An interventional study of Transobturator Autologous Vaginal Wall Sling and Autologous Rectus Sheath Pubovaginal Slinge in Stress Urinary Incontinence (SUI), sponsored by Mohamed Ehab Saad Fadl. Completed at 1 site in Egypt. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-27.
Sponsored by Mohamed Ehab Saad Fadl · Not applicable, Interventional, and Treatment
Among 39 studies in Urinary Incontinence, Stress with a site in Egypt — 15 open to participants now, 19 under way, none of them phase 3. Urinary Incontinence, Stress · Egypt.
Among the 39 studies in Urinary Incontinence, Stress with a site in Egypt, this one is the 24th largest by enrollment of the 31 interventional ones that give a count, is one of 5 that started in 2025, is one of 23 with no phase, and was the 39th registered.
653 studies on the registry are indexed under Urinary Incontinence, Stress; 121 are open to participants now.
Browse Urinary Incontinence, Stress studies →15 of the 39 studies in Urinary Incontinence, Stress with a site in Egypt are open now. Recruiting first, the newest first:
Benha University · Sites in Egypt
Ages 18+ · Women only
Benha University · Sites in Egypt
Ages 50–65 · Women only · Healthy volunteers
Al-Azhar University · Sites in Egypt
Ages 20–45 · Women only
Cairo University · Sites in Egypt
Ages 40–60 · Women only
Cairo University · Sites in Egypt
Ages 18–65 · Women only
A study can be open while its sites in Egypt have not opened yet or have stopped. Only those recruiting at a site in Egypt →
Of the 74 Urinary Incontinence, Stress studies recruiting now, 42 (57%) set no upper age limit and 18 (24%) stop at 75 or younger; 2 take children under 18; 16 take healthy volunteers.
This study: 18 Years and older · female · no healthy volunteers.
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39 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 2 5 · Phase 3 6
First in 2014; this study’s year is marked. 5 started in 2025.
This study's enrollment of 40 is below the median of 68 across 508 interventional studies indexed under Urinary Incontinence, Stress.
Median enrollment 60 across the 31 interventional studies, 122 across the 8 observational. Of the 14 that completed or were terminated, 0 (0%) have results posted.
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1 of 39 have an industry lead sponsor. The 10 most frequent:
This is the only study on the registry with Mohamed Ehab Saad Fadl as lead sponsor.
Mohamed Ehab Saad Fadl has 1 study filed under Urinary Incontinence, Stress — fewer than ten, so there is no comparison to draw.
4 of the studies in Urinary Incontinence, Stress with a site in Egypt that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07661264Cairo UniversityEffect of Different Pelvic Floor Loading Techniques on Women With Stress Urinary Incontinence | 2026-12-15 |
| NCT07762300Benha UniversityHybrid Transobturator Tape Versus Conventional Synthetic Tape for Stress Urinary Incontinence | 2027-03-01 |
| NCT07807982Benha UniversityPeri-Urethral Platelet-Rich Plasma Injections for Postmenopausal Female Stress Urinary Incontinence | 2027-03-15 |
| NCT07550426Ain Shams UniversityThe Effect of Periurethral Injection of Platelet Rich Plasma Versus Mid-urethral Sling in Treatment of Stress Urinary Incontinence | 2027-04-15 |
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Among the 39 studies in Urinary Incontinence, Stress with a site in Egypt, from their registry updates:
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This study compares two operations for stress urinary incontinence in adult women. Stress urinary incontinence means leaking urine during activities such as coughing, sneezing, laughing, or exercising. Women with both stress-related leakage and a sudden urgent need to urinate were also eligible if stress-related leakage was their main problem.
Both operations use the woman's own tissue to create a sling that supports the urethra, the tube that carries urine out of the bladder. One operation uses tissue from the vaginal wall, placed through openings in the pelvic bones near the groin (a transobturator vaginal wall sling). The other uses tissue from the strong layer covering the abdominal muscles (a rectus sheath pubovaginal sling). Neither operation uses synthetic mesh, although permanent supporting stitches are used.
Forty women at Kafrelsheikh University Hospitals, Egypt, were randomly assigned to one of the two operations, with 20 women in each group. Follow-up continued for six months after surgery.
The main question is whether the operations differ in preventing urine leakage during a cough test six months after surgery. The study also compares urinary symptoms, operation duration, urine flow, bladder emptying, and complications.
This single-center, prospective, exploratory randomized comparative study enrolled 40 adult women undergoing surgical treatment for stress urinary incontinence at Kafrelsheikh University Hospitals, Egypt. Participants were allocated equally to transobturator autologous vaginal wall sling surgery or autologous rectus sheath pubovaginal sling surgery. The sample size was based on feasibility and the limited preliminary evidence available for the vaginal wall technique.
