An observational study in Ischemic Stroke and Stroke Rehabilitaion, sponsored by Medical University of Lodz. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-27.
Sponsored by Medical University of Lodz · Observational
This observational study evaluates the effects of neurological rehabilitation on biological markers associated with neuroplasticity and neurotransmitter profiles in patients after ischemic stroke. The study will include patients at different stages after stroke who undergo neurological rehabilitation as part of their standard care. The aim of the study is to assess whether rehabilitation is associated with changes in neuroplasticity-related markers and neurotransmitter levels, which may contribute to a better understanding of recovery processes after ischemic stroke.
Stroke is one of the leading causes of long-term disability worldwide. Neurological rehabilitation plays a key role in promoting functional recovery after ischemic stroke, but the biological mechanisms underlying rehabilitation-induced neuroplasticity are not fully understood.
This prospective observational study aims to investigate the association between neurological rehabilitation and changes in the expression of neuroplasticity-related biomarkers and neurotransmitter profiles in patients at different stages following ischemic stroke. Participants will receive standard neurological rehabilitation according to routine clinical practice. Biological samples and clinical assessments will be collected at predefined time points to evaluate changes associated with the rehabilitation process.
The findings of this study may improve the understanding of the molecular mechanisms involved in post-stroke recovery and contribute to the identification of biomarkers associated with rehabilitation outcomes. This knowledge may support the development of more personalized rehabilitation strategies for patients after ischemic stroke.
2,612 studies on the registry are indexed under Ischemic Stroke; 971 are open to participants now.
This study's planned enrollment of 60 is below the median of 300 across 771 observational studies indexed under Ischemic Stroke.
Browse Ischemic Stroke studies →Medical University of Lodz is the lead sponsor of 107 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult patients with ischemic stroke (ICD-10: I63) hospitalized in the Neurological Rehabilitation Department. The study population will include patients in different phases after stroke, including the early subacute phase and the late subacute phase (approximately 3-6 months after stroke). Participants will undergo a standard neurological rehabilitation program and will be assessed for changes in neuroplasticity-related markers and neurotransmitter profiles.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients with ischemic stroke in the early subacute phase undergoing standard neurological rehabilitation.
Patients with ischemic stroke in the late subacute phase (approximately 3-6 months after stroke) undergoing neurological rehabilitation.
Expression of Neuroplasticity Markers and Neurotransmitter Profiles
Assessment of changes in the expression of neuroplasticity-related markers and neurotransmitter profiles in blood samples collected from patients with ischemic stroke undergoing neurological rehabilitation. The analysis will compare biomarker levels between patients in different stages after stroke and evaluate changes associated with the rehabilitation process.
Time frame: At baseline and after 4 weeks of neurological rehabilitation
No study locations are listed for this record.
Plan to share: No — Individual participant data will not be shared with other researchers.
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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