may result in sensory and motor impairment, particularly in patients with severe disease and thenar muscle atrophy. Progressive gamified motor rehabilitation using sensor-based interactive technology may provide an engaging approach to facilitate repetitive, task-oriented hand and thumb movements while allowing progression according to the individual's performance and tolerance. However, the effectiveness of incorporating such an approach into conventional postoperative rehabilitation in patients with severe carpal tunnel syndrome and thenar atrophy remains unclear.

02

Conditions studied

  • Carpal Tunnel Surgery

Keywords

  • carpal tunnel release
  • game therapy
  • electrophysiological study
03

In context

Lead sponsor

Al-Zaytoonah University of Jordan is the lead sponsor of 31 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with unilateral severe carpal tunnel syndrome confirmed by clinical and electrophysiological assessment.
  • Presence of thenar muscle atrophy on clinical examination.
  • Patients who have undergone carpal tunnel release surgery for the affected hand.
  • Medically cleared by the treating surgeon to participate in postoperative hand rehabilitation.
  • Adequate wound healing allowing initiation of the prescribed rehabilitation program.
  • Ability to understand and follow verbal and written instructions.
  • Ability to perform the required hand and thumb movements safely.
  • Willingness to participate in the complete rehabilitation program and outcome assessments.
  • Provision of written .

Exclusion criteria

Exclusion Criteria:

  • Previous surgery or major trauma involving the affected wrist or hand.
  • Other peripheral neuropathies affecting the upper limb or hand.
  • Cervical radiculopathy, cervical myelopathy, or other neurological disorders that may affect hand function.
  • Coexisting neurological disorders affecting upper-limb motor function.
  • Musculoskeletal conditions of the shoulder, elbow, wrist, or hand that significantly limit hand function or interfere with the intervention.
  • Bilateral carpal tunnel syndrome requiring simultaneous rehabilitation of both hands.
  • Previous carpal tunnel release surgery on the same hand.
  • Postoperative complications that prevent or substantially limit participation in rehabilitation.
  • Severe cognitive, visual, or communication impairment that prevents understanding or performing the intervention.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

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You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    Gamified motor group

    received gamified motor rehabilitation and conventional treatment

    Other: gamified motor rehabilitation

  • Active comparator
    Standard therapy group

    received conventional treatment (hand grip strengthening exercise functional care training)

    Other: conventional physical therapy treatment for patient with carpal tunnel syndrome

Interventions

  • Othergamified motor rehabilitation

    uses interactive smartphone apps connected with small ball via Bluetooth to turn standard hand and thumb exercises into engaging, game-like tasks.

  • Otherconventional physical therapy treatment for patient with carpal tunnel syndrome

    * Nerve Gliding (Neurodynamic) Exercises: Gentle movements of the wrist, fingers, and head help the median nerve slide smoothly through the carpal tunnel and prevent it from sticking to surrounding tissues. * Tendon Gliding Exercises: Specific finger and hand sequences (such as moving from a straight hand to a hook, full fist, and tabletop position) encourage smooth tendon movement and decrease swelling. * Stretching \& Strengthening: Gentle flexor and extensor stretches improve flexibility, while progressive strengthening exercises for the hand, wrist, and forearm are introduced once acute symptoms subside.

06

What researchers measure

Primary outcomes

  1. Median Nerve Motor Distal Latency and Motor Conduction Velocity

    Median nerve motor distal latency (DL), measured in milliseconds (ms), and motor conduction velocity (MCV), measured in meters per second (m/s), will be assessed using a nerve conduction study before and after the intervention to evaluate motor nerve conduction following carpal tunnel release.

    Time frame: 6 weeks

Secondary outcomes

  1. Arabic Version of the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) Questionnaire

    Upper-limb disability and symptoms will be assessed using the Arabic version of the QuickDASH questionnaire, an 11-item patient-reported outcome measure. The total score ranges from 0 to 100, with higher scores indicating greater disability. The questionnaire will be administered at baseline and immediately after the intervention to assess changes in upper-limb functional status.

    Time frame: 6 weeks

  2. Arabic Version of the Boston Carpal Tunnel Questionnaire (BCTQ) Score

    Carpal tunnel syndrome symptoms and functional limitations will be assessed using the Arabic version of the Boston Carpal Tunnel Questionnaire (BCTQ), a patient-reported outcome measure consisting of two subscales: the Symptom Severity Scale (SSS; 11 items) and the Functional Status Scale (FSS; 8 items). Each item is scored on a 1-5 scale, with higher scores indicating greater symptom severity and functional limitation. The questionnaire will be administered at baseline and immediately after the intervention.

    Time frame: 6 weeks

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Oct 2026; primary completion for Dec 2026, 2 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 18, 2026
First posted
Oct 27, 2026
StartEst.
Oct 25, 2026
Primary completionEst.
Dec 31, 2026
CompletionEst.
Jan 10, 2027
Last update
Oct 27, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 27, 2026
Show all 1 update
  1. Oct 27, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07899203
Lead sponsor
Al-Zaytoonah University of Jordan
Responsible party
Hanan Hosny M Battesha (Associate professor, Al-Zaytoonah University of Jordan) — Principal investigator
First posted
Oct 27, 2026
Start date
Oct 25, 2026 (estimated)
Primary completion
Dec 31, 2026 (estimated)
Completion
Jan 10, 2027 (estimated)
Last update
Oct 27, 2026

Study contacts

hanan mohamed, associate professor
Contact
h.hosny@zuj.edu.jo
+962775661825

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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