Eligible participants had stress urinary incontinence with a positive cough stress test or mixed urinary incontinence with a predominant stress component. Exclusion criteria included urgency-predominant mixed urinary incontinence, bleeding disorders, active urinary tract infection, underactive bladder with a large post-void residual urine volume, and previous pelvic irradiation.
Preoperative assessment included medical, urinary, obstetric, and surgical histories; a voiding diary; the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF); pelvic examination; and cough stress testing. Investigations included laboratory testing, urine culture, pelvic ultrasonography, measurement of post-void residual urine volume, and uroflowmetry. Urodynamic testing was performed selectively when clinically indicated.
Allocation was concealed using sequentially numbered, sealed, opaque envelopes. Group assignment was disclosed to the operating surgeon immediately before surgery. Postoperative assessments were performed by clinicians who were not involved in the surgical procedures.
The transobturator vaginal wall sling procedure used an approximately 6 × 2 cm autologous anterior vaginal wall graft, supported by permanent polypropylene suspension sutures passed through the obturator route. The rectus sheath pubovaginal sling procedure used an autologous rectus fascial strip harvested through a lower abdominal incision and positioned at the bladder neck or proximal urethra through a retropubic approach. Intraoperative cystoscopy was performed in both groups to check for bladder or urethral injury.
Postoperative follow-up visits were scheduled at 1, 2, 4, and 12 weeks and at six months. Assessments included urinary symptoms, cough stress testing, bladder emptying, wound healing, pain, urgency, and voiding dysfunction. The six-month assessment also included the ICIQ-UI SF and uroflowmetry. Postoperative complications were classified using the Clavien-Dindo system.
The primary outcome was objective continence at six months, defined as the absence of visible urine leakage during a standardized cough stress test. Secondary assessments included urinary symptom scores, operative time, postoperative complications, and urinary functional outcomes.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Participants underwent transobturator autologous vaginal wall sling surgery
Procedure: Transobturator Autologous Vaginal Wall Sling
Participants underwent autologous rectus sheath pubovaginal sling surgery.
Procedure: Autologous Rectus Sheath Pubovaginal Slinge
An approximately 6 × 2 cm graft harvested from the participant's anterior vaginal wall is positioned beneath the midurethra. Permanent polypropylene suspension sutures are passed bilaterally through the obturator foramina using an outside-in approach. The sling is positioned without tension and secured to the periurethral tissues. Intraoperative cystoscopy is performed to exclude bladder or urethral injury.
An autologous rectus sheath graft measuring approximately 6-8 cm in length and 1.5-2 cm in width is harvested through a lower abdominal Pfannenstiel incision. The graft is positioned at the bladder neck or proximal urethra, with permanent polypropylene suspension sutures passed through the retropubic space to the suprapubic region. Intraoperative cystoscopy is performed to exclude bladder or urethral injury.
Percentage of Participants With Objective Cure on Cough Stress Testing
Objective cure is defined as the absence of visible urine leakage during a standardized cough stress test at the six-month postoperative assessment. Participants with visible urine leakage during the test are classified as treatment failures.
Time frame: 6 months after surgery
Change in ICIQ-UI Short Form Score
Change from baseline in the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) total score. Scores range from 0 to 21, with higher scores indicating greater urinary incontinence severity and impact. A decrease indicates improvement.
Time frame: Baseline and 6 months after surgery
Operative Time
Duration of the surgical procedure, measured in minutes.
Time frame: During surgery
Percentage of Participants With Postoperative Complications
Percentage of participants experiencing postoperative complications, with complications classified according to the Clavien-Dindo classification.
Time frame: From surgery through 6 months after surgery
Plan to share: Yes — De-identified individual participant data underlying the reported study results will be shared, including baseline demographic and clinical characteristics, assigned surgical intervention, cough stress test outcomes, ICIQ-UI Short Form scores, operative time, uroflowmetry measurements, post-void residual urine volume, and postoperative complications. Names, contact details, medical record numbers, and other identifying information will not be shared.
Supporting information: Study protocol
Time frame: Beginning 6 months after publication of the study results and continuing for 3 years thereafter.
Access criteria: Qualified researchers may request access to de-identified individual participant data underlying the published results, the study protocol, and a data dictionary by contacting the principal investigator using the email listed in the study record. Requests must include a scientifically sound research proposal and analysis plan. Access will be granted following review by the study team, subject to applicable institutional and ethics requirements and a signed data use agreement. Approved files will be provided through a secure electronic transfer.
Ran from Feb 2025 to primary completion in Feb 2026, 12 months.
Of 226 non-industry interventional studies with no phase under Urinary Incontinence, Stress, half reached primary completion within 19 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 43. This study's 12 months is below that.
Counting every sponsor, half of 267 studies reached it within 19 months; a quarter within 9 and three quarters within 43.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Urinary Incontinence, Stress →